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Showing 1-20 of 82 results
  1. The protein-protein interaction ontology: for better representing and capturing the biological context of protein interaction

    Background

    With the rapid increase in the amount of Protein-Protein Interaction (PPI) data, the establishment of an event-centered PPI ontology that...

    Mansheng Li, Qiang He, ... Yun** Zhu in BMC Genomics
    Article Open access 16 November 2021
  2. CEDAR OnDemand: a browser extension to generate ontology-based scientific metadata

    Background

    Public biomedical data repositories often provide web-based interfaces to collect experimental metadata. However, these interfaces...

    Syed Ahmad Chan Bukhari, Marcos Martínez-Romero, ... Steven H. Kleinstein in BMC Bioinformatics
    Article Open access 16 July 2018
  3. SIFR annotator: ontology-based semantic annotation of French biomedical text and clinical notes

    Background

    Despite a wide adoption of English in science, a significant amount of biomedical data are produced in other languages, such as French. Yet...

    Andon Tchechmedjiev, Amine Abdaoui, ... Clement Jonquet in BMC Bioinformatics
    Article Open access 06 November 2018
  4. Development of the International Classification of Diseases Ontology (ICDO) and its application for COVID-19 diagnostic data analysis

    Background

    The 10th and 9th revisions of the International Statistical Classification of Diseases and Related Health Problems (ICD10 and ICD9) have...

    Ling Wan, Justin Song, ... Yongqun He in BMC Bioinformatics
    Article Open access 18 October 2021
  5. Conceiving an application ontology to model patient human papillomavirus vaccine counseling for dialogue management

    Background

    In the United States and parts of the world, the human papillomavirus vaccine uptake is below the prescribed coverage rate for the...

    Muhammad Amith, Kirk Roberts, Cui Tao in BMC Bioinformatics
    Article Open access 23 December 2019
  6. The cell line ontology-based representation, integration and analysis of cell lines used in China

    Background

    The Chinese National Infrastructure of Cell Line stores and distributes cell lines for biomedical research in China. This study aims to...

    Hongjie Pan, **aocui Bian, ... Yuqin Liu in BMC Bioinformatics
    Article Open access 25 April 2019
  7. OMeta: an ontology-based, data-driven metadata tracking system

    Background

    The development of high-throughput sequencing and analysis has accelerated multi-omics studies of thousands of microbial species,...

    Indresh Singh, Mehmet Kuscuoglu, ... Karen E. Nelson in BMC Bioinformatics
    Article Open access 07 January 2019
  8. PGxO and PGxLOD: a reconciliation of pharmacogenomic knowledge of various provenances, enabling further comparison

    Background

    Pharmacogenomics (PGx) studies how genomic variations impact variations in drug response phenotypes. Knowledge in pharmacogenomics is...

    Pierre Monnin, Joël Legrand, ... Adrien Coulet in BMC Bioinformatics
    Article Open access 18 April 2019
  9. Mining data and metadata from the gene expression omnibus

    Publicly available gene expression datasets deposited in the Gene Expression Omnibus (GEO) are growing at an accelerating rate. Such datasets hold...

    Zichen Wang, Alexander Lachmann, Avi Ma’ayan in Biophysical Reviews
    Article Open access 29 December 2018
  10. Semantic Integration and Enrichment of Heterogeneous Biological Databases

    Biological databases are growing at an exponential rate, currently being among the major producers of Big Data, almost on par with commercial...
    Ana Claudia Sima, Kurt Stockinger, ... Manuel Gil in Evolutionary Genomics
    Protocol Open access 2019
  11. Systematics for types and effects of DNA variations

    Background

    Numerous different types of variations can occur in DNA and have diverse effects and consequences. The Variation Ontology (VariO) was...

    Mauno Vihinen in BMC Genomics
    Article Open access 28 December 2018
  12. The Ontology of Biological and Clinical Statistics (OBCS)-based statistical method standardization and meta-analysis of host responses to yellow fever vaccines

    Background

    The community-based Ontology of Biological and Clinical Statistics (OBCS) represents and standardizes biological and clinical data and...

    Jie Zheng, Huan Li, ... Yongqun He in Quantitative Biology
    Article 23 November 2017
  13. Semantic Technologies and Bio-Ontologies

    As information available through data repositories constantly grows, the need for automated mechanisms for linking, querying, and sharing data has...
    Fernando Gutierrez in Bioinformatics in MicroRNA Research
    Protocol 2017
  14. FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining

    Background

    For automated reading of scientific publications to extract useful information about molecular mechanisms it is critical that genes,...

    John A. Bachman, Benjamin M. Gyori, Peter K. Sorger in BMC Bioinformatics
    Article Open access 28 June 2018
  15. Ontology-based systematic representation and analysis of traditional Chinese drugs against rheumatism

    Background

    Rheumatism represents any disease condition marked with inflammation and pain in the joints, muscles, or connective tissues. Many...

    Qing** Liu, Jiahao Wang, ... Yongqun He in BMC Systems Biology
    Article Open access 21 December 2017
  16. Endophytic Microbes as a Novel Source for Producing Anticancer Compounds as Multidrug Resistance Modulators

    Endophytes are a range of microorganisms which inhabit the plant tissues, establishing an association with their hosts during a period for nearly or...
    Chapter 2018
  17. Data management and best practice for plant science

    Sabina Leonelli, Robert P. Davey, ... Ruth Bastow in Nature Plants
    Article 06 June 2017
  18. The Interaction Network Ontology-supported modeling and mining of complex interactions represented with multiple keywords in biomedical literature

    Background

    The Interaction Network Ontology (INO) logically represents biological interactions, pathways, and networks. INO has been demonstrated to...

    Arzucan Özgür, Junguk Hur, Yongqun He in BioData Mining
    Article Open access 19 December 2016
  19. NOBLE – Flexible concept recognition for large-scale biomedical natural language processing

    Background

    Natural language processing (NLP) applications are increasingly important in biomedical data analysis, knowledge engineering, and decision...

    Eugene Tseytlin, Kevin Mitchell, ... Rebecca S. Jacobson in BMC Bioinformatics
    Article Open access 14 January 2016
  20. Representing and querying disease networks using graph databases

    Background

    Systems biology experiments generate large volumes of data of multiple modalities and this information presents a challenge for integration...

    Artem Lysenko, Irina A. Roznovăţ, ... Charles Auffray in BioData Mining
    Article Open access 25 July 2016
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