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Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay
BackgroundOvarian cancer is the most lethal gynecologic malignancy in women, and high-grade serous ovarian cancer (HGSOC) is the most common subtype....
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The evaluation of miR-1181 and miR-4314 as serum microRNA biomarkers for epithelial ovarian cancer diagnosis and prognosis
AimEpithelial ovarian cancer (EOC) is the most ominous tumor of gynecological cancers due to its poor early detection rate and unfavorable prognosis....
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The Role of the Human Microbiome in Epithelial Ovarian Cancer
Ovarian cancer is the fifth-leading cause of cancer deaths among women due to the absence of available screening methods to identify early disease....
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Insights into the Microbial Composition of Intratumoral, Reproductive Tract, and Gut Microbiota in Ovarian Cancer Patients
According to the latest global cancer data, ovarian cancer is the deadliest among all gynecological malignant tumors and ranks fifth in terms of...
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EMP1 correlated with cancer progression and immune characteristics in pan-cancer and ovarian cancer
This study examines the prognostic role and immunological relevance of EMP1 (epithelial membrane protein-1) in a pan-cancer analysis, with a focus on...
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Drug-Resistant Epithelial Ovarian Cancer: Current and Future Perspectives
Epithelial ovarian cancer (EOC) is a complex disease with diverse histological subtypes, which, based on the aggressiveness and course of disease...
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The emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early...
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Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness
In ovarian tumors, the omental microenvironment profoundly influences the behavior of cancer cells and sustains the acquisition of stem-like traits,...
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CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α
Ovarian cancer is the most lethal malignancy among gynecologic cancers, and primary and secondary chemotherapy resistance is one of the important...
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STAT3 mediates ECM stiffness-dependent progression in ovarian cancer
The treatment of ovarian cancer remains a medical challenge and its malignant progression is connected with obvious changes in both tissue and cell...
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XTP8 Promotes Ovarian Cancer Progression by Activating AKT/AMPK/mTOR Pathway to Regulate EMT
Ovarian cancer (OC) ranks as the fifth leading cause of cancer-related death in women. The main contributors to the poor prognosis of ovarian cancer...
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ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway
Early detection and effective chemotherapy for ovarian cancer, a serious gynecological malignancy, require further progress. This study aimed to...
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VCAM-1 complements CA-125 in detecting recurrent ovarian cancer
BackgroundClose to three-quarters of ovarian cancer cases are frequently diagnosed at an advanced stage, with more than 70% of them failing to...
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MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway
The incidence rate of develo** ovarian cancer decreases over the years; however, mortality ranks top among malignancies of women, mainly metastasis...
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The senescent mesothelial matrix accentuates colonization by ovarian cancer cells
Ovarian cancer is amongst the most morbid of gynecological malignancies due to its diagnosis at an advanced stage, a transcoelomic mode of...
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Overexpression of MKRN2 Inhibits the Growth of Ovarian Cancer Cells
AbstractOvarian cancer has a high mortality with low five-year survival rates. The role of the E3 ligase Makorin ring finger protein 2 (MKRN2) in...
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Advances in application of circulating tumor DNA in ovarian cancer
Ovarian cancer is the third most common gynecologic cancer worldwide and has the highest mortality rate among gynecologic cancers. Identifying timely...
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MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer
Ovarian cancer is the common cause of cancer-related death in women and is considered the most deadly gynecological cancer. It has been established...
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MiR-590-5p promotes cisplatin resistance via targeting hMSH2 in ovarian cancer
ObjectiveThe mechanisms of ovarian cancer generate chemotherapy resistance are still unclear. This study aimed to explore the role of microRNA...
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Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling
The E3 ubiquitin ligase Tripartite-motif 3 (TRIM3) is known to play a crucial role in tumor suppression in various tumors through different...
