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EVATOM: an optical, label-free, machine learning assisted embryo health assessment tool
The combination of a good quality embryo and proper maternal health factors promise higher chances of a successful in vitro fertilization (IVF)...
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Imagining the future of optical microscopy: everything, everywhere, all at once
The optical microscope has revolutionized biology since at least the 17 th Century. Since then, it has progressed from a largely observational tool to...
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Flow Sorting–Assisted Optical Map**
Optical map**—a technique that visualizes short sequence motives along DNA molecules of hundred kilobases to megabase in size—has found an... -
Exploring UAS-lidar as a sampling tool for satellite-based AGB estimations in the Miombo woodland of Zambia
To date, only a limited number of studies have utilized remote sensing imagery to estimate aboveground biomass (AGB) in the Miombo ecoregion using...
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Viewing life without labels under optical microscopes
Optical microscopes today have pushed the limits of speed, quality, and observable space in biological specimens revolutionizing how we view life...
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All-optical voltage imaging-guided postsynaptic single-cell transcriptome profiling with Voltage-Seq
Neuronal pathways recruit large postsynaptic populations and maintain connections via distinct postsynaptic response types (PRTs). Until recently,...
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Laser tweezers as a biophotonic tool to investigate the efficacy of living sickle red blood cells in response to optical deformation
A laser tweezer technique based on single and/or dual-laser beams is proposed as a biophotonic tool to trap single cells and investigate their...
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Aptamer-Based Optical Sensors for Food Safety
Food safety is a worldwide problem and ensuring food safety requires strict monitoring of toxins, antibiotics, and bacteria. Thus, sensitive methods... -
Voltage-Seq: all-optical postsynaptic connectome-guided single-cell transcriptomics
Understanding the routing of neuronal information requires the functional characterization of connections. Neuronal projections recruit large...
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Zebrafish xenograft as a tool for the study of colorectal cancer: a review
Colorectal cancer (CRC) is the second leading cause of cancer-related death, mostly due to metastatic disease and the fact that many patients already...
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Dynamic full-field optical coherence tomography module adapted to commercial microscopes allows longitudinal in vitro cell culture study
Dynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as a label-free imaging tool, capable of resolving cell types and...
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Gold Nanoparticles as a Tool to Detect Biomarkers in Osteoarthritis: New Insights
Extensive research over the years has revealed the remarkable potential of gold nanoparticles (AuNPs) for detecting biomarkers in osteoarthritis...
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A neuropsin-based optogenetic tool for precise control of Gq signaling
G q -coupled receptors regulate numerous physiological processes by activating enzymes and inducing intracellular Ca 2+ signals. There is a strong need...
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Forces of Change: Optical Tweezers in Membrane Remodeling Studies
AbstractOptical tweezers allow precise measurement of forces and distances with piconewton and nanometer precision, and have thus been instrumental...
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Adapting the High-Throughput Phenoty** Tool ALPHI® to Potatoes: First Results and Lessons
This study aimed to provide the first results and lessons of the transfer of the ALPHI ® phenoty** tool to potato. The ALPHI ® device is a tractor...
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Second harmonic generation microscopy: a powerful tool for bio-imaging
Second harmonic generation (SHG) microscopy is an important optical imaging technique in a variety of applications. This article describes the...
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Benchmarking MicrobIEM – a user-friendly tool for decontamination of microbiome sequencing data
BackgroundMicrobiome analysis is becoming a standard component in many scientific studies, but also requires extensive quality control of the 16S...
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Debiased ambient vibrations optical coherence elastography to profile cell, organoid and tissue mechanical properties
The role of the mechanical environment in defining tissue function, development and growth has been shown to be fundamental. Assessment of the...
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In vivo characterisation of field pea stem wall thickness using optical coherence tomography
BackgroundModern field pea breeding faces a significant challenge in selecting lines with strong stems that resist lodging. Traditional methods of...
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Super-sectioning with multi-sheet reversible saturable optical fluorescence transitions (RESOLFT) microscopy
Light-sheet fluorescence microscopy is an invaluable tool for four-dimensional biological imaging of multicellular systems due to the rapid...