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Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants
Due to the continuous evolution of SARS-CoV-2, the Omicron variant has emerged and exhibits severe immune evasion. The high number of mutations at...
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A neutralizing monoclonal antibody–based blocking ELISA to detect bovine herpesvirus 1 and vaccination efficacy
AbstractInfections caused by bovine herpesvirus 1 (BoHV-1) remain a serious global issue to the health and welfare of the bovine industry. Monitoring...
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Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2
SARS-CoV-2 variants may threaten the effectiveness of vaccines and antivirals to mitigate serious COVID-19 disease. This is of most concern in...
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Impact of Covishield Vaccination in Terms of SARS CoV-2 Neutralizing Antibody Expression
The vaccination efficacy can indirectly be assessed through the quantification of neutralizing antibodies. Very few data are available on Covishield...
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Structural and functional analysis of a potent human neutralizing antibody against enterovirus A71
Enterovirus A71 (EV-A71) causes major outbreaks of hand, foot, and mouth disease (HFMD) in many countries, most frequently affecting children, and a...
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Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), especially the latest Omicron, have exhibited severe...
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Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination
The current SARS-CoV-2 variants strikingly evade all authorized monoclonal antibodies and threaten the efficacy of serum-neutralizing activity...
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Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection
Elucidating the dynamics of the neutralizing antibody (nAb) response in coronavirus disease 2019 (COVID-19) convalescents is crucial in controlling...
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A canine-derived chimeric antibody with high neutralizing activity against canine parvovirus-2
Canine parvovirus-2 (CPV-2) infection causes serious multisystemic disease in dogs and many animal species worldwide. Previously, a monoclonal...
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Neutralizing antibody: a savior in the Covid-19 disease
Coronavirus outbreak was declared a pandemic by World Health Organization (WHO) in March 2020. The pandemic has led to a devastating loss of life. It...
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The dynamics of neutralizing antibodies against SARS-CoV-2 in cats naturally exposed to virus reveals an increase in antibody activity after re-infection
Severe Acute Respiratory Syndrome Coronavirus 2 is the causative agent of Coronavirus Disease 2019 in humans. To date, little is known about the...
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Impaired neutralizing antibody response to COVID-19 mRNA vaccines in cancer patients
There is currently a critical need to determine the efficacy of SARS-CoV-2 vaccination for immunocompromised patients. In this study, we determined...
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Differential neutralizing antibody responses elicited by CoronaVac and BNT162b2 against SARS-CoV-2 Lambda in Chile
SARS-CoV-2 variant Lambda was dominant in several South American countries, including Chile. To ascertain the efficacy of local vaccination efforts,...
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Neutralizing anti-diphtheria toxin scFv produced by phage display
BackgroundDiphtheria can be prevented by vaccination, but some epidemics occur in several places, and diphtheria’s threat is considerable....
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Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern
COVID-19 vaccine design and vaccination rollout need to take into account a detailed understanding of antibody durability and cross-neutralizing...
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Engineered clinical-grade mesenchymal stromal cells combating SARS-CoV-2 omicron variants by secreting effective neutralizing antibodies
BackgroundThe emergence of SARS-CoV-2 becomes life-threatening for the older and immunocompromised individuals, whereas limited treatment is...
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Broad strategies for neutralizing SARS-CoV-2 and other human coronaviruses with monoclonal antibodies
Antibody therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have been approved in many countries, with most being developed based on...
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Neutralizing antibody response against subcutaneously injected bacteriophages in rabbit model
Bacteriophage therapy is currently experiencing a renaissance. Therapeutic efficacy of bacteriophages depends on phage-bacterial and phage-host...
