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Studying Dynein Mechanochemistry with an Optical Trap
Molecular motors generate force and mechanical work to perform some of the most energy-demanding cellular processes, such as whole cell motility and...
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Molecular Motors: Subdomain Dynamics and Mechanochemistry
Biological cells contain nano-molecular motors that perform essential functions such as intracellular transport, muscle contraction, and chromosome...
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Green and Bio-Mechanochemical Approach to Silver Nanoparticles Synthesis, Characterization and Antibacterial Potential
The area of nanotechnology has been enjoying enormous research interest recently because of the unique characteristics of nanoscale substances....
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Agronomic Comparison of Mechanochemically Synthesized Zinc Borate and Other Boron Sources Granulated with Macronutrient Fertilizers
PurposeBoron (B) is an essential micronutrient required throughout the growth cycle of plants so effectively supplying crops with B using fertilizers...
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Mechanochemical-assisted extraction and enzymatic hydrolysis of calcium phytate from defatted rice bran
BackgroundMechanochemical-assisted extraction (MCAE) and mechanochemical-assisted enzyme catalysis (MCAEC) methods were developed for extraction and...
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Fast and Easy Transient Mammalian Cell Expression and Purification of Cytoplasmic Dynein
Recombinant protein expression has been key to studying dynein’s mechanochemistry and structure-function relationship. To gain further insight into...
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Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport
The lissencephaly-related protein LIS1 is a critical regulator of cytoplasmic dynein that governs motor function and intracellular localization (for...
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Green Chemistry, Eco-Friendly Chemistry, Biorefinery
Green chemistry aims at reducing the impact of synthesis and transformation processes on the environmental and human health. It is based on twelve...
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Molecular iodine catalyzed C(sp2)–H sulfenylation of biologically active enaminone compounds under mechanochemical conditions and studies on their biocidal activity including molecular docking and DFT
Here we demonstrated a solvent free, mechanochemical I 2 catalyzed C(sp2)–H sulfenylation of enaminones under grinding condition. Only catalytic...
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Circular permutation at azurin’s active site slows down its folding
Circular permutation (CP) is a technique by which the primary sequence of a protein is rearranged to create new termini. The connectivity of the...
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DNA Nanotechnology to Disclose Molecular Events at the Nanoscale and Mesoscale Levels
Self-assembly is commonly seen in living systems and plays a central role in the construction of cellular structures and thus influences the...
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A Mechanocomposite Based on Biogenic Silica and Green Tea Flavonoids Modulates Adaptability of Strawberry Microclones to In Vitro and Ex Vitro Conditions
The purpose was to assess effects of a mechanocomposite (MC) based on biogenic silica and green tea flavonoids in terms of alleviation of the impact...
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Application of nitrogen-rich porous organic polymer for the solid-phase synthesis of 2-amino-4H-benzo[b]pyran scaffolds using ball milling process
AbstractThis paper presents the efficient synthesis of 2-amino-4 H -benzo[ b ]pyrans using mesoporous poly-melamine-formaldehyde as a polymeric...
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A Review on Pharmaceutical Removal from Aquatic Media by Adsorption: Understanding the Influential Parameters and Novel Adsorbents
An increase in pharmaceutical compound consumption around the world has gained considerable attention due to detection and presence of these...
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Kinesin-8 motors: regulation of microtubule dynamics and chromosome movements
Microtubules are essential for intracellular transport, cell motility, spindle assembly, and chromosome segregation during cell division. Microtubule...
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Antibacterial Metal-Organic Frameworks
The continuous evolution of complex resistance mechanisms in pathogens is intimidating the efficacy of current antibiotic therapy in medical and...
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Raman spectroscopy for real-time and in situ monitoring of mechanochemical milling reactions
Solid-state milling has emerged as an alternative, sustainable approach for preparing virtually all classes of compounds and materials. In situ...
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Molecular mechanisms of catch bonds and their implications for platelet hemostasis
Adhesive molecular bonds between blood cells are essential for thrombosis and hemostasis as they provide means for platelet adhesion, aggregation,...
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Lignin Fungal Depolymerization: From Substrate Characterization to Oligomers Valorization
Renewable resources obtained via sustainable methodologies provide an alternative to reduce the dependency on fossil resources. Lignin is the second...