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The Janus-faced functions of Apolipoproteins L in membrane dynamics
The functions of human Apolipoproteins L (APOLs) are poorly understood, but involve diverse activities like lysis of bloodstream trypanosomes and...
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Curvature sensing lipid dynamics in a mitochondrial inner membrane model
Membrane curvature is essential for many cellular structures and processes, and factors such as leaflet asymmetry, lipid composition, and proteins...
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Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes
The dynamics of cellular membrane tension and its role in mechanosensing, which is the ability of cells to respond to physical stimuli, remain...
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Visualization of Exo- and Endocytosis Membrane Dynamics with Super-Resolution STED Microscopy
Recent advances in stimulated emission depletion (STED) microscopy offer an unparalleled avenue to study membrane dynamics of exo- and endocytosis,...
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Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach
Cholesterol is the most representative sterol present in membranes of higher eukaryotes, and is the end product of a long and multistep biosynthetic...
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Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease
Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively associated with highly curved and prominent membrane structures. It is...
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Regulating membrane curvature
Membranes of living cells are subject to a variety of shape changes. Membrane deformation is essential for cell division, locomotion, organelle...
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A Molecular Dynamics Study of Antimicrobial Peptide Interactions with the Lipopolysaccharides of the Outer Bacterial Membrane
With rising bacterial resistance, antimicrobial peptides (AMPs) have been widely investigated as potential antibacterial molecules to replace...
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Membrane Dynamics and Remodelling in Response to the Action of the Membrane-Damaging Pore-Forming Toxins
Pore-forming protein toxins (PFTs) represent a diverse class of membrane-damaging proteins that are produced by a wide variety of organisms....
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Membrane Lipids Methods and Protocols
This detailed book explores examples of current in vitro and in silicotechniques that are at the forefront of lipid membrane research today....
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Predicting Membrane-Active Peptide Dynamics in Fluidic Lipid Membranes
Understanding the interactions between peptides and lipid membranes could not only accelerate the development of antimicrobial peptides as treatments...
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Theta oscillations represent collective dynamics of multineuronal membrane potentials of murine hippocampal pyramidal cells
Theta (θ) oscillations are one of the characteristic local field potentials (LFPs) in the hippocampus that emerge during spatial navigation,...
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Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration
During cell migration and polarization, numerous signal transduction and cytoskeletal components self-organize to generate localized protrusions....
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Recent Advances in Modeling Membrane β-Barrel Proteins Using Molecular Dynamics Simulations: From Their Lipid Environments to Their Assemblies
Spurred by advances in AI-driven modeling and experimental methods, molecular dynamics simulations are now acting as a platform to integrate these...
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Monitoring cell membrane recycling dynamics of proteins using whole-cell fluorescence recovery after photobleaching of pH-sensitive genetic tags
Population behavior of signaling molecules on the cell surface is key to their adaptive function. Live imaging of proteins tagged with fluorescent...
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Tethering proteins in membrane traffic
In eukaryotic cells, protein secretion and the transport of materials between membrane-bounded organelles require efficient and accurate delivery of...
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Quantifying the Organization and Dynamics of the Plant Plasma Membrane Across Scales Using Light Microscopy
The plant cell surface continuum is composed of the cell wall, plasma membrane, and cytoskeleton. Plasmodesmata are specialized channels in the cell...
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Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
The oncogene RAS, extensively studied for decades, presents persistent gaps in understanding, hindering the development of effective therapeutic...
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Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments
The binding of the major stress-inducible human 70-kDa heat shock protein (Hsp70) to the anionic phospholipid bis-(monoacylglycero)-phosphate (BMP)...
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Real-time imaging of axonal membrane protein life cycles
The construction of neuronal membranes is a dynamic process involving the biogenesis, vesicular packaging, transport, insertion and recycling of...
