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Quartet metabolite reference materials for inter-laboratory proficiency test and data integration of metabolomics profiling
BackgroundVarious laboratory-developed metabolomic methods lead to big challenges in inter-laboratory comparability and effective integration of...
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Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia
IntroductionLongitudinal biomarkers in patients with community-acquired pneumonia (CAP) may help in monitoring of disease progression and treatment...
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Development of metabolome extraction strategy for metabolite profiling of skin tissue
IntroductionChanges in skin phenotypic characteristics are based on skin tissue. The study of the metabolic changes in skin tissue can help...
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Antimicrobial and antioxidant activity and GC-MS metabolite profiling of cyanobacteria in the tersakan stream (Amasya, Türkiye)
Cyanobacteria are photosynthetic prokaryotes with biologically active metabolites. The present work investigated the antimicrobial and antioxidant...
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Advanced high-resolution chromatographic strategies for efficient isolation of natural products from complex biological matrices: from metabolite profiling to pure chemical entities
The isolation of pure compounds from extracts represents a key step common to all investigations of natural product (NP) research. Isolation methods...
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Stable isotope-assisted metabolite profiling reveals new insights into L-tryptophan chemotrophic metabolism of Rubrivivax benzoatilyticus
Anoxygenic photosynthetic bacteria (APB) are metabolically versatile, capable of surviving with an extended range of carbon and nitrogen sources....
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Metabolite profiling of tubers of an early- and a late-maturing potato line and their grafts
IntroductionEarliness of tuberisation and the quality of potato tubers are important traits in potato breeding. The qualitative traits rely on the...
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Genome-wide characterization and metabolite profiling of Cyathus olla: insights into the biosynthesis of medicinal compounds
Cyathus olla , belonging to the genus Cyathus within the order Agaricales, is renowned for its bird's nest-like fruiting bodies and has been utilized...
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Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer
Identifying metabolites and delineating their immune-regulatory contribution in the tumor microenvironment is an area of intense study. Interrogating...
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Mass spectrometry-based metabolite profiling reveals functional seasonal shifts in the metabolome of Zygophyllum dumosum Boiss and its relation to environmental conditions
Main conclusionA multi-year study of perennial Z. dumosum shows a consistent seasonal pattern in the changes of petiole metabolism, involving mainly...
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Comparative metabolite analysis of Piper sarmentosum organs approached by LC–MS-based metabolic profiling
Piper sarmentosum Roxb. (Piperaceae) is a traditional medicinal and food plant widely distributed in the tropical and subtropical regions of Asia,...
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Metabolite-Based Genome-Wide Association Studies of Large-Scale Metabolome Analysis to Illustrate Alterations in the Metabolite Landscape of Plants upon Responses to Stresses
Given that anthropogenic activities are evoking a profound effect on the climate resulting in more extreme events such as severe drought and heat... -
Identification of key genes controlling monoterpene biosynthesis of Citral-type Cinnamomum bodinieri Levl. Based on transcriptome and metabolite profiling
The citral-type is the most common chemotype in Cinnamomum bodinieri Levl ( C. bodinieri ), which has been widely used in the daily necessities,...
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Tissue- and time-dependent metabolite profiles during early grain development under normal and high night-time temperature conditions
BackgroundWheat grain development in the first few days after pollination determines the number of endosperm cells that influence grain yield...
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Protein–Metabolite Interactions Shape Cellular Metabolism and Physiology
Protein–metabolite interactions regulate many important cellular processes but still remain understudied. Recent technological advancements are... -
Metabolite profiling of abalone (Haliotis iris) energy metabolism: a Chatham Islands case study
IntroductionThe Chatham Islands has some of the most prized black-footed abalone ( Haliotis iris ) beds in New Zealand. This well-managed fishery...
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Metabolomic profiling of human bladder tissue extracts
IntroductionBladder cancer is a common malignancy affecting the urinary tract and effective biomarkers and for which monitoring therapeutic...
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Comparative transcriptome and metabolite profiling reveal diverse pattern of CYP-TS gene expression during corosolic acid biosynthesis in Lagerstroemia speciosa (L.) Pers
Key messageExtensive leaf transcriptome profiling and differential gene expression analysis of field grown and elicited shoot cultures of L. speciosa...
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Untargeted metabolite profiling of Enterococcus villorum SB2, isolated from the vagina of pregnant women, by HR-LCMS
Enterococcus bacteria are studied in various sectors including fermentation, food and dairy industries,as well as studied for their probiotic...
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Statistical considerations and database limitations in NMR-based metabolic profiling studies
IntroductionInterpretation and analysis of NMR-based metabolic profiling studies is limited by substantially incomplete commercial and academic...