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Biotransformation approach to produce rare ginsenosides F1, compound Mc1, and Rd2 from major ginsenosides
The stems and leaves of Panax notoginseng contain high saponins, but they are often discarded as agricultural waste. In this study, the predominant...
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HPLC-MS Analysis of Ginsenosides in Morphogenic Cell Cultures of Ginseng (Panax ginseng C.A. Meyer)
AbstractThe composition of triterpene glycosides in different in vitro tissues of cell lines (PgR–rhizogenic and PgG–hemogenic) and roots of ginseng...
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Discovery of enzymes to biotransform ginsenoside Rd into ginsenosides F2 and CK using metagenomics and genomic mining
Ginsenosides are the main active components of ginseng, including many types and different contents. Among them, minor ginsenosides have better...
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Enhancement of biotransformation of ginsenosides in white ginseng roots by aerobic co-cultivation of Bacillus subtilis and Trichoderma reesei
In the present work, the biotransformation of ginsenosides in white ginseng roots was innovatively investigated using the aerobic fermentation by the...
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Pharmacological properties of ginsenosides in inflammation-derived cancers
Ginseng is commonly used as an herbal medicine for improvement of life quality. It is also used as a supplemental medication with anti-cancer drugs...
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Isolation, characterisation and genome analysis of a novel ginsenosides hydrolysing bacterium Ginsengibacter hankyongi gen. nov., sp. nov. isolated from soil
A novel yellow-pigmented bacterial strain (designated BR5-29 T ), was isolated and its taxonomy was studied. Phylogenetic study based on the 16S rRNA...
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High-density immobilization of a ginsenoside-transforming β-glucosidase for enhanced food-grade production of minor ginsenosides
Use of recombinant glycosidases is a promising approach for the production of minor ginsenosides, e.g., Compound K (CK) and F 1 , which have potential...
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Production of ginsenoside compound K from American ginseng extract by fed-batch culture of Aspergillus tubingensis
Compound K (C-K), one of the most bioactive ginsenoside, is produced by hydrolyzing the glycoside moieties of protopanaxadiol (PPD)-type glycosylated...
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Biocatalytic strategies for the production of ginsenosides using glycosidase: current state and perspectives
AbstractPanax ginseng is a traditional Chinese medicine with significant pharmaceutical effects and broad application. Rare ginsenosides with high...
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Genes and Regulatory Mechanisms for Ginsenoside Biosynthesis
Panax ginseng is a medicinal plant belonging to the Araliaceae family. Ginseng is known as the king of oriental medicine, which has been practiced...
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Production of ginsenoside compound K by microbial cell factory using synthetic biology-based strategy: a review
Ginsenoside compound K (CK) is a major intestinal bacterial metabolite of the protopanaxadiol-type ginsenoside family that can be absorbed in the...
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Metabolic Dynamics and Ginsenoside Biosynthesis
Panax ginseng, a medicinally important perennial herb, has been widely used as the medicinal plant in South East Asian countries such as Korea,...
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Enzymatic upcycling of wild-simulated ginseng leaves for enhancing biological activities and compound K
Compound K (CK), a ginsenoside with high bioavailability, is present at low levels in wild-simulated ginseng leaves (WSGL). WSGL contains the CK...
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Identification and RNAi-based gene silencing of a novel UDP-glycosyltransferase from Panax quinquefolius
Panax quinquefolius ( P. quinquefolius ) has been used as medicine for thousands of years in Asia. Ginsenosides are major pharmacological active...
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Gut Microbiome for Ginseng Medicine
In the past few decades, using traditional Chinese medicines (TCMs), including Panax ginseng as pharmaceutical, nutraceutical, and healthcare...
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Isolation and Characterization of Sphingomonas telluris, Sphingomonas caseinilyticus Isolated from Wet Land Soil
Two novel bacterial strains, designated as SM33 T and NSE70-1 T , were isolated from wet soil in South Korea. To get the taxonomic positions, the...
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Chemical components of ginseng, their biotransformation products and their potential as treatment of hypertension
Ginseng is an ancient perennial herb belonging to the family Araliaceae and genus Panax which has been used for medical therapeutics for thousands of...
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Stereum hirsutum (Willd.) Pers.; Stereum rugosum Pers. - STEREACEAE
Stereum hirsutum (Willd.) Pers.; Stereum rugosum Pers. - STEREACEAE
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Temperature-Linked Constraints and Plant Protection Responses
Extreme (high or low) temperatures in environment exert stresses against plants leading to disturbances of (i) fluidity or rigidity states of cell...
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Enzymatic biotransformation of Rb3 from the leaves of Panax notoginseng to ginsenoside rd by a recombinant β-xylosidase from Thermoascus aurantiacus
Given the important pharmacological activity of ginsenoside Rd but its low content in plants, the production of Rd by enzymatic transformation is of...
