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1. Autophagy in hepatic ischemia–reperfusion injury

   Hepatic ischemia–reperfusion injury (HIRI) is a major complication of liver resection or liver transplantation that can seriously affect patient’s...

   Benliang Mao, Wei Yuan, ... Bailin Wang in Cell Death Discovery

   Article Open access 05 April 2023
   

2. The Beneficial Influence of Testosterone in Hepatic Ischemia/Reperfusion Injury and Its Possible Mechanisms

   Abstract

   Most studies have indicated that the sex hormone estrogen is hepatoprotective, but little attention has been paid to investigating the effect...

   Y. M. Khaled, M. H. ElSayed, ... M. A. Ahmed in Journal of Evolutionary Biochemistry and Physiology

   Article 01 July 2023
   

3. KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy

   Hepatic ischemia-reperfusion (I/R) injury, a common clinical complication of liver transplantation, gravely affects patient prognosis. Krüppel-like...

   Jiye Li, Dongsheng Yu, ... Shuijun Zhang in Cell Death & Disease

   Article Open access 01 July 2023
   

4. Gp78 deficiency in hepatocytes alleviates hepatic ischemia-reperfusion injury via suppressing ACSL4-mediated ferroptosis

   Ferroptosis, which is driven by iron-dependent lipid peroxidation, plays an essential role in liver ischemia-reperfusion injury (IRI) during liver...

   Changbiao Li, Yichao Wu, ... **ao Xu in Cell Death & Disease

   Article Open access 08 December 2023
   

5. The protective effects of phosphoserine aminotransferase 1 (PSAT1) against hepatic ischemia–reperfusion injury

   Hepatic ischemia–reperfusion (I/R) injury is a severe clinical syndrome, causing a profound medical and socioeconomic burden worldwide. This study...

   Yinzhi Deng, Hesheng Luo in Journal of Cell Communication and Signaling

   Article 06 February 2023
   

6. Spatial transcriptomics analysis of zone-dependent hepatic ischemia-reperfusion injury murine model

   Hepatic ischemia-reperfusion (I/R) injury is a common complication in liver transplantation. The connection between I/R-induced injury response and...

   Jiaqi **n, Ting Yang, ... Wei Gao in Communications Biology

   Article Open access 18 February 2023
   

7. Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis

   Ischemia/reperfusion (I/R)-induced liver injury with severe cell death is a major complication of liver transplantation. Transmembrane member 16A...

   Jiawei Guo, Zihao Song, ... Sijia Liang in Cell Death & Disease

   Article Open access 26 December 2022
   

8. PGC-1α inhibits M2 macrophage polarization and alleviates liver fibrosis following hepatic ischemia reperfusion injury

   Oxidative stress can induce inflammation, promoting macrophage polarization and liver fibrosis following hepatic ischemia-reperfusion (I/R)....

   Yanting Zhang, Linzhong Zhang, ... **uying Zhang in Cell Death Discovery

   Article Open access 07 September 2023
   

9. FOXO1 regulates Th17 cell-mediated hepatocellular carcinoma recurrence after hepatic ischemia-reperfusion injury

   Background

   Hepatic ischemia-reperfusion injury (IRI) is considered as an effecting factor for hepatocellular carcinoma (HCC) recurrence. Th17/Treg...

   Haozhen Ren, Yuyan Chen, ... **glin Wang in Cell Death & Disease

   Article Open access 17 June 2023
   

10. Silencing lncRNA KCNQ1OT1 reduced hepatic ischemia reperfusion injury-induced pyroptosis by regulating miR-142a-3p/HMGB1 axis

    Background

    Based on pre-existing evidence, KCNQ1OT1 has been pointed out to be closely related to myocardial and cerebral ischemia reperfusion injury...

    Canxin Liang, Yanhua Peng, ... Shuangfa Zou in Molecular and Cellular Biochemistry

    Article 29 October 2022
    

11. In vivo Combined Vitamin-D and Bone Marrow Mesenchymal Stem Cell (BM-MSCs) Pretreatment Mitigates Hepatic Ischemia-Reperfusion Induced Hepatocellular Damage in Rats

    Abstract

    Hepatic ischemia-reperfusion (IR) injury is inevitable during liver surgery, causing morbidity and mortality. Recently, a wide range of...

    Gehane M. Hamed, Radwa Hassan Ali, ... Doaa Ahmed Abou-Bakr in Journal of Evolutionary Biochemistry and Physiology

    Article 01 May 2023
    

12. Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling

    Background

    This study seeks to investigate the impacts of Lactobacillus reuteri ( L. reuteri ) on hepatic ischemia-reperfusion (I/R) injury and uncover...

    Leiyi Zhang, **aoxiang Gong, ... **ao**g Li in Biology Direct

    Article Open access 18 March 2024
    

13. Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model

    Background

    Baicalein is the main active flavonoid in Scutellariae Radix and is included in shosaikoto, a Kampo formula used for treating hepatitis and...

    Tetsuya Okuyama, Richi Nakatake, ... Mitsugu Sekimoto in Molecular Biology Reports

    Article 10 May 2024
    

14. MicroRNA-141-3p attenuates oxidative stress-induced hepatic ischemia reperfusion injury via Keap1/Nrf2 pathway

    Background

    Hepatic ischemia reperfusion injury (IRI) is a major factor affecting the prognosis of liver transplantation through a series of severe...

    Tingting Li, Qingsong Chen, ... Zhongjun Wu in Molecular Biology Reports

    Article 29 May 2022
    

15. Ferroptosis in organ ischemia–reperfusion injuries: recent advancements and strategies

    Ferroptosis is a newly discovered type of regulated cell death participated in multiple diseases. Different from other classical cell death programs...

    **aoyu Luan, Peng Chen, ... Guohu Di in Molecular and Cellular Biochemistry

    Article 31 March 2024
    

16. Cellular and molecular mechanisms of cell damage and cell death in ischemia–reperfusion injury in organ transplantation

    Ischemia–reperfusion injury (IRI) is a critical pathological condition in which cell death plays a major contributory role, and negatively impacts...

    George J. Dugbartey in Molecular Biology Reports

    Article 29 March 2024
    

17. Protective Effects of Boric Acid Taken in Different Ways on Experimental Ovarian İschemia and Reperfusion

    Ovarian ischemia is a gynecological emergency that occurs as a result of ovarian torsion, affects women of reproductive age, and reduces ovarian...

    Enes Karaman, Gozde Ozge Onder, ... Arzu Yay in Biological Trace Element Research

    Article 25 September 2023
    

18. Intravenous immunoglobulin is effective in alleviating hepatic ischemia–reperfusion injury: a rat model study

    Background

    Hepatic ischemia–reperfusion injury (I/R) is an important factor affecting the prognosis of patients undergoing liver surgery. This study...

    Zeming Chen, Runzhui Lin, ... **ngmu Liu in Molecular Biology Reports

    Article 02 November 2021
    

19. The forkhead box O3 (FOXO3): a key player in the regulation of ischemia and reperfusion injury

    Forkhead box O3 is a protein encoded by the FOXO3 gene expressed throughout the body. FOXO3 could play a crucial role in longevity and many other...

    Moussa Omorou, Yiwei Huang, ... Hui Xu in Cellular and Molecular Life Sciences

    Article 20 March 2023
    

20. Cellular senescence in ischemia/reperfusion injury

    Ischemia/reperfusion (IR) injury, a main reason of mortality and morbidity worldwide, occurs in many organs and tissues. As a result of IR injury,...

    Chao** Chen, Muxu Zheng, ... Ziqing Hei in Cell Death Discovery

    Article Open access 18 October 2022