Search
Search Results
-
Opposing life history strategies allow grass shrimp parasites to avoid a conflict of interest
A conflict of interest occurs when parasites manipulate the behavior of their host in contradictory ways to achieve different goals. In grass shrimp (
-
H3K36 methylation maintains cell identity by regulating opposing lineage programmes
The epigenetic mechanisms that maintain differentiated cell states remain incompletely understood. Here we employed histone mutants to uncover a...
-
Translocation of linearized full-length proteins through an engineered nanopore under opposing electrophoretic force
Nanopores have recently been used to identify and fingerprint proteins. However, because proteins, unlike DNA, do not have a uniform charge, the...
-
Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells
Ubiquitin-specific protease (USP)19 is a deubiquitinating enzyme that regulates the stability and function of multiple proteins, thereby controlling...
-
γδ T cell dichotomy with opposing cytotoxic and wound healing functions in human solid tumors
γδ T cells are important tissue-resident, innate T cells that are critical for tissue homeostasis. γδ cells are associated with positive prognosis in...
-
Elevated nest temperature has opposing effects on host species infested with parasitic nest flies
Environmental factors, such as elevated temperature, can have varying effects on hosts and their parasites, which can have consequences for the net...
-
Opposing directions of stage-specific body shape change in a close relative of C. elegans
BackgroundBody size is a fundamental organismal trait. However, as body size and ecological contexts change across developmental time, evolutionary...
-
HDL and LDL have distinct, opposing effects on LPS-induced brain inflammation
Endotoxemia and sepsis induce neuroinflammation and increase the risk of neurodegenerative disorders although the mechanism by which peripheral...
-
Flextime: Black-and-White Ruffed Lemurs (Varecia variegata) use Opposing Strategies to Counter Resource Scarcity in Fragmented Habitats
Forest fragmentation may lead to substantial declines in food availability for primary consumers, especially presenting a challenge for frugivores,...
-
Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia
The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which...
-
CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis
Despite the emerging evidence on ferroptosis implicated in diverse pathologies, molecular linkage between oxidative inducers and chromatin as...
-
DNA methylation-mediated differential expression of DLX4 isoforms has opposing roles in leukemogenesis
BackgroundPreviously, we reported the expression of DLX4 isoforms ( BP1 and DLX7 ) in myeloid leukemia, but the functional role of DLX4 isoforms...
-
Competition for nitrogen between plants and microorganisms in grasslands: effect of nitrogen application rate and plant acquisition strategy
Several studies have investigated how nitrogen (N) addition changes N competition between focal plant species and soil microorganisms; still, the...
-
Glucocorticoid Effect in Cancer Patients
The use of glucocorticoids is very varied in the context of cancer patients and includes the treatment of symptoms related to cancer, but also the...
-
Opposing functions of β-arrestin 1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3
Although β-arrestins (ARRBs) regulate diverse physiological and pathophysiological processes, their functions and regulation in Parkinson’s disease...
-
Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer
Death domain-associated protein (DAXX) is a complex biological multifunctional protein and is involved in the tumorigenesis and progression of...
-
A two-kinesin mechanism controls neurogenesis in the develo** brain
During the course of brain development, Radial Glial Progenitor (RGP) cells give rise to most of the neurons required for a functional cortex. RGPs...
-
The Effect of Pronase on Mollusk, Leech, and Frog Nerve Ganglia Causes the Formation of Neuron–Neuronal Gap Junctions
Abstract—Using electron microscopy, the effect of pronase on nerve ganglia of a mollusk, leech, and frog was studied for the first time. It was...
-
In Vitro and in Vivo Assays for Testing Retinoids Effect on Intestinal Progenitors’ Lineage Commitments
The intestine consists of epithelial cells surrounded by a complex environment as mesenchymal cells and the gut microbiota. With its impressive stem...
-
European agroforestry has no unequivocal effect on biodiversity: a time-cumulative meta-analysis
BackgroundAgroforestry is a production system combining trees with crops or livestock. It has the potential to increase biodiversity in relation to...
