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TA-Cloning for Diabetes Treatment: Expressing Corynebacterium Malic Enzyme Gene in E. coli
Diabetes mellitus represents a persistent metabolic condition marked by heightened levels of blood glucose, presenting a considerable worldwide...
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Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Human mitochondrial NAD(P) + -dependent malic enzyme (ME2) is well-known for its role in cell metabolism, which may be involved in cancer or epilepsy....
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Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate
Many types of cancer feature TP53 mutations with oncogenic properties. However, whether the oncogenic activity of mutant p53 is affected by the...
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Overexpression of chloroplastic Zea mays NADP-malic enzyme (ZmNADP-ME) confers tolerance to salt stress in Arabidopsis thaliana
The C4 plants photosynthesize better than C3 plants especially in arid environment. As an attempt to genetically convert C3 plant to C4, the cDNA of...
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Recent advances in the production of malic acid by native fungi and engineered microbes
Malic acid is mainly produced by chemical methods which lead to various environmental sustainability concerns associated with CO 2 emissions and...
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Recent advances in microbial production of L-malic acid
AbstractOver the last few decades, increasing concerns regarding fossil fuel depletion and excessive CO 2 emissions have led to extensive fundamental...
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The combined effect of nitrogen deprivation and overexpression of malic enzyme gene on growth and lipid accumulation in Phaeodactylum tricornutum
Oleaginous microalgae have great application potential in the field of bioenergy. Increasing the biomass and lipid productivity of microalgae is...
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Structural insights into the allosteric site of Arabidopsis NADP-malic enzyme 2: role of the second sphere residues in the regulatory signal transmission
Key messageNADP-ME2 from Arabidopsis thaliana exhibits a distinctive and complex regulation by fumarate, acting as an activator or an inhibitor...
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Prohexadione-calcium improves grape quality by regulating endogenous hormones, sugar and acid metabolism and related enzyme activities in grape berries
Prohexadione-Calcium (Pro-Ca) plays key roles in improving fruit quality and yield by regulating various aspects of plant growth. However, the...
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Carbon dioxide sensitization delays the postharvest ripening and fatty acids composition of Capsicum fruit by regulating ethylene biosynthesis, malic acid and reactive oxygen species metabolism
Present study would be significant in the sustenance of quality characters for postharvest storage of Capsicum fruit with CO 2 -sensitization in...
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Role of C4 photosynthetic enzyme isoforms in C3 plants and their potential applications in improving agronomic traits in crops
As compared to C3, C4 plants have higher photosynthetic rates and better tolerance to high temperature and drought. These traits are highly...
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Valorization of apple and grape wastes with malic acid-degrading yeasts
It is estimated that more than 20% of processed apples and grapes are discarded as waste, which is dominated by pomace rich in malic acid that could...
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Response of organic acid metabolism in the young and ripening grape berries in vitro to ambient temperature
Organic acids, the important flavor compounds in grape berries, are altered by temperature during berry development. To mitigate potential...
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C4 Equivalent Decarboxylation Competence in Tropical Orchids
Tropical xero-epiphytic orchids undergo a photosynthetic mechanism called ‘Crassulacean Acid Metabolism’, a modification of Calvin–Benson cycle. This...
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Classification and Enzyme Properties of Starch Debranching Enzymes
The α-1,6 glycosidic linkages in polysaccharides, including amylose, straight-chain starch, pullulan, and glycogen, are hydrolyzed by starch...
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Identification and engineering a C4-dicarboxylate transporter for improvement of malic acid production in Aspergillus niger
AbstractModification of C 4 -dicarboxylate transport processes is an important strategy for the development of efficient malic acid producing cell...
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Auxin is involved in arbuscular mycorrhizal fungi-promoted tomato growth and NADP-malic enzymes expression in continuous crop** substrates
BackgroundDespite significant limitations of growth medium reuse, a large amount of organic substrate is reused in soilless cultivation of...
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Arbuscular mycorrhizal fungi by inducing watermelon roots secretion phthalates, altering soil enzyme activity and bacterial community composition to alleviate the watermelon wilt
BackgroundLong-term continuous crop** has resulted in the frequent occurrence of fusarium wilt of watermelon ( Citrullus lanatus ). AMF inoculation...
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Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells
Glutamine is a critical metabolite for rapidly proliferating cells as it is used for the synthesis of key metabolites necessary for cell growth and...
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Response of soil physicochemical properties, soil nutrients, enzyme activity and rice yield to rice straw returning in highly saline-alkali paddy soils
This study investigated the effect of rice straw returning on the soil physicochemical properties, nutrients, enzyme activity, and rice yield in...
