Search
Search Results
-
The modification of nisin with homocysteine thiolactone and its effect on antimicrobial activity
The aim of the present study is to make an important contribution to the literature by focusing on the preparation of the N-homocysteine conjugate of...
-
Homocysteine-Thiolactone Modulates Gating of Mitochondrial Voltage-Dependent Anion Channel (VDAC) and Protects It from Induced Oxidative Stress
AbstractThe gating of the Voltage-Dependent Anion Channel (VDAC) is linked to oxidative stress through increased generation of mitochondrial ROS with...
-
To Study the Role of Serum Homocysteine Levels and Ocular Involvement in Retinal Vasculitis
Idiopathic retinal vasculitis is a chronic disease of unknown aetiology which results in ocular morbidity in patients of productive age group....
-
Investigating metabolic dysregulation in serum of triple transgenic Alzheimer’s disease male mice: implications for pathogenesis and potential biomarkers
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease that lacks convenient and accessible peripheral blood diagnostic markers and...
-
Comparative Assessment of the Functional Activity of Rat Epididymal Mitochondria in Oxidative Stress Induced by Hyperhomocysteinemia and L-NAME Administration
AbstractThe state of protein carbonylation with the determination of the adaptive reserve potential and analysis of the proportion of primary and...
-
Autoantibody Recognition of Natural and Homocysteinylated Alpha-1 Antitrypsin: Indirect Enzyme-Linked Immunosorbent Assay (ELISA) Quantification in Sera
In this chapter, indirect enzyme-linked immunosorbent assays (ELISAs) to quantitatively measure autoantibodies directed to human natural and...
-
Folic acid alleviates jaundice of phenylhydrazine (PHA)-induced neonatal rats by reducing Lys-homocysteinylation of albumin
Neonatal jaundice is a common symptom that occurs in neonates during the first month of their life and is generally divided into physiological and...
-
Deciphering agr quorum sensing in Staphylococcus aureus: insights and therapeutic prospects
The emergence of superbugs like methicillin-resistant Staphylococcus aureus exposed the limitations of treating microbial infections using...
-
Quorum Quenching Bacteria as Probiotics
Bacteria regulate their own gene expressionGene expression by producing, releasing and sensing chemical signals from the environment through a...
-
It is the time for quorum sensing inhibition as alternative strategy of antimicrobial therapy
Multiple drug resistance poses a significant threat to public health worldwide, with a substantial increase in morbidity and mortality rates....
-
Erythropoietin: Functions and Therapeutic Potential
AbstractErythropoietin (EPO) exerts its effect on erythroid cells through interaction with the EPO receptor (EPOR), the so-called “canonical...
-
Prenatal Stress in Maternal Hyperhomocysteinemia: Impairments in the Fetal Nervous System Development and Placental Function
AbstractThe article presents current views on maternal hyperhomocysteinemia (HHcy) as an important factor causing prenatal stress and impaired...
-
Proteome profiling, biochemical and histological analysis of diclofenac-induced liver toxicity in Yersinia enterocolitica and Lactobacillus fermentum fed rat model: a comparative analysis
Diclofenac is a hepatotoxic non-steroidal anti-inflammatory drug (NSAID) that affects liver histology and its protein expression levels. Here, we...
-
Trace Element Concentration in the Blood and Aqueous Humor of Subjects with Eye Cataract
Cataract, characterized by the opacification of the lens, is the leading cause of reversible blindness and visual impairment globally. The study aims...
-
The unfolded protein response unfolds
As a key organelle of protein targeting and secretion, the endoplasmic reticulum (ER) plays host to a wide variety of protein maturation steps...
-
Radiopharmaceuticals for Non-Glucose-Specific Oncology (PET and SPECT) (A Review)
AbstractTo date, the most common drug for diagnosis of cancer tumors is [ 18 F]-fluorodeoxyglucose, a radiopharmaceutical for positron emission...
-
A clash of quorum sensing vs quorum sensing inhibitors: an overview and risk of resistance
Indiscriminate use of antibiotics to treat microbial pathogens has caused emergence of multiple drug resistant strains. Most infectious diseases are...
-
Spontaneous Release of Human Serum Albumin S-Bound Homocysteine in a Thiol-Free Physiological Medium
Elevated plasma homocysteine (Hcy) concentrations independently predict cardiovascular disease. However, the transport of Hcy into pathological...
