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Construction of Small-Insert and Large-Insert Metagenomic Libraries
The vast majority of the Earth’s biological diversity are hidden in uncultured and yet uncharacterized microbial genomes. The construction of...
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Metagenomic Data Analysis
This volume describes different sequencing methods, pipelines and tools for metagenome data analyses. Chapters guide readers through quality control...
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Adversarial and variational autoencoders improve metagenomic binning
Assembly of reads from metagenomic samples is a hard problem, often resulting in highly fragmented genome assemblies. Metagenomic binning allows us...
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Interactive Web-Based Services for Metagenomic Data Analysis and Comparisons
Recently, sequencing technologies have become readily available, and scientists are more motivated to conduct metagenomic research to unveil the...
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Activity-Based Screening of Metagenomic Fosmid Libraries for Hydrogen-Uptake Enzymes
Here, we outline how to identify hydrogenase enzymes from metagenomic fosmid libraries through an activity-based screening approach. A metagenomic...
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cgMSI: pathogen detection within species from nanopore metagenomic sequencing data
BackgroundMetagenomic sequencing is an unbiased approach that can potentially detect all the known and unidentified strains in pathogen detection....
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Recent Advances in Metagenomic Approaches, Applications, and Challenges
Advances in metagenomics analysis with the advent of next-generation sequencing have extended our knowledge of microbial communities as compared to...
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Integration of polygenic and gut metagenomic risk prediction for common diseases
Multiomics has shown promise in noninvasive risk profiling and early detection of various common diseases. In the present study, in a prospective...
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In Silico Analysis of Phylogeny, Structure, and Function of Flavohemoproteins from Metagenomic Data
AbstractIn this study, flavohemoproteins from protist, bacterial and fungal sources as well those available in metagenome data have been...
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aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
Analysis of microbial data from archaeological samples is a growing field with great potential for understanding ancient environments, lifestyles,...
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Construction and Functional Screening of Metagenomic Libraries for D-Stereospecific Amidases and Their Catalytic Promiscuity
AbstractMetagenomic fosmid libraries were prepared from soil and water samples collected from diverse places. Clones in the range of (1.1–2.8) × 10 3 ...
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Uncovering microbiomes of the rice phyllosphere using long-read metagenomic sequencing
The plant microbiome is crucial for plant growth, yet many important questions remain, such as the identification of specific bacterial species in...
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Bioremediation of Heavy Metals by Metagenomic Approaches
Deposition of heavy metals and other contaminating materials in the environment is a ceaseless and inescapable process. Bioaccumulation of heavy...
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Automatic disease prediction from human gut metagenomic data using boosting GraphSAGE
BackgroundThe human microbiome plays a critical role in maintaining human health. Due to the recent advances in high-throughput sequencing...
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Mora: abundance aware metagenomic read re-assignment for disentangling similar strains
BackgroundTaxonomic classification of reads obtained by metagenomic sequencing is often a first step for understanding a microbial community, but...
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Impact of microbial genome completeness on metagenomic functional inference
Inferring the functional capabilities of bacteria from metagenome-assembled genomes (MAGs) is becoming a central process in microbiology. Here we...
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Precision enzyme discovery through targeted mining of metagenomic data
Metagenomics has opened new avenues for exploring the genetic potential of uncultured microorganisms, which may serve as promising sources of enzymes...
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Metagenomic Screening of a Novel PET Esterase via In Vitro Expression System
Metagenomic screening is a widely applied biotechnological approach for screening of novel industrial enzymes. The traditional method of metagenomic...
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An in-depth evaluation of metagenomic classifiers for soil microbiomes
BackgroundRecent endeavours in metagenomics, exemplified by projects such as the human microbiome project and TARA Oceans, have illuminated the...
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Recent Trends in Metagenomic Approaches in Environmental Cleanup
Metagenomic approaches are being widely used to detect all culturable and unculturable microbes present in environmental samples in a time-saving and...