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Evaluation of Molecular Interactions and Cellular Dynamics at the Maternal-Fetal Interface During Placental Morphogenesis
Molecular events at the maternal-fetal interface establish successful pregnancies. Identifying and characterizing the heterogeneous cell population... -
Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis
Maternal antibodies (MAbs) protect against infections in immunologically-immature neonates. Maternally transferred immunity may also be harnessed to...
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Gender Differences in Thyroid Function among Euthyroid Subjects with Positive and Negative Thyroid Antibodies (Antibodies to Thyroid Peroxidase and/or Thyroglobulin)
AbstractThe aim of the study was to demonstrate gender differences in thyroid function among euthyroid subjects, that had negative values of...
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Determination of Maternal and Infant Immune Responses to Pertussis Vaccination in Pregnancy
The Bordetella pertussis bacterium is the causative agent of whoo** cough (pertussis disease). Following recent outbreaks of pertussis,... -
Synergistic Effect of Maternal Micronutrient Supplementation on ORFV DNA Vaccine Immune Response in a Pregnant Model
Contagious ecthyma is a contagious zoonotic disease caused by the Orf virus that can infect farm animals and humans, but no vaccine is available for...
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Periportal hepatocyte proliferation at midgestation governs maternal glucose homeostasis in mice
The maternal liver is challenged by metabolic demands throughout pregnancy. However, hepatocyte dynamics and their physiological significance in...
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Genetic parameters of colostrum and calf serum antibodies in Swedish dairy cattle
BackgroundA sufficient IgG content in the colostrum is essential for the newborn calf, as it provides passive immunity which substantially affects...
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Maternal circadian rhythm disruption affects neonatal inflammation via metabolic reprograming of myeloid cells
Disruption of circadian rhythm during pregnancy produces adverse health outcomes in offspring; however, the role of maternal circadian rhythms in the...
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Disruption of maternal vascular remodeling by a fetal endoretrovirus-derived gene in preeclampsia
BackgroundPreeclampsia, one of the most lethal pregnancy-related diseases, is associated with the disruption of uterine spiral artery remodeling...
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Embryonic signals mediate extracellular vesicle biogenesis and trafficking at the embryo–maternal interface
BackgroundExtracellular vesicles (EVs) are membrane-coated nanoparticles secreted by almost all cell types in living organisms. EVs, as paracrine...
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Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation
BackgroundIntrauterine hematopoietic stem cell transplantation (IUT), potentially curative in congenital haematological disease, is often inhibited...
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Imbalance of Angiogenic and Growth Factors in Placenta in Maternal Hyperhomocysteinemia
AbstractNumerous studies have shown that various adverse factors of different nature and action mechanisms have similar negative influence on...
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Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface
The maternal-fetal interface shares similarities with tumor tissues in terms of the immune microenvironment. Normal pregnancy is maintained due to...
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Maternal aging increases offspring adult body size via transmission of donut-shaped mitochondria
Maternal age at childbearing has continued to increase in recent decades. However, whether and how it influences offspring adult traits are largely...
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Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature
The placenta is a unique organ for ensuring normal embryonic growth in the uterine. Here, we found that maternal RNA transcription in Dlk1-Dio3 ...
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Development and application of a colloidal-gold immunochromatographic strip for detecting Getah virus antibodies
AbstractGetah virus (GETV) is a re-emerging mosquito-borne alphavirus that is highly pathogenic, mainly to pigs and horses. There are no vaccines or...
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Maternal diet disrupts the placenta–brain axis in a sex-specific manner
High maternal weight is associated with detrimental outcomes in offspring, including increased susceptibility to neurological disorders such as...
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The effect of maternal period nutritional status on oro-sensorial fat perception and taste preference in rats
CD36 and GPR120 play an important role in the perception and preference for fat-rich food consumption. We aimed to investigate the relationship...
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Structural basis of the subcortical maternal complex and its implications in reproductive disorders
The subcortical maternal complex (SCMC) plays a crucial role in early embryonic development. Malfunction of SCMC leads to reproductive diseases in...
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Cordycepin delays postovulatory aging of oocytes through inhibition of maternal mRNAs degradation via DCP1A polyadenylation suppression
Postovulatory aging leads to the decline in oocyte quality and subsequent impairment of embryonic development, thereby reducing the success rate of...