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Label-Free Quantitation of Endogenous Peptides
Liquid chromatography–mass spectrometry (LC-MS)-based peptidomics methods allow for the detection and identification of many peptides in a complex... -
Label-free Brillouin endo-microscopy for the quantitative 3D imaging of sub-micrometre biology
This report presents an optical fibre-based endo-microscopic imaging tool that simultaneously measures the topographic profile and 3D viscoelastic...
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Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution
The dry mass and the orientation of biomolecules can be imaged without a label by measuring their permittivity tensor (PT), which describes how...
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TPpred-LE: therapeutic peptide function prediction based on label embedding
BackgroundTherapeutic peptides play an essential role in human physiology, treatment paradigms and bio-pharmacy. Several computational methods have...
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Label-free morpho-molecular phenoty** of living cancer cells by combined Raman spectroscopy and phase tomography
Accurate, rapid and non-invasive cancer cell phenoty** is a pressing concern across the life sciences, as standard immuno-chemical imaging and...
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Label-free nanoscale map** of intracellular organelle chemistry
The ability to image cell chemistry at the nanoscale is key for understanding cell biology, but many optical microscopies are restricted by the...
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Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration
Neurological disorders, including spinal cord injury, peripheral nerve injury, traumatic brain injury, and neurodegenerative diseases, pose...
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Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
BackgroundQuantitative proteomics is an indispensable tool in life science research. However, there is a lack of reference materials for evaluating...
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EVATOM: an optical, label-free, machine learning assisted embryo health assessment tool
The combination of a good quality embryo and proper maternal health factors promise higher chances of a successful in vitro fertilization (IVF)...
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Consumer preference for label presentations of freshness, taste, and serving suggestion on fresh fish packages of Japanese flounder Paralichthys olivaceus
Understanding consumer choice behavior for seafood is important for the efficient and sustainable use of marine resources and the improvement of...
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Autofluorescence Label-Free Imaging of the Liver Reticular Structure
AutofluorescenceAutofluorescence rising from biological substrates under proper excitation light depends on the presence of specific endogenous... -
DNA as Hereditary Material
The relative simplicity of the structure of deoxyribonucleic acid (DNA) and the complexity of inheritance led to the assumption that DNA was not the... -
4D label-free proteomics analysis of oxygen-induced retinopathy with or without anti-VEGF treatment
Oxygen-induced retinopathy (OIR) animal model is widely used for retinopathy of prematurity (ROP) researches. The purpose of this study was to...
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In situ label-free X-ray imaging for visualizing the localization of nanomedicines and subcellular architecture in intact single cells
Understanding the intracellular behaviors of nanomedicines and morphology variation of subcellular architecture impacted by nanomaterial–biology...
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msmsEDA & msmsTests: Label-Free Differential Expression by Spectral Counts
msmsTests is an R/Bioconductor package providing functions for statistical tests in label-free LC-MS/MS data by spectral counts. These functions aim... -
Validation of MS/MS Identifications and Label-Free Quantification Using Proline
In the proteomics field, the production and publication of reliable mass spectrometry (MS)-based label-free quantitative results is a major concern.... -
Transplanted human photoreceptors transfer cytoplasmic material but not to the recipient mouse retina
BackgroundThe discovery of material transfer between transplanted and host mouse photoreceptors has expanded the possibilities for utilizing...
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Material category of visual objects computed from specular image structure
Recognizing materials and their properties visually is vital for successful interactions with our environment, from avoiding slippery floors to...
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Structural characterization of protein-material interfacial interactions using lysine reactivity profiling-mass spectrometry
Understanding how proteins and materials interact is useful for evaluating the safety of biomedical micro/nanomaterials, toxicity estimation and...
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LIVECell—A large-scale dataset for label-free live cell segmentation
Light microscopy combined with well-established protocols of two-dimensional cell culture facilitates high-throughput quantitative imaging to study...