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Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer
Breast cancer is one of the prevailing cancers globally, with a high mortality rate. Metastatic breast cancer (MBC) is an advanced stage of cancer,...
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A molecular network map of orexin-orexin receptor signaling system
Orexins are excitatory neuropeptides, which are predominantly associated with feeding behavior, sleep-wake cycle and energy homeostasis. The...
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scRNA-seq generates a molecular map of emerging cell subtypes after sciatic nerve injury in rats
Patients with peripheral nerve injury, viral infection or metabolic disorder often suffer neuropathic pain due to inadequate pharmacological options...
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Molecular phylogenies map to biogeography better than morphological ones
Phylogenetic relationships are inferred principally from two classes of data: morphological and molecular. Currently, most phylogenies of extant taxa...
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Isoform-specific RNA structure determination using Nano-DMS-MaP
RNA structure determination is essential to understand how RNA carries out its diverse biological functions. In cells, RNA isoforms are readily...
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The pan-genome of Mycobacterium avium subsp. paratuberculosis (Map) confirms ancestral lineage and reveals gene rearrangements within Map Type S
BackgroundTo date genomic studies on Map have concentrated on Type C strains with only a few Type S strains included for comparison. In this study...
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A network map of GDNF/RET signaling pathway in physiological and pathological conditions
Glial cell line-derived neurotrophic factor (GDNF) signals through a multi-component receptor system predominantly consisting of...
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A network map of macrophage-stimulating protein (MSP) signaling
Macrophage-stimulating protein (MSP), a serum-derived growth factor belonging to the plasminogen-related kringle domain family, is mainly produced by...
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Molecular map** of drought-responsive QTLs during the reproductive stage of rice using a GBS (genoty**-by-sequencing) based SNP linkage map
BackgroundIn rice, drought stress at reproductive stage drastically reduces yield, which in turn hampers farmer’s efforts towards crop production....
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Evaluation of homozygosity levels of onion (Allium cepa L.) inbred lines using molecular markers evenly distributed in a high-resolution linkage map
Onion ( Allium cepa L.) is a cross-pollinated crop with severe inbreeding depression. Inbred breeding lines are thus commonly maintained through...
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Genetic Map Construction Using F2 and RIL/DH Map** Population
Genetic map** is the determination of the position and relative genetic distance between genes or molecular markers in the chromosomes of a...
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High-density linkage map and QTL map for yield and yield components of sorghum recombinant inbreed lines developed from Gambella × Sorcoll 163/07 using GBS
Sorghum ( Sorghum bicolor (L.) Moench), a cereal of economic importance, ensures food and fodder security for millions of rural families in the...
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SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19
Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has been declared a pandemic by...
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QTL Map** and Genetic Map for the Ornamental Sunflower in China
Quantitative trait locus (QTL) map** and genetic map are of great significance for ornamental sunflowers in China. In this study, a total of 956.50...
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Chem-map profiles drug binding to chromatin in cells
Characterizing drug–target engagement is essential to understand how small molecules influence cellular functions. Here we present Chem-map for in...
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Molecular Markers
A molecular marker is defined as a particular segment of DNA that is representative of the differences at the genome analysis. Molecular markers are...
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Molecular Linkage Map**: Map Construction and Map** of Genes/QTLs
Jute is considered as one of the major fibre crops next to cotton and is distributed throughout the tropical and sub-tropical regions of the world....
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Construction of a high-density genetic linkage map and QTL analysis using an interspecific F1 population in pistachio
Pistachio ( Pistacia vera L.) is one of the commercially important cultivated nut tree species in Turkey. Pistachio nuts have many beneficial...
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A network map of cytoskeleton-associated protein 4 (CKAP4) mediated signaling pathway in cancer
Cytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is...
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Genetic linkage map construction and QTL analysis for plant height in proso millet (Panicum miliaceum L.)
Key messageA genetic linkage map representing proso millet genome was constructed with SSR markers, and a major QTL corresponding to plant height was...
