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Showing 1-20 of 8,578 results
  1. RLFDDA: a meta-path based graph representation learning model for drug–disease association prediction

    Background

    Drug repositioning is a very important task that provides critical information for exploring the potential efficacy of drugs. Yet...

    Meng-Long Zhang, Bo-Wei Zhao, ... Lun Hu in BMC Bioinformatics
    Article Open access 01 December 2022
  2. Dry season residual straw reduces nitrous oxide emissions during rice season in upland-paddy rotation systems by inhibiting soil denitrification

    The mechanism by which residual straw incorporation affects nitrous oxide (N 2 O) and carbon dioxide equivalent (CO 2 -eq) emissions throughout the rice...

    Tao Wang, Chengyang Ji, ... Wanjun Ren in Biology and Fertility of Soils
    Article 29 June 2024
  3. Computational drug repositioning using meta-path-based semantic network analysis

    Background

    Drug repositioning is a promising and efficient way to discover new indications for existing drugs, which holds the great potential for...

    Zhen Tian, Zhixia Teng, ... Maozu Guo in BMC Systems Biology
    Article Open access 31 December 2018
  4. Habitat connectivity of threatened ungulate species in a native savanna landscape of northern South America

    The native savanna ecosystem of the Orinoquia region is the habitat of 50% of the wild ungulate species reported for Colombia. Over the last...

    Federico Mosquera-Guerra, Sebastián Barreto, ... Dolors Armenteras-Pascual in Mammalian Biology
    Article Open access 22 April 2024
  5. Predicting MiRNA-disease associations by multiple meta-paths fusion graph embedding model

    Background

    Many studies prove that miRNAs have significant roles in diagnosing and treating complex human diseases. However, conventional biological...

    Lei Zhang, Bailong Liu, ... Jiyong An in BMC Bioinformatics
    Article Open access 21 October 2020
  6. Combined embedding model for MiRNA-disease association prediction

    Background

    Cumulative evidence from biological experiments has confirmed that miRNAs have significant roles to diagnose and treat complex diseases....

    Bailong Liu, **aoyan Zhu, ... Zhengwei Li in BMC Bioinformatics
    Article Open access 25 March 2021
  7. Metapath-Based Deep Convolutional Neural Network for Predicting miRNA-Target Association on Heterogeneous Network

    Predicting the interactions between microRNAs (miRNAs) and target genes is of great significance for understanding the regulatory mechanism of miRNA...

    Jiawei Luo, Yaoting Bao, ... Cong Shen in Interdisciplinary Sciences: Computational Life Sciences
    Article 25 June 2021
  8. Tract-specific statistics based on diffusion-weighted probabilistic tractography

    Diffusion-weighted neuroimaging approaches provide rich evidence for estimating the structural integrity of white matter in vivo, but typically do...

    Andrew T. Reid, Julia A. Camilleri, ... Simon B. Eickhoff in Communications Biology
    Article Open access 17 February 2022
  9. NEDD: a network embedding based method for predicting drug-disease associations

    Background

    Drug discovery is known for the large amount of money and time it consumes and the high risk it takes. Drug repositioning has, therefore,...

    Renyi Zhou, Zhangli Lu, ... Min Li in BMC Bioinformatics
    Article Open access 17 September 2020
  10. Self-perceptions as mechanisms of achievement inequality: evidence across 70 countries

    Children from lower socioeconomic status (SES) backgrounds tend to have more negative self-perceptions. More negative self-perceptions are often...

    Sarah I. Hofer, Jörg-Henrik Heine, ... Eddie Brummelman in npj Science of Learning
    Article Open access 11 January 2024
  11. Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host–microbiota and other multi-omic interactions

    We present Transkingdom Network Analysis (TkNA), a unique causal-inference analytical framework that offers a holistic view of biological systems by...

    Nolan K. Newman, Matthew S. Macovsky, ... Andrey Morgun in Nature Protocols
    Article 12 March 2024
  12. Evaluating and improving the representation of bacterial contents in long-read metagenome assemblies

    Background

    In the metagenomic assembly of a microbial community, abundant species are often thought to assemble well given their deeper sequencing...

    **aowen Feng, Heng Li in Genome Biology
    Article Open access 11 April 2024
  13. A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications

    Disease–disease relationships (e.g., disease comorbidities) play crucial roles in pathobiological manifestations of diseases and personalized...

    Shuting **, **angxiang Zeng, ... Feixiong Cheng in npj Systems Biology and Applications
    Article Open access 13 November 2019
  14. A heterogeneous graph convolutional attention network method for classification of autism spectrum disorder

    Background

    Autism spectrum disorder (ASD) is a serious developmental disorder of the brain. Recently, various deep learning methods based on...

    Lizhen Shao, Cong Fu, Xunying Chen in BMC Bioinformatics
    Article Open access 27 September 2023
  15. Coral reef potential connectivity in the southwest Indian Ocean

    The tropical southwest Indian Ocean is a coral biodiversity hotspot, with remote reefs physically connected by larval dispersal through eddies and a...

    Noam S. Vogt-Vincent, April J. Burt, ... Helen L. Johnson in Coral Reefs
    Article Open access 24 June 2024
  16. AMPFLDAP: Adaptive Message Passing and Feature Fusion on Heterogeneous Network for LncRNA-Disease Associations Prediction

    Exploration of the intricate connections between long noncoding RNA (lncRNA) and diseases, referred to as lncRNA-disease associations (LDAs), plays a...

    Yansen Su, **g**g Liu, ... Chunhou Zheng in Interdisciplinary Sciences: Computational Life Sciences
    Article 06 April 2024
  17. Navigation System for Autonomous Agricultural Vehicles for Indoor Farms

    Simultaneous Localization and Map** (SLAM) is a fundamental technology in autonomous driving and refers to realizing autonomation and intelligent...
    Wu Shiran, Tofael Ahamed in IoT and AI in Agriculture
    Chapter 2024
  18. Metabolic Potential of Serratia sp. 22S for Chlorphenoxyacetic Acids Conversion

    Abstract

    A bacterial strain 22S belonging to the genus Serratia was isolated from soil samples contaminated with chemical production wastes. The...

    N. V. Zharikova, E. I. Zhurenko, ... G. E. Aktuganov in Applied Biochemistry and Microbiology
    Article 01 February 2024
  19. Predicting drug–protein interactions by preserving the graph information of multi source data

    Examining potential drug–target interactions (DTIs) is a pivotal component of drug discovery and repurposing. Recently, there has been a significant...

    Jiahao Wei, Linzhang Lu, Tie Shen in BMC Bioinformatics
    Article Open access 04 January 2024
  20. Canopy gap impacts on soil organic carbon and nutrient dynamic: a meta-analysis

    Key message

    The forest canopy gaps, formed by natural or anthropogenic factors, have been found to reduce soil carbon content and increase nutrient...

    Ran Tong, Biyong Ji, ... Tonggui Wu in Annals of Forest Science
    Article Open access 04 March 2024
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