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Lipid droplets and cellular lipid flux
Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of cells, and sequester lipids to prevent lipotoxicity and...
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Microglia Lipid Droplets in Physiology and Neurodegeneration
Lipid droplets (LDs) are dynamic organelles found in organisms ranging from yeast to humans. Originally thought of as inert lipid-storing structures,...
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Are lipid droplets the picnic basket of brain tumours?
Are lipid droplets (LDs) necessary to maintain the viability of brain tumour cells as they move to new nutrient-poor environments? In turn, could...
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Could Cytoplasmic Lipid Droplets be Linked to Inefficient Oxidative Phosphorylation in Cancer?
Purpose of ReviewTriglyceride-rich cytoplasmic lipid droplets are present in many malignant cancers. It remains controversial as to whether the lipid...
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Extracellular lipidosomes containing lipid droplets and mitochondria are released during melanoma cell division
BackgroundThe incidence of melanoma is increasing worldwide. Since metastatic melanoma is highly aggressive, it is important to decipher all the...
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Visualizing Lipid Droplets in Drosophila Oogenesis
Lipid droplets (LDs) are fat storage organelles highly abundant in oocytes and eggs of many vertebrates and invertebrates. They have roles both...
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SB2301-mediated perturbation of membrane composition in lipid droplets induces lipophagy and lipid droplets ubiquitination
Lipid droplets (LDs) are involved in various biological events in cells along with their primary role as a storage center for neutral lipids....
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Lipid droplets: a cellular organelle vital in cancer cells
Lipid droplets (LDs) are cellular organelles comprising a core of neutral lipids (glycerides, sterols) encased within a single phospholipid membrane,...
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2,5-Dimethoxy-Benzylidene-Rhodanine and Its Acyclic Analogues as Selective Fluorogenic Dyes for Lipid Droplets of Living Cells
AbstractObjective: Lipid droplets (adiposomes) are cellular organelles with distinguish structure and functions that play significant role in energy...
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Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids
Dietary mono-unsaturated fatty acids (MUFAs) are linked to longevity in several species. But the mechanisms by which MUFAs extend lifespan remain...
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HNRNPL Increases WSB1 mRNA Stability to Promote Proliferation and Lipid Droplets in Clear Cell Renal Cell Carcinoma
This study aims to explore the possible effect and mechanism of heterogeneous nuclear ribonucleoprotein L (HNRNPL) on the lipid droplet and...
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In vivo observation of lipid droplets in coral calcifying cells: fat stores to fuel the reef-building process?
The calcifying cells of corals are responsible for skeleton formation, a process that is the basis for reef building. Their cell biology is therefore...
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Cinnamaldehyde affects lipid droplets metabolism after adipogenic differentiation of C2C12 cells
BackgroundBased on our previous research conducted on cinnamaldehyde (CA) exhibiting its ability to improve the growth performance of fattening pigs...
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Beyond energy provider: multifunction of lipid droplets in embryonic development
Since the discovery, lipid droplets (LDs) have been recognized to be sites of cellular energy reserves, providing energy when necessary to sustain...
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Functionalized Lipid Droplets and Microfluidics Approach to Study Immune Cell Polarity In Vitro
The study of lymphocyte polarization upon antigen encounter typically relies on the random pairing between the cells of interest and a stimulating...
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Lipid droplets and perilipins in canine osteosarcoma. Investigations on tumor tissue, 2D and 3D cell culture models
Lipid droplets were identified as important players in biological processes of various tumor types. With emphasis on lipid droplet-coating proteins...
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The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Lipid droplets (LDs) are crucial organelles for energy storage and lipid homeostasis. Autophagy of LDs is an important pathway for their catabolism,...
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Nile Red and BODIPY Staining of Lipid Droplets in Mouse Oocytes and Embryos
Lipid droplets (LDs) are intracellular structures composed of hydrophobic lipids. Their amount in oocytes and embryos varies among the mammalian...
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Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis
Autophagy is an evolutionarily conserved process that aims to maintain the energy homeostasis of the cell by recycling long-lived proteins and...
