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Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution
The dry mass and the orientation of biomolecules can be imaged without a label by measuring their permittivity tensor (PT), which describes how...
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Label-free nanoscale map** of intracellular organelle chemistry
The ability to image cell chemistry at the nanoscale is key for understanding cell biology, but many optical microscopies are restricted by the...
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Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging
Dynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance...
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Label-Free Quantitative Proteomics in Plant
Label-free quantitation (LFQ) proteomics, mainly based on the extraction of the peptide (precursor) intensity at the MS1 (mass spectrum 1) level,...
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EVATOM: an optical, label-free, machine learning assisted embryo health assessment tool
The combination of a good quality embryo and proper maternal health factors promise higher chances of a successful in vitro fertilization (IVF)...
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Label-free morpho-molecular phenoty** of living cancer cells by combined Raman spectroscopy and phase tomography
Accurate, rapid and non-invasive cancer cell phenoty** is a pressing concern across the life sciences, as standard immuno-chemical imaging and...
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Autofluorescence Label-Free Imaging of the Liver Reticular Structure
AutofluorescenceAutofluorescence rising from biological substrates under proper excitation light depends on the presence of specific endogenous...
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Inferences on Landscape Pattern
Landscape ecologists are deeply invested in pattern: how to measure it, how to interpret those measures, and how to use them in applications. Much of...
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msmsEDA & msmsTests: Label-Free Differential Expression by Spectral Counts
msmsTests is an R/Bioconductor package providing functions for statistical tests in label-free LC-MS/MS data by spectral counts. These functions aim...
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Label-free quantitative proteomics in serum reveals candidate biomarkers associated with low bone mineral density in Mexican postmenopausal women
Postmenopausal osteoporosis is a public health problem leading to an increased risk of fractures, negatively impacting women’s health. The absence of...
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High-resolution assessment of multidimensional cellular mechanics using label-free refractive-index traction force microscopy
A critical requirement for studying cell mechanics is three-dimensional assessment of cellular shapes and forces with high spatiotemporal resolution....
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Achieving quantitative reproducibility in label-free multisite DIA experiments through multirun alignment
DIA is a mainstream method for quantitative proteomics, but consistent quantification across multiple LC-MS/MS instruments remains a bottleneck in...
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SRTsim: spatial pattern preserving simulations for spatially resolved transcriptomics
Spatially resolved transcriptomics (SRT)-specific computational methods are often developed, tested, validated, and evaluated in silico using...
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Pattern recognition of topologically associating domains using deep learning
BackgroundRecent increasing evidence indicates that three-dimensional chromosome structure plays an important role in genomic function. Topologically...
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Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer
BackgroundColorectal cancer (CRC) is one of the major causes of cancer-related death worldwide. Although commercial biomarkers of CRC are currently...
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A “pulse-stairstep” longitudinal pattern of larval fish assemblages in a channelized floodplain river downstream of a dam: dominant influences of major tributaries with a “confluence refuge concept”
We investigated larval fish assemblages in the Yangtze River downstream of the Three Gorges Dam to test the influence of tributary inputs on the...
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Multi-resBind: a residual network-based multi-label classifier for in vivo RNA binding prediction and preference visualization
BackgroundProtein-RNA interactions play key roles in many processes regulating gene expression. To understand the underlying binding preference,...
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Study on spoilage potential and its molecular basis of Shewanella putrefaciens in response to cold conditions by Label-free quantitative proteomic analysis
To elucidate how Shewanella putrefaciens survives and produces spoilage products in response to cold conditions, the metabolic and protease activity...
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Effect of Probiotic Supplementation on the Gut Microbiota Composition of Infants Delivered by Cesarean Section: An Exploratory, Randomized, Open-label, Parallel-controlled Trial
BackgroundInfants born via cesarean section (CS) are at an increased risk of immune-related diseases later in life, potentially due to altered gut...
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Prescription pattern analysis of Type 2 Diabetes Mellitus: a cross-sectional study in Isfahan, Iran
BackgroundPatients with Type 2 Diabetes Mellitus (T2DM) are at a higher risk of polypharmacy and more susceptible to irrational prescriptions;...
