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Raman spectroscopy-based prediction of ofloxacin concentration in solution using a novel loss function and an improved GA-CNN model
BackgroundA Raman spectroscopy method can quickly and accurately measure the concentration of ofloxacin in solution. This method has the advantages...
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Laccase-loaded magnetic dialdehyde inulin nanoparticles as an efficient heterogeneous natural polymer-based biocatalyst for removal and detoxification of ofloxacin
An efficient heterogeneous natural polymer-based biocatalyst was fabricated through the immobilization of laccase onto dialdehyde inulin (DAI)-coated...
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A Case of Topical Ofloxacin-Induced Otomycosis and Literature Review
The prevalence of fungal otitis externa, or otomycosis, has been increasing in recent decades. Fungi may act as primary pathogens in this condition,...
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Treatment with a neutrophil elastase inhibitor and ofloxacin reduces P. aeruginosa burden in a mouse model of chronic suppurative otitis media
Chronic suppurative otitis media (CSOM) is a widespread, debilitating problem with poorly understood immunology. Here, we assess the host response to...
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Identification of novel single nucleotide variants in the drug resistance mechanism of Mycobacterium tuberculosis isolates by whole-genome analysis
BackgroundTuberculosis (TB) represents a major global health challenge. Drug resistance in Mycobacterium tuberculosis (MTB) poses a substantial...
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Antimicrobial resistance rates of urogenital Mycoplasma hominis and Ureaplasma species before and during the COVID-19 pandemic: results from a Greek survey, 2014 to 2022
The prevalence of antibiotic-resistant urogenital mycoplasmas and ureaplasmas has been gradually increasing over the years, leading to greater...
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Unveiling the critical roles of cellular metabolism suppression in antibiotic tolerance
Metabolic inhibitors are known to exhibit complex interactions with antibiotics in bacteria, potentially acting as antagonists by inducing cell...
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Association of Mutations in gyrA Gene with Resistance to Fluoroquinolones in Clinical Isolates of Multidrug-Resistant Mycobacterium tuberculosis
AbstractThe purpose of the present study was to evaluate the association of mutations inside and outside quinolone-resistance determining region...
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Association of Mutations in gyrA Gene with Resistance to Fluoroquinolones in Clinical Isolates of Multidrug-Resistant Mycobacterium tuberculosis
AbstractThe purpose of the present study was to evaluate the association of mutations inside and outside quinolone-resistance determining region...
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Oral and middle ear delivery of otitis media standard of care antibiotics, but not biofilm-targeted antibodies, alter chinchilla nasopharyngeal and fecal microbiomes
Otitis media (OM) is one of the most globally pervasive pediatric conditions. Translocation of nasopharynx-resident opportunistic pathogens like...
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The Putative Major Facilitator Superfamily (MFS) Protein Named Rv1877 in Mycobacterium tuberculosis Behaves as a Multidrug Efflux Pump
Efflux pumps are one of the major contributors in the intrinsic multidrug resistance of Mycobacterium tuberculosis . These active transporters,...
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Antibiotic resistance, biofilm formation, and virulence genes of Streptococcus agalactiae serotypes of Indian origin
BackgroundGroup B Streptococcus (GBS) is a causative agent of various infections in newborns, immunocompromised (especially diabetic) non-pregnant...
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Isolation, characterization, virulence genes, antimicrobial resistant genes, and antibiotic susceptibility pattern of Vibrio parahaemolyticus in relation to AHPND from shrimp farms in coastal districts of Tamil Nadu
Vibrio parahaemolyticus is a gram-negative motile bacterium inhabiting marine, estuarine, and coastal environments. It is a critical aquatic pathogen...
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Prevalence of antibiotic-resistant bacterial strains in wastewater streams: molecular characterization and relative abundance
Bacteria from wastewater discharged to the sewerage near three hospitals of Islamabad, Rawalpindi, and Faisalabad were examined for resistance to the...
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Phthirus pubis (Anoplura: Phthiridae) infestation of the palpebral margin and scalp hair in an infant
This paper reports a rare case of Phthirus pubis infestation of the palpebral margin and scalp hair in an 8-month-old infant. Under the microscope,...
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Microbiological and molecular studies on a multidrug-resistant Pseudomonas aeruginosa from a liver transplant patient with urinary tract infection in Egypt
BackgroundPseudomonas aeruginosa is an opportunistic pathogen responsible for complicated UTIs and exhibits high antibiotic resistance, leading to...
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A new probiotic Lactobacillus plantarum strain isolated from traditional dairy together with nanochitosan particles shows the synergistic effect on aflatoxin B1 detoxification
The present study aimed to evaluate the effects of new Lactobacillus plantarum strain isolated from dairy products as well as chitosan nanoparticles...
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A novel enrofloxacin-degrading fungus, Humicola sp. KC0924g, isolated from the rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.
A novel enrofloxacin-degrading fungus was isolated from a rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.. The isolate,...
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Harnessing the saline soil-inhabiting bacteria for antagonistic, antibiotic resistance, and plant growth-promoting attributes
Biological control of soil-borne plant infections is sorely needed since they are challenging to treat with conventional fungicides. This fundamental...
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Pleiotropic actions of phenothiazine drugs are detrimental to Gram-negative bacterial persister cells
Bacterial persister cells are temporarily tolerant to bactericidal antibiotics but are not necessarily dormant and may exhibit physiological...
