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The predictive value of the neutrophil/platelet ratio on in-hospital adverse events and long-term prognosis in patients with coronary artery disease after percutaneous coronary intervention and its possible internal mechanism
The neutrophil-to-platelet ratio (NPR) is considered to be an indicator of inflammatory status. The value of the NPR in predicting in-hospital...
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Differential tempol effects in prostatic cancer: angiogenesis and short- and long-term treatments
Prostate cancer (PCa) is the second cause of cancer death among men worldwide. Several processes are involved in the development and progression of...
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Long-term effects of SARS-CoV-2 infection on human brain and memory
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have caused several waves of outbreaks. From the ancestral strain to...
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Lipoprotein (a) and myocardial infarction: impact on long-term mortality
Background and aimsLipoprotein (a) [Lp(a)] is a genetically regulated lipoprotein particle that is an independent risk factor for coronary...
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Triglyceride to high-density lipoprotein cholesterol ratio associated with long-term adverse clinical outcomes in patients deferred revascularization following fractional flow reserve
BackgroundGuidelines on coronary intermediate lesions strongly recommend deferred revascularization after detecting a normal fractional flow reserve...
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Long-term outcome of cardiac resynchronization therapy patients in the elderly
Heart failure (HF) is a leading cause of mortality and hospitalization in the elderly. However, data are scarce about their response to device...
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Long-term prognosis and educational determinants of brain network decline in older adult individuals
Older adults with lower education are at greater risk for dementia. It is unclear which brain changes lead to these outcomes. Longitudinal...
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Long term outcomes of en-block autotransplantation of a tooth
Repositioning of impacted teeth in the dental arch through en-bloc autotransplantation showed short-term efficacy of 89%. The objective of this study...
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Epithelial-mesenchymal transition-related signaling pathways in gastric Cancer cells distinctively respond to long-term experimental ketosis
BackgroundThe interrelationship between cellular metabolism and the epithelial-to-mesenchymal transition (EMT) process has made it an interesting...
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Long-term prognostic value of left atrial longitudinal strain in an elderly community-based cohort
Despite the well-known importance of left atrial (LA) mechanics in diastolic function, data are scarce regarding the prognostic power of LA...
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Association between the insulin resistance marker TyG index and subsequent adverse long-term cardiovascular events in young and middle-aged US adults based on obesity status
BackgroundA lthough the triglyceride-glucose (TyG) index has been shown to closely correlate with cardiometabolic outcomes and predict cardiovascular...
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Novel targets and their functions in the prognosis of uterine corpus endometrial cancer patients
Aberrant mRNA expression is implicated in uterine corpus endometrial carcinoma (UCEC) oncogenesis and progression. However, effective prognostic...
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Long-term intra- and inter-individual biological variation of serum lipid of HIV-infected and uninfected men participating in the Los Angeles Multi-Center AIDS Cohort Study (MACS)
BackgroundTo assess the long-term biological coefficient of variation within individuals (CV I ) and between individuals (CV G ), effect of aging and...
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Transforming Perspectives in Cardiac Cell Therapy: Hypothesis and Commentary Following Updated Results of a Pilot Study Investigating Very Long-Term Clinical Outcomes in Severe AMI Patients Following Trans-Epicardial Injection of Peripheral Blood CD34+ Cells
Ischemic heart attack is the leading cause of death worldwide. Ten percent of cases will die within an hour. Of the survivors, around 30% will have...
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MicroRNA: Role in Gene Regulation, Disease Prognosis, Radiotherapy, and the Activity of Radioprotectors
AbstractMicroRNAs are small, highly conserved noncoding RNAs (containing about 20 nucleotides), involved in the regulation of gene activity on the...
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Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism
Patients with late-stage and human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) continue to have a very poor...
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Characterizing the key genes of COVID-19 that regulate tumor immune microenvironment and prognosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), a highly heterogeneous malignant tumor associated with a poor prognosis, is a common cause of cancer-related deaths...
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Long-term cancer risk in heterozygous familial hypercholesterolemia relatives: a 25-year cohort study
BackgroundHeterozygous familial hypercholesterolemia (HeFH) due to low-density lipoprotein receptor (LDLR) mutations predisposes patients to highly...
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Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and anti-inflammatory effects in type 2 diabetic rats
BackgroundMesenchymal stem cells (MSCs) exert anti-diabetic effects and improve long-term complications via secretory effects that regulate...
