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Lac-Phe mediates the effects of metformin on food intake and body weight
Metformin is a widely prescribed anti-diabetic medicine that also reduces body weight. There is ongoing debate about the mechanisms that mediate...
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Defining Membrane Protein Topology Using pho-lac Reporter Fusions
Experimental determination of membrane protein topology can be achieved using various techniques. Here, we present the pho-lac dual reporter system,... -
Unraveling bacterial diversity of the Indian Lac Insect Kerria lacca (Kerr) using next generation sequencing
The Indian lac insect, Kerria lacca (Kerr) is an industrially important insect because of its resin and pigment synthesizing capacity. Lac insects...
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Evaluation of certain plant hosts for the lac insect
Lac, a natural resinous substance having profound economic importance, is a secretion of Lac insect Kerria chinensis (Hemiptera: Kerridae). Lac is...
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Progress in fed-batch culture for recombinant protein production in CHO cells
AbstractNearly 80% of the approved human therapeutic antibodies are produced by Chinese Hamster Ovary (CHO) cells. To achieve better cell growth and...
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Decolorization of Textile Effluent by Trametes hirsuta Bm-2 and lac-T as Possible Main Laccase-Contributing Gene
The decolorization of dye and textile effluent by Trametes hirsuta was studied in both induced and non-induced media. A removal of 70–100% of the...
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Effects of process intensification on homogeneity of an IgG1:κ monoclonal antibody during perfusion culture
AbstractThe pharmaceutical industry employs various strategies to improve cell productivity. These strategies include process intensification,...
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Hydrogen sulfide promoted cell differentiation, antioxidant ability, and flavonoids accumulation in Ginkgo biloba L. suspension cells
Hydrogen sulfide (H 2 S) as the third gasotransmitter could regulate many physiological processes such as growth and stress responses in plants....
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The activation impact of lactobacillus-derived extracellular vesicles on lipopolysaccharide-induced microglial cell
Perioperative neurocognitive dysfunction (PND) emerges as a common postoperative complication among elderly patients. Currently, the mechanism of PND...
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Osteogenic properties and anti-osteoporosis activity of calcium hydroxyapatite from Katsuwonus pelamis bone and its water-soluble forms
In this study, the osteogenic properties and anti-osteoporosis activity of calcium hydroxyapatite (HA) obtained from Katsuwonus pelamis tuna bone and...
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The role of the msaABCR operon in implant-associated chronic osteomyelitis in Staphylococcus aureus USA300 LAC
BackgroundThe msaABCR operon regulates several staphylococcal phenotypes such as biofilm formation, capsule production, protease production,...
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A lipase from Lacticaseibacillus rhamnosus IDCC 3201 with thermostability and pH resistance for use as a detergent additive
AbstractLipases are important biocatalysts and ubiquitous in plants, animals, and microorganisms. The high growth rates of microorganisms with low...
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Ability of marine-derived fungi isolated from polluted saline environment for enzymatic hydrocarbon remediation
Marine-derived fungi have attracted much attention due to their ability to present a new biosynthetic diversity. About 50 fungal isolates were...
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Enhancement of Photo-Fermentative Hydrogen Production with Co-culture of Rhodobacter capsulatus and Rhodospirillum rubrum by Using Medium Renewal Strategy
In recent years, there has been a significant deal of interest in the photo-fermentation-based synthesis of biological hydrogen due to its unique...
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ClearColi as a platform for untagged pneumococcal surface protein A production: cultivation strategy, bioreactor culture, and purification
AbstractSeveral studies have searched for new antigens to produce pneumococcal vaccines that are more effective and could provide broader coverage,...
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Caatinga, Amazon and Atlantic Forest as natural sources for microbial lignocellulolytic enzymes
Brazilian biomes are important sources for environmental microorganisms, including efficient metabolic machineries, like actinomycetes. These...
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Molecular characterization of an Isaria fumosorosea (Wize) native strain, and its pathogenicity on Eublemma amabilis (Lepidoptera: Noctuidae)
BackgroundEublemma amabilis Moore (Lepidoptera: Noctuidae) is an important pest of lac insect, Kerria spp . (Hemiptera: Tachardiidae: Coccoidea)...
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Lactobacillus johnsonii CPN23 vis-à-vis Lactobacillus acidophilus NCDC15 Improves Gut Health, Intestinal Morphometry, and Histology in Weaned Wistar Rats
The present investigation was carried out with the aim to establish the comparative efficacy of a canine-sourced probiotic meant for canine feeding...
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Efficient crop straws biotreatment using the fungus Cerrena Unicolor GC.u01
Lignin is main composition of agricultural biomass which can be decomposed through enzymatic hydrolysis by fungi. However, there are still needs to...
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The Effects of Social Hierarchy Establishment in Resident-Intruder Model on Testicular Function in Laboratory Mice of Different Inbred Strains
AbstractMale reproductive success is known to be related with ability to social dominance and number and quality of spermatozoa as well as the...