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Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO
Liangyi Gao (LYG), a traditional Chinese medicine, is composed of Ginseng and Radix Rehmanniae Preparata, both of which have been shown to have...
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Superresolution live-cell imaging reveals that the localization of TMEM106B to filopodia in oligodendrocytes is compromised by the hypomyelination-related D252N mutation
Hypomyelination leukodystrophies constitute a group of heritable white matter disorders exhibiting defective myelin development. Initially identified...
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Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function
Aging and aging-related disorders contribute to formidable socioeconomic and healthcare challenges. Several promising small molecules have been...
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OPA1 and MICOS Regulate mitochondrial crista dynamics and formation
Mitochondrial cristae are the main site for oxidative phosphorylation, which is critical for cellular energy production. Upon different physiological...
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Gill transcriptomes reveal expression changes of genes related with immune and ion transport under salinity stress in silvery pomfret (Pampus argenteus)
Salinity is a major ecological factor in the marine environment, and extremely important for the survival, development, and growth of fish. In this...
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Light-sheet fluorescence imaging charts the gastrula origin of vascular endothelial cells in early zebrafish embryos
It remains challenging to construct a complete cell lineage map of the origin of vascular endothelial cells in any vertebrate embryo. Here, we report...
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Effects of fasting on the activities and mRNA expression levels of lipoprotein lipase (LPL), hormone-sensitive lipase (HSL) and fatty acid synthetase (FAS) in spotted seabass Lateolabrax maculatus
To investigate the effects of fasting on lipid metabolism in spotted seabass muscle and liver tissues, we analyzed mRNA levels and enzyme activities...
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Resveratrol attenuates high glucose-induced endothelial cell apoptosis via mediation of store-operated calcium entry
The aim of this study was to evaluate the influence of resveratrol on HG-induced calcium entry in islet microvascular (MS-1) endothelial cells. MS-1...
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Molecular cloning and expression patterns of two tumor necrosis factor alpha genes in crucian carp (Carassius carassius)
Tumor necrosis factor (TNF[31]) is a potent inflammatory cytokine produced during inflammation. In this study, two crucian carp TNF -α genes, TNF α-1...
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Seasonal dynamics of gas regulation service in forest ecosystem
Using the 3-year observational data from ChinaFlux (Chinese Terrestrial Ecosystem Flux Research Network), we studied the gas regulation flux dynamics...