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Enzyme Identification and Screening: Activity-Based Methods
Methods for the identification and characterization of “ideal” enzymes for industrial use in the field of biotechnology have developed rapidly in... -
Synthesis, Molecular Docking, Some Metabolic Enzyme Inhibition Properties, and Antioxidant Activity Studies of 1,4-Naphthoquinones
AbstractObjective: Naphthoquinones are compounds that are common in nature which have biological activity depending on the attachment of new...
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Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0
Genome-scale metabolic models (GEMs) are computational representations that enable mathematical exploration of metabolic behaviors within cellular...
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Change in Microbial Metabolic Quotient Under Biochar Amendment Was Associated with Soil Organic Carbon Quality, Microbial Community Composition, and Enzyme Activity in Bulk and Rhizosphere Soils in an Acid Rice Paddy
Decreases in soil microbial metabolic quotient ( q CO 2 ) have been frequently observed under biochar amendment; however, the potential driving factors...
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Relationship among Changes in Nonstructural Carbohydrate Content, Metabolic Enzyme Activity, and Growth Rhythm in Lycoris radiata
AbstractLycoris radiata (L'Hér.) Herb. is a perennial bulbous flower with high ornamental value. However, the uncertainty of itsflowering seriously...
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Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities
BackgroundMicrobial communities are important drivers of global biogeochemical cycles, xenobiotic detoxification, as well as organic matter...
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Metabolic Adaptations and Functional Activity of Macrophages in Homeostasis and Inflammation
AbstractIn recent years, the role of cellular metabolism in immunity has come into the focus of many studies. These processes form a basis for the...
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Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer
The glycolytic enzyme lactate dehydrogenase A (LDHA) is frequently overexpressed in cancer, which promotes glycolysis and cancer. The oncogenic...
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The Protection of Enzyme Activity for the Preparation of Humanized Polymerized Hemoglobin-Superoxide Dismutase-Catalase-Carbonic Anhydrase
AbstractThis work finds suitable enzyme activity protectants to improve the recovery rate of enzyme activity in the preparation of human polymerized...
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Extracellular Enzyme Activity and Stoichiometry Across Vegetated and Non-Vegetated Coastal Ecosystems
The conversion of organic matter by extracellular enzymes can reveal important insights into carbon and nutrient cycling. The activity and...
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Metabolic Control Analysis
Metabolic Control Analysis (MCA) is a theoretical framework for investigating and understanding control and regulation of metabolism. In particular,... -
Exploring the competitive dynamic enzyme allocation scheme through enzyme cost minimization
Enzyme allocation (or synthesis) is a crucial microbial trait that mediates soil biogeochemical cycles and their responses to climate change....
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Legume-potato rotation affects soil physicochemical properties, enzyme activity, and rhizosphere metabolism in continuous potato crop**
BackgroundContinuous crop** can reduce soil quality and affect rhizosphere metabolism, ultimately reducing crop yield. Crop rotation can mitigate...
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Enzyme Kinetics
In this chapter, you will learn the fundamental concepts of chemical and enzyme catalysis as well as kinetics such as the lock and key and the... -
Measuring Niche-Associated Metabolic Activity in Planktonic and Biofilm Bacteria
Most pathobionts of the respiratory tract form biofilms during asymptomatic colonization to survive and persist in this niche. Environmental changes... -
Soil Enzyme Activity in Natural and Plowed Catenas as Parameters of Physiological State of Microbial Communities
AbstractThe study of soil microbial biomass and enzymatic activity of natural and anthropogenically transformed ecosystems was carried out. The...
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A comparative analyses of lipid ratios representing desaturase enzyme activity between preterm and term infants within the first ten weeks of life
BackgroundDesaturase enzymes play a key role in several pathways including biosynthesis of poly- and mono- unsaturated fatty acids (PUFAs, MUFA). In...
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Evaluating the Effects of Water-Nitrogen Interactions on Carbon and Nitrogen Accumulation As Well As Related Metabolic Enzymes Activity in Autumn Maize
Water deficiency and nitrogen shortage are key factors limiting agricultural development. Therefore, it is particularly important to clarify the...
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Synthetic and biological surfactant effects on freshwater biofilm community composition and metabolic activity
AbstractSurfactants are used to control microbial biofilms in industrial and medical settings. Their known toxicity on aquatic biota, and their...
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In vitro enzyme inhibitory effects of green and brown Australian seaweeds and potential impact on metabolic syndrome
Hypertension, type-2-diabetes (T2D) and obesity are contributory risk factors for the development of metabolic syndrome. Peptides, polyphenols and...