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  1. Quartet metabolite reference materials for inter-laboratory proficiency test and data integration of metabolomics profiling

    Background

    Various laboratory-developed metabolomic methods lead to big challenges in inter-laboratory comparability and effective integration of...

    Naixin Zhang, Qiaochu Chen, ... Yuanting Zheng in Genome Biology
    Article Open access 24 January 2024
  2. Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia

    Introduction

    Longitudinal biomarkers in patients with community-acquired pneumonia (CAP) may help in monitoring of disease progression and treatment...

    Ilona den Hartog, Laura B. Zwep, ... J. G. Coen van Hasselt in Metabolomics
    Article Open access 05 March 2024
  3. Development of metabolome extraction strategy for metabolite profiling of skin tissue

    Introduction

    Changes in skin phenotypic characteristics are based on skin tissue. The study of the metabolic changes in skin tissue can help...

    Ting Bu, Sooah Kim in Metabolomics
    Article 29 April 2024
  4. Antimicrobial and antioxidant activity and GC-MS metabolite profiling of cyanobacteria in the tersakan stream (Amasya, Türkiye)

    Cyanobacteria are photosynthetic prokaryotes with biologically active metabolites. The present work investigated the antimicrobial and antioxidant...

    Emine Çelikoğlu, Meral Yılmaz Cankılıç, Önder İdil in Biologia
    Article 10 June 2024
  5. Advanced high-resolution chromatographic strategies for efficient isolation of natural products from complex biological matrices: from metabolite profiling to pure chemical entities

    The isolation of pure compounds from extracts represents a key step common to all investigations of natural product (NP) research. Isolation methods...

    Emerson Ferreira Queiroz, Davy Guillarme, Jean-Luc Wolfender in Phytochemistry Reviews
    Article Open access 06 May 2024
  6. Stable isotope-assisted metabolite profiling reveals new insights into L-tryptophan chemotrophic metabolism of Rubrivivax benzoatilyticus

    Anoxygenic photosynthetic bacteria (APB) are metabolically versatile, capable of surviving with an extended range of carbon and nitrogen sources....

    Shabbir Ahmad, Mujahid Mohammed, ... Chintalapati Venkata Ramana in World Journal of Microbiology and Biotechnology
    Article 14 February 2023
  7. Metabolite profiling of tubers of an early- and a late-maturing potato line and their grafts

    Introduction

    Earliness of tuberisation and the quality of potato tubers are important traits in potato breeding. The qualitative traits rely on the...

    Vanda Villányi, Orsolya Kinga Gondor, Zsófia Bánfalvi in Metabolomics
    Article Open access 05 November 2022
  8. Genome-wide characterization and metabolite profiling of Cyathus olla: insights into the biosynthesis of medicinal compounds

    Cyathus olla , belonging to the genus Cyathus within the order Agaricales, is renowned for its bird's nest-like fruiting bodies and has been utilized...

    **uchao **e, Ling Zhao, ... Jianzhao Qi in BMC Genomics
    Article Open access 19 June 2024
  9. Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer

    Identifying metabolites and delineating their immune-regulatory contribution in the tumor microenvironment is an area of intense study. Interrogating...

    Marisa K. Kilgour, Sarah MacPherson, ... Julian J. Lum in Nature Protocols
    Article 19 August 2022
  10. Mass spectrometry-based metabolite profiling reveals functional seasonal shifts in the metabolome of Zygophyllum dumosum Boiss and its relation to environmental conditions

    Main conclusion

    A multi-year study of perennial Z. dumosum shows a consistent seasonal pattern in the changes of petiole metabolism, involving mainly...

    Noga Sikron-Persi, Gila Granot, ... Aaron Fait in Planta
    Article Open access 03 June 2023
  11. Comparative metabolite analysis of Piper sarmentosum organs approached by LC–MS-based metabolic profiling

    Piper sarmentosum Roxb. (Piperaceae) is a traditional medicinal and food plant widely distributed in the tropical and subtropical regions of Asia,...

    Ismail Ware, Katrin Franke, ... Ludger A. Wessjohann in Natural Products and Bioprospecting
    Article Open access 14 May 2024
  12. Metabolite-Based Genome-Wide Association Studies of Large-Scale Metabolome Analysis to Illustrate Alterations in the Metabolite Landscape of Plants upon Responses to Stresses

    Given that anthropogenic activities are evoking a profound effect on the climate resulting in more extreme events such as severe drought and heat...
    Feng Zhu, Mustafa Bulut, ... Alisdair R. Fernie in Plant Abiotic Stress Signaling
    Protocol 2023
  13. Identification of key genes controlling monoterpene biosynthesis of Citral-type Cinnamomum bodinieri Levl. Based on transcriptome and metabolite profiling

    The citral-type is the most common chemotype in Cinnamomum bodinieri Levl ( C. bodinieri ), which has been widely used in the daily necessities,...

    Qingyan Ling, Beihong Zhang, ... Yuanqiu Liu in BMC Genomics
    Article Open access 31 May 2024
  14. Tissue- and time-dependent metabolite profiles during early grain development under normal and high night-time temperature conditions

    Background

    Wheat grain development in the first few days after pollination determines the number of endosperm cells that influence grain yield...

    Nathan Abshire, Andrew L. Hauck, ... Toshihiro Obata in BMC Plant Biology
    Article Open access 18 June 2024
  15. Protein–Metabolite Interactions Shape Cellular Metabolism and Physiology

    Protein–metabolite interactions regulate many important cellular processes but still remain understudied. Recent technological advancements are...
    Prathibha Muralidhara, Jennifer C. Ewald in Cell-Wide Identification of Metabolite-Protein Interactions
    Protocol 2023
  16. Metabolite profiling of abalone (Haliotis iris) energy metabolism: a Chatham Islands case study

    Introduction

    The Chatham Islands has some of the most prized black-footed abalone ( Haliotis iris ) beds in New Zealand. This well-managed fishery...

    Leonie Venter, Andrea C. Alfaro, ... Jeremie Zander Lindeque in Metabolomics
    Article Open access 13 July 2022
  17. Metabolomic profiling of human bladder tissue extracts

    Introduction

    Bladder cancer is a common malignancy affecting the urinary tract and effective biomarkers and for which monitoring therapeutic...

    Krzysztof Ossoliński, Tomasz Ruman, ... Joanna Nizioł in Metabolomics
    Article 24 January 2024
  18. Comparative transcriptome and metabolite profiling reveal diverse pattern of CYP-TS gene expression during corosolic acid biosynthesis in Lagerstroemia speciosa (L.) Pers

    Key message

    Extensive leaf transcriptome profiling and differential gene expression analysis of field grown and elicited shoot cultures of L. speciosa...

    Karuna Surendran, Siya Pradeep, Padmesh Pandaram Pillai in Plant Cell Reports
    Article 20 April 2024
  19. Untargeted metabolite profiling of Enterococcus villorum SB2, isolated from the vagina of pregnant women, by HR-LCMS

    Enterococcus bacteria are studied in various sectors including fermentation, food and dairy industries,as well as studied for their probiotic...

    Shivani Singh Gaur, Uday S. Annapure in World Journal of Microbiology and Biotechnology
    Article 07 September 2022
  20. Statistical considerations and database limitations in NMR-based metabolic profiling studies

    Introduction

    Interpretation and analysis of NMR-based metabolic profiling studies is limited by substantially incomplete commercial and academic...

    Imani L. Ross, Julie A. Beardslee, ... Michael A. Kennedy in Metabolomics
    Article 28 June 2023
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