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Lipid droplets and cellular lipid flux
Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of cells, and sequester lipids to prevent lipotoxicity and...
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Autophagy regulates sex steroid hormone synthesis through lysosomal degradation of lipid droplets in human ovary and testis
Autophagy is an evolutionarily conserved process that aims to maintain the energy homeostasis of the cell by recycling long-lived proteins and...
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Changes in root endogenous hormone levels and rhizosphere fungi diversity in alfalfa under drought stress
To explain the relationship between rhizosphere fungi diversity and community composition of alfalfa under drought stress and endogenous hormones in...
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The role of octopamine and crustacean hyperglycemic hormone (CHH) in branchial acid–base regulation in the European green crab, Carcinus maenas
Crustaceans’ endocrinology is a vastly understudied area of research. The major focus of the studies on this topic to date has been on the molting...
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Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis
An imbalance of human mesenchymal stem cells (hMSCs) adipogenic and osteogenic differentiation is crucial in the pathogenesis of osteoporosis, and...
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Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells
Luteinizing hormone (LH) stimulates the synthesis and secretion of the key steroid hormone estrogen, which subsequently promotes ovarian follicular...
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CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis
BackgroundEndometriosis (EMs) is a common benign gynecological disease that affects approximately 10% of females of reproductive age. Endometriosis...
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Sirt5-mediated desuccinylation of OPTN protects retinal ganglion cells from autophagic flux blockade in diabetic retinopathy
Retinal neurodegeneration develops early in the course of diabetic retinopathy (DR), and our previous research showed that succinate accumulation...
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Effects of magnetic flux density on germination and seedling growth in Oryza sativa var. Glutinosa
The effects of magnetic field intensity on the growth of Niew Khiaw Ngoo ( Oryza sativa var . Glutinosa) tissue culture was studied in order to...
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Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells
BackgroundThyroid hormone triiodothyronine (T3) is essential for embryogenesis and is commonly used during in vitro fertilization to ensure...
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Corticotropin releasing hormone promotes inflammatory bowel disease via inducing intestinal macrophage autophagy
Psychosocial stress is a vital factor contributing to the pathogenesis and progression of inflammatory bowel disease (IBD). The contribution of...
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Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization and autophagic flux inhibition
The autophagy-mediated lysosomal pathway plays an important role in conferring stress tolerance to tumor cells during cellular stress such as...
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Changes in root architecture and endogenous hormone levels in alfalfa under phosphorus stress
To explain changes in plant growth, root architecture, and endogenous hormones of different root-type alfalfa to phosphorus (P) stress (non-stressed...
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A low body-color regulating ability of spotted halibut Verasper variegatus: Evaluation of the roles of melanin-concentrating hormone and proopiomelanocortin systems
In teleosts, melanin-concentrating hormone (MCH) induces body brightening. On the other hand, α-melanophore-stimulating hormone (α-MSH), derived from...
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GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia
Severe cases of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are associated with elevated blood glucose levels and...
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Plant hormone crosstalk mediated by humic acids
BackgroundThe reliance on chemical inputs to support high yields is the Achilles’ heel of modern crop production. The soil organic matter management...
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Development of suspension culture technology and hormone effects on anthocyanin biosynthesis for red Cyclocarya paliurus cells
AbstractPlant cell culture is a good way to produce anthocyanins owing to its outstanding advantages of short cycles and no limitation on natural...
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Quantitative flux analysis in mammals
Altered metabolic activity contributes to the pathogenesis of a number of diseases, including diabetes, heart failure, cancer, fibrosis and...
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Humic acid overcomes salinity barriers and stimulates growth of Urochondra setulosa by altering ion-flux and photochemistry
Humic acid (HA) is a known bio-stimulator, but its role in salinity tolerance is not well reported. This study examined the effect of HA (0, 250 and...
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Major vacuolar TPC1 channel in stress signaling: what matters, K+, Ca2+ conductance or an ion-flux independent mechanism?
Two-pore cation channel, TPC1, is ubiquitous in the vacuolar membrane of terrestrial plants and mediates the long distance signaling upon biotic and...
