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MIWE: detecting the critical states of complex biological systems by the mutual information weighted entropy
Complex biological systems often undergo sudden qualitative changes during their dynamic evolution. These critical transitions are typically...
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Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information
BackgroundCorrelation metrics are widely utilized in genomics analysis and often implemented with little regard to assumptions of normality,...
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CPMI: comprehensive neighborhood-based perturbed mutual information for identifying critical states of complex biological processes
BackgroundThere exists a critical transition or tip** point during the complex biological process. Such critical transition is usually accompanied...
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Filtering ASVs/OTUs via mutual information-based microbiome network analysis
Microbial communities are widely studied using high-throughput sequencing techniques, such as 16S rRNA gene sequencing. These techniques have...
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Gene regulation network inference using k-nearest neighbor-based mutual information estimation: revisiting an old DREAM
BackgroundA cell exhibits a variety of responses to internal and external cues. These responses are possible, in part, due to the presence of an...
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ScInfoVAE: interpretable dimensional reduction of single cell transcription data with variational autoencoders and extended mutual information regularization
Single-cell RNA-sequencing (scRNA-seq) data can serve as a good indicator of cell-to-cell heterogeneity and can aid in the study of cell growth by...
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CoMI: consensus mutual information for tissue-specific gene signatures
BackgroundThe gene signatures have been considered as a promising early diagnosis and prognostic analysis to identify disease subtypes and to...
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Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis
BackgroundFinding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly...
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First record of mutual allogrooming in wild northern red muntjac Muntiacus Vaginalis
We report the first record of mutual allogrooming in free-ranging wild northern red muntjac ( Muntiacus vaginalis ) from dense tropical forests of...
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Predation dynamics and mutual interference among ladybird beetles in managing Diaspis echinocacti (Bouché) infestation on Opuntia spp
Diaspis echinocacti (Bouché) poses a significant threat to Opuntia spp. worldwide, highlighting the critical need for effective control measures....
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Sparse estimation of mutual information landscapes quantifies information transmission through cellular biochemical reaction networks
Measuring information transmission from stimulus to response is useful for evaluating the signaling fidelity of biochemical reaction networks (BRNs)...
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Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction
MicroRNA (miRNA) serves as a pivotal regulator of numerous cellular processes, and the identification of miRNA-disease associations (MDAs) is crucial...
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FCMEDriver: Identifying Cancer Driver Gene by Combining Mutual Exclusivity of Embedded Features and Optimized Mutation Frequency Score
Efficiently identifying cancer driver genes is critical to drug design, cancer diagnosis and treatment. Current unsupervised cancer driver gene...
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Mutual induced-fit mechanism drives binding between intrinsically disordered Bim and cryptic binding site of Bcl-xL
The intrinsically disordered region (IDR) of Bim binds to the flexible cryptic site of Bcl-xL, a pro-survival protein involved in cancer progression...
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Separate and Mutual Effects of BIRB796 and Bortezomib on pHsp27 and Viability of U87MG Glioma Cells
AbstractHsp27 phosphorylation is associated with many pathways in glioma, such as tumor cell proliferation and apoptosis inhibition. The aim of this...
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Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth
Glioblastoma (GBM) is a highly vascular malignant brain tumor that overexpresses vascular endothelial growth factor (VEGF) and phosphofructokinase 1...
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A thermophilic chemolithoautotrophic bacterial consortium suggests a mutual relationship between bacteria in extreme oligotrophic environments
A thermophilic, chemolithoautotrophic, and aerobic microbial consortium (termed carbonitroflex) growing in a nutrient-poor medium and an atmosphere...
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A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide
BackgroundRhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation....
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Multivariate information theory uncovers synergistic subsystems of the human cerebral cortex
One of the most well-established tools for modeling the brain is the functional connectivity network, which is constructed from pairs of interacting...
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An implementation of integrated information theory in resting-state fMRI
Integrated Information Theory was developed to explain and quantify consciousness, arguing that conscious systems consist of elements that are...
