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Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis
Noroviruses are the leading cause of severe childhood diarrhea and foodborne disease worldwide. While they are a major cause of disease in all age...
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A non-human primate model for human norovirus infection
Norovirus infection can cause gastrointestinal disease in humans. Development of therapies and vaccines against norovirus have been limited by the...
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Epidemiological Characteristics of Norovirus Outbreaks in Shenyang from 2017 to 2021
Norovirus is one of the leading causes of acute gastroenteritis outbreaks worldwide. This study aimed to identify the epidemiological characteristics...
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Detection of Viral Agents Causing Gastroenteritis by Multiplex PCR Method in Patients; Norovirus, Rotavirus, Adenovirus, Astrovirus, Sapovirus
Acute viral gastroenteritis may lead hospitalization and death in individuals with underlying health conditions such as immunosuppression....
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Chemokine CCL6 Plays Key Role in the Inhibitory Effect of Vitamin A on Norovirus Infection
Norovirus (NoV) is the most common viral cause of acute gastroenteritis worldwide. Vitamin A has demonstrated the potential to protect against...
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Comparative study of the geographical spread of genogroup II porcine norovirus and human norovirus
Livestock pigs and porcine norovirus could be candidate tools for future studies on the geographic isolation of norovirus. In this study, we provide...
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Evaluation of heat treatment for inactivation of norovirus genogroup II in foods
The effective food processing technology is a key step in eliminating human noroviruses in foods mainly due to their stability in diverse...
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Identification and genetic characterization of a minor norovirus genotype, GIX.1[GII.P15], from China
BackgroundHuman noroviruses, single-stranded RNA viruses in the family Caliciviridae , are a leading cause of nonbacterial acute gastroenteritis in...
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Benchmarking different approaches for Norovirus genome assembly in metagenome samples
BackgroundGenome assembly of viruses with high mutation rates, such as Norovirus and other RNA viruses, or from metagenome samples, poses a challenge...
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Age-associated features of norovirus infection analysed in mice
Norovirus (NoV) is the leading global cause of viral gastroenteritis. Young children bear the highest burden of disease and play a key role in viral...
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Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions
Norovirus capsids are icosahedral particles composed of 90 dimers of the major capsid protein VP1. The C-terminus of the VP1 proteins forms a...
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Norovirus GII and astrovirus in shellfish from a mangrove region in Cananéia, Brazil: molecular detection and characterization
In recent years, annual cases of gastroenteritis have been reported in the world at high rates, suggesting an association with the consumption of...
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Norovirus detection in water samples at the level of single virus copies per microliter using a smartphone-based fluorescence microscope
Norovirus is a widespread public health threat and has a very low infectious dose. This protocol presents the extremely sensitive mobile detection of...
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EHEC O111:H8 strain and norovirus GII.4 Sydney [P16] causing an outbreak in a daycare center, Brazil, 2019
BackgroundThis study describes the investigation of an outbreak of diarrhea, hemorrhagic colitis (HC), and hemolytic uremic syndrome (HUS) at a...
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Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors
We have recently established that human norovirus (HuNoV) replicates efficiently in zebrafish larvae after inoculation of a clinical sample into the...
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rprimer: an R/bioconductor package for design of degenerate oligos for sequence variable viruses
BackgroundThis paper presents a new R/Bioconductor package, rprimer, for design of degenerate oligos and PCR assays for sequence variable viruses. A...
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Foodborne Viral Pathogen Big Data: Genomic Analysis
Despite advances in hygienic measures and vaccine development, foodborne viral diseases remain frequent. Common foodborne viruses such as norovirus,...