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  1. Markers of imminent myocardial infarction

    Myocardial infarction is a leading cause of death globally but is notoriously difficult to predict. We aimed to identify biomarkers of an imminent...

    Stefan Gustafsson, Erik Lampa, ... Johan Sundström in Nature Cardiovascular Research
    Article Open access 12 February 2024
  2. The roles of Th cells in myocardial infarction

    Myocardial infarction, commonly known as a heart attack, is a serious condition caused by the abrupt stoppage of blood flow to a part of the heart,...

    Jun Liu, Feila Liu, ... Panke Cheng in Cell Death Discovery
    Article Open access 15 June 2024
  3. Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling

    Immune response plays a crucial role in post-myocardial infarction (MI) myocardial remodeling. Neogenin (Neo1), a multifunctional transmembrane...

    Jishou Zhang, Yao Xu, ... Menglong Wang in Cellular and Molecular Life Sciences
    Article 12 October 2023
  4. Post translational modifications of connexin 43 in ventricular arrhythmias after myocardial infarction

    Ventricular arrhythmias are the leading cause of sudden cardiac death in patients after myocardial infarction (MI). Connexin43 (Cx43) is the most...

    Fan Yang, **ao-Lu Zhang, ... Ru-**ng Wang in Molecular Biology Reports
    Article 23 February 2024
  5. CCR2 imaging in human ST-segment elevation myocardial infarction

    Among the diverse populations of myeloid cells that reside within the healthy and diseased heart, C-C chemokine receptor type 2 (CCR2) is...

    Kory J. Lavine, Deborah Sultan, ... Yongjian Liu in Nature Cardiovascular Research
    Article 21 September 2023
  6. Pyroptosis and mitochondrial function participated in miR-654-3p-protected against myocardial infarction

    Myocardial infarction (MI) is one of the leading causes of heart failure with highly complicated pathogeneses. miR-654-3p has been recognized as a...

    Chan Wu, **ao-Cheng Zhang, ... Gang Li in Cell Death & Disease
    Article Open access 04 June 2024
  7. Cardiac biomarkers and detection methods for myocardial infarction

    Background

    A significant heart attack known as a myocardial infarction (MI) occurs when the blood supply to the heart is suddenly interrupted, harming...

    Sang Young Kim, **-Pyo Lee, ... Yang-Hoon Kim in Molecular & Cellular Toxicology
    Article 10 September 2022
  8. Serum lipidomics reveals phosphatidylethanolamine and phosphatidylcholine disorders in patients with myocardial infarction and post-myocardial infarction-heart failure

    Background

    Myocardial infarction (MI) and post-MI-heart failure (pMIHF) are a major cause of death worldwide, however, the underlying mechanisms of...

    Jidong Rong, Tianmu He, ... Bei Shi in Lipids in Health and Disease
    Article Open access 20 May 2023
  9. TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53

    Efferocytosis and metabolic reprogramming of macrophages play crucial roles in myocardial infarction (MI) repair. TREM2 has been proven to...

    Shiyu Gong, Ming Zhai, ... Wenhui Peng in Cell Death & Differentiation
    Article Open access 05 January 2024
  10. Anshen Shumai Decoction inhibits post-infarction inflammation and myocardial remodeling through suppression of the p38 MAPK/c-FOS/EGR1 pathway

    Anshen Shumai Decoction (ASSMD) is traditionally employed to manage coronary artery disease arrhythmias. Its protective efficacy against myocardial...

    Jianfeng Wang, **aolei Ye, Yanqin Wang in Journal of Molecular Histology
    Article 14 June 2024
  11. Modeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids

    Heart disease involves irreversible myocardial injury that leads to high morbidity and mortality rates. Numerous cell-based cardiac in vitro models...

    Myeong** Song, Da Bin Choi, ... Dong-Hun Woo in Cell Death & Disease
    Article Open access 01 May 2024
  12. Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarction

    Early and prompt reperfusion therapy has markedly improved the survival rates among patients enduring myocardial infarction (MI). Nonetheless, the...

    Wenjie Zuo, Renhua Sun, ... Genshan Ma in Cellular & Molecular Biology Letters
    Article Open access 19 October 2023
  13. MicroRNA-322-5p targeting Smurf2 regulates the TGF-β/Smad pathway to protect cardiac function and inhibit myocardial infarction

    Acute coronary artery blockage leads to acute myocardial infarction (AMI). Cardiomyocytes are terminally differentiated cells that rarely divide....

    Li** Guo, Ke Li, ... Haixiong Wang in Human Cell
    Article 24 April 2024
  14. M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction

    Background

    Myocardial infarction (MI) is a major cause of mortality and morbidity worldwide. The intercellular communication in post-infarction...

    Hongzhou Guo, Zeya Li, ... Rongchong Huang in Biology Direct
    Article Open access 06 June 2024
  15. Inflammation in myocardial infarction: roles of mesenchymal stem cells and their secretome

    Inflammation plays crucial roles in the regulation of pathophysiological processes involved in injury, repair and remodeling of the infarcted heart;...

    Lianbo Shao, Ying Shen, ... Junjie Yang in Cell Death Discovery
    Article Open access 09 November 2022
  16. LncRNA CCRR maintains Ca2+ homeostasis against myocardial infarction through the FTO-SERCA2a pathway

    Cardiac conduction regulatory RNA (CCRR) has been documented as an antiarrhythmic lncRNA in our earlier investigation. This study aimed to evaluate...

    Hua Yang, Lina Xuan, ... Lihua Sun in Science China Life Sciences
    Article 16 May 2024
  17. Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction

    Acute myocardial infarction has long been the leading cause of death in coronary heart disease, which is characterized by irreversible cardiomyocyte...

    Yuchang Liu, Minrui Wang, ... Chunxiang Zhang in Cell Communication and Signaling
    Article Open access 14 August 2023
  18. Development of a thick and functional human adipose-derived stem cell tissue sheet for myocardial infarction repair in rat hearts

    Background

    Heart failure (HF) is a major cause of death worldwide. The most effective treatment for HF is heart transplantation, but its use is...

    **gbo Zhang, Junjun Li, ... Shigeru Miyagawa in Stem Cell Research & Therapy
    Article Open access 20 December 2023
  19. ATR1 A1166C (rs5186), FII G20210A (rs1799963), FV G1691A (rs6025), FXIII 97G > T (rs11466016) and MTHFR A1298C (rs1801131) polymorphisms and the risk of ST-elevation myocardial infarction in young Mexican individuals

    Background

    Previous studies had identified genetic variants associated with Myocardial Infarction, but results are inconclusive. We examined the...

    Irma Isordia-Salas, David Santiago-Germán, ... Alfredo Leaños-Miranda in Molecular Biology Reports
    Article 25 January 2024
  20. ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis

    Background

    Acute myocardial infarction is a major health problem and is the leading cause of death worldwide. Myocardial apoptosis induced by...

    Tingting Wang, Tao Li, ... Yanjie Guo in Biology Direct
    Article Open access 27 February 2023
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