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Maternal and neonatal factors affecting neonatal behaviour in West African Dwarf goats
There is a paucity of information on neonatal behaviour of tropical livestock species despite its adaptive value. One hundred and ninety West African...
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Maternal circadian rhythm disruption affects neonatal inflammation via metabolic reprograming of myeloid cells
Disruption of circadian rhythm during pregnancy produces adverse health outcomes in offspring; however, the role of maternal circadian rhythms in the...
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Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice
In the adult sensory cortex, increases in neural activity elicited by sensory stimulation usually drive vasodilation mediated by neurovascular...
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The PD-1–PD-L1 pathway maintains an immunosuppressive environment essential for neonatal heart regeneration
The adult mouse heart responds to injury by scarring with consequent loss of contractile function, whereas the neonatal heart possesses the ability...
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The neonatal southern white rhinoceros ovary contains oogonia in germ cell nests
The northern white rhinoceros is functionally extinct with only two females left. Establishing methods to culture ovarian tissues, follicles, and...
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Evaluating the probiotic effects of spraying lactiplantibacillus plantarum P-8 in neonatal piglets
BackgroundGut microbes play an important role in the growth and health of neonatal piglets. Probiotics can promote the healthy growth of neonatal...
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Tudor-SN promotes cardiomyocyte proliferation and neonatal heart regeneration through regulating the phosphorylation of YAP
BackgroundThe neonatal mammalian heart exhibits considerable regenerative potential following injury through cardiomyocyte proliferation, whereas...
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Interfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages
Necrotizing enterocolitis (NEC) is a life-threatening, inflammatory disease affecting premature infants with intestinal necrosis, but the mechanism...
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Neonatal GABAergic transmission primes vestibular gating of output for adult spatial navigation
GABAergic interneurons are poised with the capacity to shape circuit output via inhibitory gating. How early in the development of medial vestibular...
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Chromatin accessibility and H3K9me3 landscapes reveal long-term epigenetic effects of fetal-neonatal iron deficiency in rat hippocampus
BackgroundIron deficiency (ID) during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive...
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Variants in FREM1 and trisomy 18 identified in a neonatal progeria patient
BackgroundNeonatal progeroid disorders are rare disorders with clinical features including low body mass index, proptosis, aged and dysmorphic facial...
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Machine Learning Algorithms to Predict Healthcare Associated Infections in a Neonatal Intensive Care Unit
One of the most common causes of mortality and morbidity in neonatal intensive care units (NICU) are healthcare associated infections (HAIs). HAIs in...
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A neonatal rat model of pulmonary vein stenosis
ObjectivesPulmonary vein stenosis (PVS), one of the most challenging clinical problems in congenital heart disease, leads to secondary pulmonary...
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YAP induces a neonatal-like pro-renewal niche in the adult heart
After myocardial infarction (MI), mammalian hearts do not regenerate, and the microenvironment is disrupted. Hippo signaling loss of function with...
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N6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic-ischemic neonatal rats
Hypoxic-ischemic brain damage (HIBD) can result in significant global rates of neonatal death or permanent neurological disability....
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Neonatal Brain Temperature Monitoring Based on Broadband Near-Infrared Spectroscopy
We present here the initial development of a novel algorithm based on broadband near-infrared spectroscopy (bNIRS) data to estimate the changes in...
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Proteomic analysis of neonatal mouse hearts shows PKA functions as a cardiomyocyte replication regulator
The ability of the adult mammalian heart to regenerate can save the cardiac muscle from a loss of function caused by injury. Cardiomyocyte...
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3-(Bromoacetyl) coumarin is a potential therapeutic agent against neonatal sepsis-associated Pseudomonas extremorientalis
Neonatal sepsis is a severe bacterial infection that can lead to life-threatening complications in newborns. Pseudomonas extremorientalis is a...
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Structural and functional asymmetry of the neonatal cerebral cortex
Features of brain asymmetry have been implicated in a broad range of cognitive processes; however, their origins are still poorly understood. Here we...
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Structural and functional changes in rat uterus induced by neonatal androgenization
Fetal or neonatal androgen exposure has a programming effect on ovarian function inducing a polycystic ovarian syndrome-like condition. Its effects...
