Search
Search Results
-
Identification of phosphoenolpyruvate carboxykinase 1 as a potential therapeutic target for pancreatic cancer
Pancreatic cancer is the third leading cause of cancer-related mortalities and is characterized by rapid disease progression. Identification of novel...
-
Acetyl Phosphate Acetylates Proteins of Streptomyces coelicolor M-145
AbstractProtein Nε-lysine acetylation is a ubiquitous posttranslational modification. Acetylation in eukaryotes and prokaryotes can perform by...
-
Core Transcriptome of Hydrogen Producing Marine Vibrios Reveals Contribution of Glycolysis in Their Efficient Hydrogen Production
Pyruvate (Pyr) is the end product of the glycolysis pathway. Pyr is also renewable and is further metabolized to produce formate, which is the...
-
Role of C4 photosynthetic enzyme isoforms in C3 plants and their potential applications in improving agronomic traits in crops
As compared to C3, C4 plants have higher photosynthetic rates and better tolerance to high temperature and drought. These traits are highly...
-
A New Glance on the Mechanism of Autotrophic CO2 Assimilation in Green Sulfur Bacteria
Abstract —The autotrophic system of CO 2 fixation in Chlorobaculum limnaeum strain C consists of two topologically independent enzyme complexes: the...
-
Gluconeogenese, Glykogen, Disaccharide und Pentosephosphatweg
Woher kommt die Glucose, welche der Zelle über Glykolyse, Citratzyklus und oxidative Phosphorylierung die Synthese von ATP ermöglicht? Glucose wird... -
Decarboxylation mechanisms of the C4 cycle in foxtail millet observed under salt and selenium treatments
Foxtail millet ( Setaria italica L.), a millet with a smaller genome and shorter life cycle, growing in arid and semi-arid areas, is severely affected...
-
Increasing the pyruvate pool by overexpressing phosphoenolpyruvate carboxykinase or triosephosphate isomerase enhances phloroglucinol production in Escherichia coli
ObjectivesAcetyl-CoA is a precursor for phloroglucinol (PG), and pyruvate is one of the sources of intracellular acetyl-CoA. Therefore, enhancing...
-
Photosynthese ist mit Wasserverbrauch verbunden
Bei der Photosynthese wird sehr viel Wasser verbraucht. Häufig ist das der Pflanze zur Verfügung stehende Wasser begrenzt. Bestimmte Pflanzen können... -
[13C]bicarbonate labelled from hyperpolarized [1-13C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
Hyperpolarized [1- 13 C]pyruvate enables direct in vivo assessment of real-time liver enzymatic activities by 13 C magnetic resonance. However, the...
-
The phosphoenolpyruvate-pyruvate-oxaloacetate node genes and enzymes in Streptomyces coelicolor M-145
The phosphoenolpyruvate-pyruvate-oxaloacetate node is a major branch within the central carbon metabolism and acts as a connection point between...
-
C4 Equivalent Decarboxylation Competence in Tropical Orchids
Tropical xero-epiphytic orchids undergo a photosynthetic mechanism called ‘Crassulacean Acid Metabolism’, a modification of Calvin–Benson cycle. This...
-
Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells
On glucose restriction, epithelial cells can undergo entosis, a cell-in-cell cannibalistic process, to allow considerable withstanding to this...
-
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
Hepatic glucose and lipid metabolism disorders promote the development and progression of type 2 diabetes mellitus (T2DM), yet the underlying...
-
Metabolic flux analysis: A key methodology for systems biology of metabolism
Genome-wide analyses of mRNA, protein, or metabolite complements of biological systems produce unprecedented data sets. In contrast to such cellular... -
Effect of Biotin Starvation on Gene Expression in Komagataella phaffii Cells
AbstractMethylotrophic yeast Komagataella phaffii is widely used in biotechnology for recombinant protein production. Due to the practical...
-
Understanding the biochemical, physiological, molecular, and synthetic biology approaches towards the development of C4 rice (Oryza sativa L.)
Crop yields must drastically increase to meet the demands of a rapidly increasing global population. One current option being investigated is the...
-
Metabolic engineering of Corynebacterium glutamicum for the efficient production of β-Alanine from glucose
β-Alanine is the only naturally occurring β-type amino acid, with various applications in the pharmaceutical, food, and chemical industries. Given...
-
Improvement of photosynthesis in changing environment: approaches, achievements and prospects
Photosynthesis is responsible for sustained plant productivity and ensures food supply. The change in global climatic patterns affects photosynthesis...
-
Biological Production of Succinic Acid: State of the Art and Future Perspectives
Succinic acid has been extensively used as a precursor for the synthesis of various pharmaceutical- and food-grade chemicals of industrial...