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Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia
This study provides the first comprehensive report on the molecular characteristics of African swine fever virus (ASFV) variants in Serbia between...
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The mitochondrial genome sequence of Syagrus coronata (Mart.) Becc. (Arecaceae) is characterized by gene insertion within intergenic spaces
Syagrus coronata (Mart.) Becc. belongs to the Arecaceae family. It is a species native to Brazil of ecological, social, and economic importance. To...
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Mitochondrial genome of Hancornia speciosa gomes: intergenic regions containing retrotransposons and predicted genes
BackgroundPlant mitochondrial genomes are characterized by high homologous recombination, extensive intergenic spacers, conservation in DNA...
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Transposition Distance Considering Intergenic Regions for Unbalanced Genomes
In seminal works of genome rearrangements, the distance between two genomes is measured by the minimum number of rearrangements (e.g., reversals,...
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Genome Stability of Bacillus velezensis after Two-Year Exposure in Open Space
Abstract —Spore-forming bacteria have a unique resistance to negative environmental conditions, including aggressive space factors, and are an...
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Influence of land use on soil microbial communities of sub Himalayas of India: insights from phospholipid fatty acid profiles, ribosomal intergenic spacer profiles, soil enzymes, and carbon pools
Land use and management practices have a significant impact on soil microbial populations and community composition, thereby influencing ecosystem...
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Intergenic RNA mainly derives from nascent transcripts of known genes
BackgroundEukaryotic genomes undergo pervasive transcription, leading to the production of many types of stable and unstable RNAs. Transcription is...
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Exosome based analysis for Space Associated Neuro-Ocular Syndrome and health risks in space exploration
Molecular profiling to characterize the effects of environmental exposures is important from the human health and performance as well as the...
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Tick species from cattle in the Adama Region of Ethiopia and pathogens detected
Ticks will diminish productivity among farm animals and transmit zoonotic diseases. We conducted a study to identify tick species infesting slaughter...
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CRISPR Interference-Based Functional Small RNA Genomics
Small RNAs (sRNAs) are versatile regulators universally present in species across the prokaryotic kingdom, yet their functional characterization...
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Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans
Epigenetic changes during long-term spaceflight are beginning to be studied by NASA’s twin astronauts and other model organisms. Here, we evaluate...
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In silico analysis of NHP2 membrane protein, a novel vaccine candidate present in the RD7 region of Mycobacterium tuberculosis
Mycobacterium tuberculosis , the etiological agent of tuberculosis, is one of the trickiest pathogens. We have only a few protective shields, like the...
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The Structure, Expression, and Non-Canonical Functions of Human rDNA: The Role of Non-Coding Regions
AbstractThe genes coding for the rRNAs seem evolutionary conserved on the first glance, but astonish one with their variability in the structure and...
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Effect of space flight on the behavior of human retinal pigment epithelial ARPE-19 cells and evaluation of coenzyme Q10 treatment
Astronauts on board the International Space Station (ISS) are exposed to the damaging effects of microgravity and cosmic radiation. One of the most...
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The complete chloroplast genome of rabbiteye blueberry (Vaccinium ashei) and comparison with other Vaccinium species
In order to clarify the characteristics of the chloroplast (cp) genome of Vaccinium ashei Reade cv. ‘brightwell’ and understand its phylogenetic...
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The mitochondrial genome of Faughnia haani (Stomatopoda): novel organization of the control region and phylogenetic position of the superfamily Parasquilloidea
BackgroundStomatopod crustaceans are aggressive marine predators featuring complex compound eyes and powerful raptorial appendages used for...
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Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations
Exposure to environmental mutagens increases the risk of cancer and genetic disorders. We used Duplex Sequencing (DS), a high-accuracy...
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Gene regulation in time and space during X-chromosome inactivation
X-chromosome inactivation (XCI) is the epigenetic mechanism that ensures X-linked dosage compensation between cells of females (XX karyotype) and...
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Recovery of missing single-cell RNA-sequencing data with optimized transcriptomic references
Single-cell RNA-sequencing (scRNA-seq) is an indispensable tool for characterizing cellular diversity and generating hypotheses throughout biology....
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Liquid–liquid phase separation as an organizing principle of intracellular space: overview of the evolution of the cell compartmentalization concept
At the turn of the twenty-first century, fundamental changes took place in the understanding of the structure and function of proteins and then in...
