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The non-mevalonate pathway requires a delicate balance of intermediates to maximize terpene production
AbstractTerpenes are valuable industrial chemicals whose demands are increasingly being met by bioengineering microbes such as E. coli . Although the...
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A systematic review of 1-Deoxy-D-xylulose-5-phosphate synthase in terpenoid biosynthesis in plants
1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is the first rate-limiting enzyme involved in the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway for...
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Hyperaccumulation of fucoxanthin by enhancing methylerythritol phosphate pathway in Phaeodactylum tricornutum
AbstractThe established human health benefits of carotenoids along with the contemporary consumption of natural carotenoids bring the necessity to...
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Strain improvement for enhanced erythritol production by Moniliella pollinis Mutant-58 using jaggery as a cost-effective substrate
Erythritol has been produced by various microorganisms including Yarrowia , Moniliella , Aureobasidium , and Candida strains. Due to its relatively high...
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Isolation of 4-hydroxy 3-methyl 2-butenyl 4-diphosphate reductase (ApHDR) gene of methyl erythritol diphosphate (MEP) pathway, in silico analysis and differential tissue specific ApHDR expression in Andrographis paniculata (Burm. f) Nees
The full length Andrographis paniculate 4-hydroxy 3-methyl 2-butenyl 4-diphosphate reductase ( ApHDR ) gene of MEP pathway was isolated for the first...
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Metabolite profiling and transcriptomic analyses demonstrate the effects of biocontrol agents on alkaloid accumulation in Fritillaria thunbergii
BackgroundDuring Fritillaria thunbergii planting, pests and diseases usually invade the plant, resulting in reduced yield and quality. Previous...
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Sandalwood Fragrance Pathway and Its Engineering for Sustainable Production of High-Value Santalols
The essential oil extracted from the Santalum genus, known as sandalwood oil is one of the most valuable plant-derived secondary metabolites. It is...
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Crenobacter oryzisoli sp. nov., a novel phosphate-solubilizing bacterium isolated from the paddy soil
Two Gram-staining-negative, facultative anaerobic, rod-shaped and phosphate-solubilizing strains designated SG2303 T and SG2305, were isolated from...
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Full-length transcriptome profiling of Acanthopanax gracilistylus provides new insight into the kaurenoic acid biosynthesis pathway
Acanthopanax gracilistylus is a deciduous plant in the family Araliaceae, which is commonly used in Chinese herbal medicine, as the root bark has...
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Dynamics of annatto pigment synthesis and accumulation in seeds of Bixa orellana L. revealed by integrated chemical, anatomical, and RNA-Seq analyses
Bixin is a commercially valuable apocarotenoid pigment found in the seed aril of Bixa orellana . The dynamics and regulation of its biosynthesis and...
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Phytohormone-Mediated Regulation of Heat Stress Response in Plants
Heat stress is one of the most devastating abiotic stresses that cause substantial yield loss around the world. Heat stress induces excessive...
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The phosphorylated pathway of serine biosynthesis affects sperm, embryo, and sporophyte development, and metabolism in Marchantia polymorpha
Serine metabolism is involved in various biological processes. Here we investigate primary functions of the phosphorylated pathway of serine...
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LiCOI1 mediates the biosynthesis of monoterpenes induced by methyl jasmonate in Lilium ‘Siberia’
As a volatile hormone signal, methyl jasmonate (MeJA) can regulate the biosynthesis of secondary metabolites. But in floral fragrance, the effect and...
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Plants against cancer: towards green Taxol production through pathway discovery and metabolic engineering
The diversity of plant natural products presents a rich resource for accelerating drug discovery and addressing pressing human health issues....
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Functional Genomics Approaches for Gene Discovery Related to Terpenoid Indole Alkaloid Biosynthetic Pathway in Catharanthus roseus
Catharanthus roseus is one of the most explored medicinal plants owing to its immense potential to synthesize various terpenoid indole alkaloids...
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Sclareol and linalyl acetate are produced by glandular trichomes through the MEP pathway
Sclareol, an antifungal specialized metabolite produced by clary sage, Salvia sclarea , is the starting plant natural molecule used for the...
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Intraspecific divergence in essential oil content, composition and genes expression patterns of monoterpene synthesis in Origanum vulgare subsp. vulgare and subsp. gracile under salinity stress
BackgroundOregano ( Origanum vulgare L.), one of the important medicinal plants in the world, has valuable pharmacological compounds with...
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The eukaryotic MEP-pathway genes are evolutionarily conserved and originated from Chlaymidia and cyanobacteria
BackgroundIsoprenoids are the most ancient and essential class of metabolites produced in all organisms, either via mevalonate (MVA)-and/or...
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Growth condition controls on G-93 parameters of isoprene emission from tropical trees
Despite its major role in global isoprene emission, information on the environmental control of isoprene emission from tropical trees has remained...
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In Vitro Production of Terpenoids
Plants produce diverse groups of secondary metabolites (SMs); terpenoids are one such large group of SMs. Terpenoids are found commonly in related...