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Genome-wide epigenetic dynamics during postnatal skeletal muscle growth in Hu sheep
Hypertrophy and fiber transformation are two prominent features of postnatal skeletal muscle development. However, the role of epigenetic...
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Comparative whole-genome resequencing to uncover selection signatures linked to litter size in Hu Sheep and five other breeds
Hu sheep (HS), a breed of sheep carrying the FecB mutation gene, is known for its “year-round estrus and multiple births” and is an ideal model for...
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Investigation of SNP markers for the melatonin production trait in the Hu sheep with bulked segregant analysis
BackgroundAs an important reproductive hormone, melatonin plays an important role in regulating the reproductive activities of sheep and other...
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Nutrient availability of roughages in isocaloric and isonitrogenous diets alters the bacterial networks in the whole gastrointestinal tract of Hu sheep
BackgroundThe nutrient availability of roughages could affect the dietary utilization efficiency of ruminants even in isocaloric and isonitrogenous...
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Effect of liver receptor homolog-1 on cell apoptosis and steroid hormone secretion on granulosa cells from Hu sheep
The apoptosis of granulosa cells can result in follicular atresia, a key process in follicle selection and development. The related molecular...
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Single-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes
BackgroundIn the modern sheep production systems, the reproductive performance of ewes determines the economic profitability of farming. Revealing...
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Transcriptome analysis revealed differences in gene expression in sheep muscle tissue at different developmental stages
BackgroundThe analysis of differentially expressed genes in muscle tissues of sheep at different ages is helpful to analyze the gene expression...
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Identification and analysis of differentially expressed microRNAs in endometrium to explore the regulation of sheep fecundity
BackgroundMicroRNAs (miRNAs) play an important regulatory role in mammalian reproduction. Currently, most studies are primarily concentrated on...
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A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication
The Y chromosome plays key roles in male fertility and reflects the evolutionary history of paternal lineages. Here, we present a de novo genome...
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Whole-genome resequencing of the native sheep provides insights into the microevolution and identifies genes associated with reproduction traits
BackgroundSheep genomes undergo numerous genes losses, gains and mutation that generates genome variability among breeds of the same species after...
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Functional probiotics of lactic acid bacteria from Hu sheep milk
BackgroundProbiotics are being considered as valuable microorganisms related to human health. Hu sheep is referred as one of the important sheep...
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Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails
BackgroundHu sheep and Tibetan sheep in China are characterized by fat tails and thin tails, respectively. Several transcriptomes have been conducted...
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Compilations and updates on residual feed intake in sheep
The increasing global demand for food and the strong effect of climate change have forced animal science to advance regarding new methods of...
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Identification and characterization of circular RNAs in association with the feed efficiency in Hu lambs
BackgroundCircular RNA (circRNA), as a new members of noncoding RNA family, have vital functions in many biological processes by as microRNA sponges...
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Recent advances in the genomic resources for sheep
Sheep ( Ovis aries ) provide a vital source of protein and fibre to human populations. In coming decades, as the pressures associated with rapidly...
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Exploring the rumen microbiota of Hu lambs in response to diet with paper mulberry
AbstractPaper mulberry ( Broussonetia papyrifera ), as a new woody forage with high-protein characteristic, is being widely used in ruminant feeding....
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Portulaca oleracea exhibited anti-coccidian activity, fortified the gut microbiota of Hu lambs
Coccidia of the genus Eimeria are important pathogens that cause coccidiosis in livestock and poultry. Due to the expansion of intensive farming,...
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Key mRNAs and lncRNAs of pituitary that affect the reproduction of FecB + + small tail han sheep
BackgroundThe pituitary directly regulates the reproductive process through follicle-stimulating hormone (FSH) and luteinizing hormone (LH)....
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Dynamic changes of rumen microbiota and serum metabolome revealed increases in meat quality and growth performances of sheep fed bio-fermented rice straw
BackgroundProviding high-quality roughage is crucial for improvement of ruminant production because it is an essential component of their feed. Our...
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Integration of selective sweeps across the sheep genome: understanding the relationship between production and adaptation traits
BackgroundLivestock populations are under constant selective pressure for higher productivity levels for different selective purposes. This pressure...