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Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation
Tetracycline repressor (TetR) family regulators (TFRs) are the largest group of DNA-binding transcription factors and are widely distributed in...
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Highly active repeat-mediated recombination in the mitogenome of the aquatic grass Hygroryza aristata
BackgroundFloating bamboo ( Hygroryza aristata ) is an endangered species with a narrow native distribution and is renowned for its unique aesthetic...
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De novo assembly of the complete mitochondrial genome of sweet potato (Ipomoea batatas [L.] Lam) revealed the existence of homologous conformations generated by the repeat-mediated recombination
Sweet potato ( Ipomoea batatas [L.] Lam) is an important food crop, an excellent fodder crop, and a new type of industrial raw material crop. The lack...
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MicrosatNavigator: exploring nonrandom distribution and lineage-specificity of microsatellite repeat motifs on vertebrate sex chromosomes across 186 whole genomes
Microsatellites are short tandem DNA repeats, ubiquitous in genomes. They are believed to be under selection pressure, considering their high...
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Complete mitochondrial genome of Melia azedarach L., reveals two conformations generated by the repeat sequence mediated recombination
Melia azedarach is a species of enormous value of pharmaceutical industries. Although the chloroplast genome of M. azedarach has been explored, the...
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Characterisation of the complete mitochondrial genome of Taraxacum mongolicum revealed five repeat-mediated recombinations
Key messageWe reported the mitochondrial genome of Taraxacum mongolicum for the first time. Five pairs of repeats that can mediate recombination...
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Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG
The clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 system is a research hotspot in gene therapy. However, the widely used Streptococ...
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Comparative analysis of the chloroplast and mitochondrial genomes of Saposhnikovia divaricata revealed the possible transfer of plastome repeat regions into the mitogenome
BackgroundSaposhnikovia divaricata (Turcz.) Schischk. is a perennial herb whose dried roots are commonly used as a source of traditional medicines....
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Characterization and mitigation of artifacts derived from NGS library preparation due to structure-specific sequences in the human genome
BackgroundHybridization capture-based targeted next generation sequencing (NGS) is gaining importance in routine cancer clinical practice. DNA...
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Subty** Salmonella isolated from pet dogs with multilocus sequence ty** (MLST) and clustered regularly interspaced short palindromic repeats (CRISPRs)
Salmonella , as a zoonotic pathogen, has attracted widespread attention worldwide, especially in the transmission between household pets and humans....
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The complete plastomes of red fleshed pitaya (Selenicereus monacanthus) and three related Selenicereus species: insights into gene losses, inverted repeat expansions and phylogenomic implications
Selenicereus is a genus of perennial shrub from the family Cactaceae, and some of them play an important role in the food industry, pharmaceuticals,...
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A willow sex chromosome reveals convergent evolution of complex palindromic repeats
BackgroundSex chromosomes have arisen independently in a wide variety of species, yet they share common characteristics, including the presence of...
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Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Associated Proteins (Cas) [CRISPR–Cas]: An Emerging Technique in Plant Disease Detection and Management
A great challenge has come to scientists to provide food to every person of the growing population that will reach nearly ten billion globally within... -
Characterization and diversity of CRISPR/Cas systems in Klebsiella oxytoca
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated protein) system is a crucial adaptive immune system for...
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The chloroplast genome of Camellia sinensis var. assamica cv. Duntsa (Theaceae) and comparative genome analysis: mutational hotspots and phylogenetic relationships
Camellia sinensis (L.) O. Kuntze var. assamica cv. Duntsa (herein C. duntsa ) has been used since ancient times in Hunan, China. To understand the...
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Analysis of chloroplast genome characteristics and codon usage bias in 14 species of Annonaceae
For the study of species evolution, chloroplast gene expression, and transformation, the chloroplast genome is an invaluable resource. Codon usage...
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Transgenic Strategies and Genome Editing for Nutritional Enrichment
The agriculture sector is facing severe challenges in producing high-quality food materials in significant quantities because of climate change and... -
Analysis of the chloroplast genome and phylogenetic evolution of Bidens pilosa
Chloroplast genomes for 3 Bidens plants endemic to China ( Bidens bipinnata Linn., Bidens pilosa Linn., and Bidens alba var. radiata ) have been...
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The complete plastid genome and characteristics analysis of Achillea millefolium
Achillea is a crop with Chinese herbal characteristics and horticultural values. Its leaves and flowers contain aromatic oil, and the ripe herb can...
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Assembly of the complete mitochondrial genome of an endemic plant, Scutellaria tsinyunensis, revealed the existence of two conformations generated by a repeat-mediated recombination
Main conclusionWe assembled the complete mitochondrial genome of Scutellaria tsinyunensis in this study. Repeat-mediated recombination resulted in...