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Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS
BackgroundAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the...
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Insecticidal effect of green walnut husks and its active basis digesting targeting to insect phenoloxidase using UPLC-Q-TOF-MS coupled with PLS analysis
The immature fruit exocarp of Juglans mandshurica Maxim., also called “green walnut husks” (GWH), are usually discarded as food waste. Although GWH...
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Growth, physiological, and temperature characteristics in chinese cabbage pakchoi as affected by Cd- stressed conditions and identifying its main controlling factors using PLS model
BackgroundAlthough hormesis induced by heavy metals is a well-known phenomenon, the involved biological mechanisms are not fully understood. Cadmium...
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So you think you can PLS-DA?
BackgroundPartial Least-Squares Discriminant Analysis (PLS-DA) is a popular machine learning tool that is gaining increasing attention as a useful...
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Feature selection using distributions of orthogonal PLS regression vectors in spectral data
Feature selection, which is important for successful analysis of chemometric data, aims to produce parsimonious and predictive models. Partial least...
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A novel NIRS modelling method with OPLS-SPA and MIX-PLS for timber evaluation
The identification of timber properties is important for safe application. Near Infrared Spectroscopy (NIRS) technology is widely-used because of its...
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German farmers’ intention to use autonomous field robots: a PLS-analysis
Autonomous field robots are a promising technology for solving several problems in agriculture, as they are electrical driven, can control weeds...
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Effect of wood surface roughness on prediction of structural timber properties by infrared spectroscopy using ANFIS, ANN and PLS regression
Predicting the properties of structural timber using a rapid and reliable non-destructive method is a critical quality control task in production....
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Papillon–Lefèvre syndrome (PLS) with novel compound heterozygous mutation in the exclusion and Peptidase C1A domains of Cathepsin C gene
Papillon Lefevre syndrome (PLS) manifests with palmoplantar keratoderma, combined with a rapidly progressive periodontitis associated with mutations...
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On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations
Associations between datasets can be discovered through multivariate methods like Canonical Correlation Analysis (CCA) or Partial Least Squares...
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Chrysin-loaded PEGylated liposomes protect against alloxan-induced diabetic neuropathy in rats: the interplay between endoplasmic reticulum stress and autophagy
BackgroundDiabetic neuropathy (DN) is recognized as a significant complication arising from diabetes mellitus (DM). Pathogenesis of DN is accelerated...
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The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank
Large-scale genome-wide association studies (GWAS) strongly suggest that most traits and diseases have a polygenic component. This observation has...
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Polar lipids modify Alzheimer’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation
BackgroundPro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (Aβ) peptides are a well-described pathology in...
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Enteric and systemic postprandial lactate shuttle phases and dietary carbohydrate carbon flow in humans
Dietary glucose in excess is stored in the liver in the form of glycogen. As opposed to direct conversion of glucose into glycogen, the hypothesis of...
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Automatic tree detection and attribute characterization using portable terrestrial lidar
Key messageThis study details a methodology to automatically detect the positions of and dasometric information about individual Eucalyptus trees...
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A rapid and nondestructive method for the prediction of lignin content in tropical Amazon woods using FT-NIR spectroscopy
Nondestructive methods have been used to predict different technological characteristics of wood. The study evaluated multivariate PLS (partial least...
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Contribution of cryptochromes and photolyases for insect life under sunlight
The cryptochrome/photolyase (CRY/PL) family is essential for life under sunlight because photolyases repair UV-damaged DNA and cryptochromes are...
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Ability of near infrared spectroscopy to detect anthracnose disease early in mango after harvest
Determining anthracnose-infested mango can involve laborious and time-consuming assays, resulting in delayed postharvest management and decreased...
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The effect of ensiled paulownia leaves in a high-forage diet on ruminal fermentation, methane production, fatty acid composition, and milk production performance of dairy cows
BackgroundThe use of industrial by-products rich in bioactive compounds as animal feeds can reduce greenhouse gas production. Paulownia leaves silage...
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A novel approach using ATR-FTIR spectroscopy and chemometric analysis to distinguish male and female human hair samples
This article presents an attempt to discriminate between human male and female hair samples using a single strand of scalp hair. The methodology...
