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Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development
Localized sources of morphogens, called signalling centres, play a fundamental role in coordinating tissue growth and cell fate specification during...
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Structural Organization of GABA- and Nitroxidergic Systems of Subfornical Organ in Wistar Rats Postnatal Development
AbstractThe subfornical organ (SFO) is one of the circumventricular organs (CVOs) of the mammalian nervous system responsible for maintaining the...
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Comparison of the effects of cytokinins and chitosan on in vitro seed germination and organ development in radish
Comparative determination of the effects of plant growth regulators and chitosan on several plants suggested a cytokinin-like effect of chitosan in...
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Organ Frame Elements or Free Intercellular Gel-Like Matrix as Necessary Conditions for Building Organ Structures during Regeneration
AbstractOver the past decades, an unimaginably large number of attempts have been made to restore the structure of mammalian organs after injury by...
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Effects of plant growth regulators on in vitro seed germination, organ development and callogenesis in Pancratium maritimum L.
The effects of plant growth regulators (PGRs) on seed germination and organ development in Pancratium maritimum L. (Sea daffodil) were evaluated...
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Identification and expression analysis of the SWEET genes in radish reveal their potential functions in reproductive organ development
BackgroundSugars produced by photosynthesis provide energy for biological activities and the skeletons for macromolecules; they also perform multiple...
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Floral organ-specific proteome profiling of the floral ornamental orchid (Cymbidium goeringii) reveals candidate proteins related to floral organ development
BackgroundCymbidium goeringii , belonging to the Orchidaceae family, is an important ornamental plant with striking petals and lips. Extremely...
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Early embryonic development of Johnston’s organ in the antenna of the desert locust Schistocerca gregaria
Johnston’s organ has been shown to act as an antennal auditory organ across a spectrum of insect species. In the hemimetabolous desert locust Schistoce...
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Advances in understanding the mechanisms of organ abscission in vivo and in vitro plants
Plant organ abscission is a fundamental biological process. and is a stress and evolutionary mechanism formed to adapt to environmental changes due...
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Use and application of organ-on-a-chip platforms in cancer research
Tumors are a major cause of death worldwide, and much effort has been made to develop appropriate anti-tumor therapies. Existing in vitro and in vivo...
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Catecholaminergic Structures of the Rat Subfornical Organ
AbstractDue to the high importance of investigating the subfornical organ and its tissue components and mediator systems, the aim of this work was to...
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Harvesting an Organ
In general, many studies involving the mouse’s brain start with removal of the entire organ first and then select part of the brain to study. In this...
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Targeting tumor suppressor p53 for organ fibrosis therapy
Fibrosis is a reparative and progressive process characterized by abnormal extracellular matrix deposition, contributing to organ dysfunction in...
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A diffusible small-RNA-based Turing system dynamically coordinates organ polarity
The formation of a flat and thin leaf presents a developmentally challenging problem, requiring intricate regulation of adaxial–abaxial (top–bottom)...
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Search progress of pyruvate kinase M2 (PKM2) in organ fibrosis
Fibrosis is characterized by abnormal deposition of the extracellular matrix (ECM), leading to organ structural remodeling and loss of function. The...
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CircRNAs: versatile players and new targets in organ fibrosis
Organ fibrosis can occur in virtually all major organs with relentlessly progressive and irreversible progress, ultimately resulting in organ...
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The genetic architecture of biological age in nine human organ systems
Investigating the genetic underpinnings of human aging is essential for unraveling the etiology of and develo** actionable therapies for chronic...
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Map** single-cell-resolution cell phylogeny reveals cell population dynamics during organ development
Map** the cell phylogeny of a complex multicellular organism relies on somatic mutations accumulated from zygote to adult. Available cell barcoding...
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In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry
BackgroundPicrorhiza kurroa Royle ex Benth. being a rich source of phytochemicals, is a promising high altitude medicinal herb of Himalaya. The...
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Organ-on-chip models for infectious disease research
Research on microbial pathogens has traditionally relied on animal and cell culture models to mimic infection processes in the host. Over recent...
