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The immunotoxicity of ten insecticides against insect hemocyte cells in vitro
Hemocytes in the hemolymph of insects perform innate immunity, but systematic studies to compare immunotoxicity of pesticides on hemocytes are still...
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Hemophagocytic lymphohistiocytosis diagnosed by bone marrow trephine biopsy in living post-COVID-19 patients: case report and mini-review
Hemophagocytic lymphohistiocytosis (HLH) constitutes a life-threatening inflammatory syndrome. Postmortem histological findings of bone marrow (BM)...
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A Retrospective Study of Clinical and Immunological Features of a Pediatric Population with Talaromyces marneffei Infection
BackgroundTalaromyces marneffei ( T. Marneffei ) infection is considered as an indicator of immunosuppression in immunocompromised individuals,...
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A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease
Age and inflammation are powerful drivers of cardiovascular disease. With the growing recognition that traditional cardiovascular risk factors are...
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Diagnostic and Therapeutic Approach to Multisystem Inflammatory Syndrome and Similar Condition
Abstract —Multisystem inflammatory syndrome in children (MIS-C) can occur in kids, who have severe acute respiratory syndrome coronavirus type 2...
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Immune Response Against Piscine orthoreovirus (PRV) in Salmonids
Piscine orthoreovirus (PRV) infection is extremely common in farmed salmonids. Three genotypes of PRV can infect and cause disease in different...
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Dietary nucleotide supplementation enhances the growth, immune response, and disease resistance of the juvenile giant freshwater prawn, Macrobrachium rosenbergii
A 56-day feeding trial was conducted to study the effects of dietary nucleotides on growth performance, non-specific immunity, and disease resistance...
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Associations between epidemiological and laboratory parameters and disease severity in hospitalized patients with COVID-19 during first and second epidemic waves in middle south Mato Grosso
BackgroundCOVID-19 is a multisystemic disease characterized by respiratory distress. Disease severity is associated with several factors. Here we...
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Interaction between macrophages and ferroptosis
AbstractFerroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid peroxidation and GSH depletion mediated by iron...
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The Possible Role of Selected Vitamins and Minerals in the Therapeutic Outcomes of Leishmaniasis
Leishmaniasis is a protozoal disease declared as an endemic in areas suffering from severe malnutrition and poverty. The factors associated with...
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Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK)...
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CBU Posttransplant Chimerism Analysis Using ChimerMarker™
In the last decade, short tandem repeat (STR) analysis of the posttransplant umbilical cord blood unit (CBU) chimerism has become a remarkable and...
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Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19
SARS-CoV-2, although not being a circulatory virus, spread from the respiratory tract resulting in multiorgan failures and thrombotic complications,...
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Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis
Platelets have emerged as key inflammatory cells implicated in the pathology of sepsis, but their contributions to rapid clinical deterioration and...
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Effects of astragalus polysaccharides on hemocytes phagocytosis and gene expression of immune-related factors in Eriocheir sinensis
The 4-week feeding experiments were conducted to investigate the effects of astragalus polysaccharides (APS) on hemocytes phagocytosis and gene...
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A review of the pleiotropic actions of the IFN-inducible CXC chemokine receptor 3 ligands in the synovial microenvironment
Chemokines are pivotal players in instigation and perpetuation of synovitis through leukocytes egress from the blood circulation into the inflamed...
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HLA-mismatched GPBSC infusion therapy in refractory Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis: an observational study from a single center
BackgroundHemophagocytic lymphohistiocytosis (HLH) is a severe or even fatal inflammatory state. Epstein–Barr virus (EBV) infection-associated HLH...
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SARS-CoV, MERS-CoV, and 2019-nCoV viruses: an overview of origin, evolution, and genetic variations
Coronaviruses are single stranded RNA viruses usually present in bats (reservoir hosts), and are generally lethal, highly transmissible, and...
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CBU Posttransplant Chimerism Analysis Using ChimerMarker™
In the last decade, short tandem repeat (STR) analysis of the posttransplant umbilical cord blood unit (CBU) chimerism has become a remarkable and...