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Bacterial toxins and heart function: heat-labile Escherichia coli enterotoxin B promotes changes in cardiac function with possible relevance for sudden cardiac death
Bacterial toxins can cause cardiomyopathy, though it is not its most common cause. Some bacterial toxins can form pores in the membrane of...
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An Outbreak of Bacillus cereus Emetic Toxin Mediated Food Poisoning After Consumption of Fried Rice in Assam
Bacillus cereus is an emerging food-borne pathogen responsible for two types of food poisoning: emetic and diarrhoeal type. Here we report an emetic...
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Genomic characterization of Staphylococcus aureus from Canastra Minas Artisanal Cheeses
Canastra Minas Artisanal Cheese is produced in the Brazilian State of Minas Gerais using raw milk, rennet, and **o, a natural endogenous starter...
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Genetic transformation and expression of hemagglutinin gene from avian influenza virus in carrot (Daucus carota)
Avian influenza is a disease of poultry that causes economic losses to poultry farms. Conventional vaccine production requires chicken embryos for...
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Pig vaccination strategies based on enterotoxigenic Escherichia coli toxins
Enterotoxigenic Escherichia coli (ETEC) are responsible for diarrhea in humans as well as in farm animals. ETEC infections in newborn, suckling, and...
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Virulence potential of Aeromonas hydrophila isolated from apparently healthy freshwater food fish
Aeromonas hydrophila is considered an important pathogen of fish causing substantial economic loss in aquaculture worldwide. The objective of the...
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Efficacy of heat-labile enterotoxin B subunit-adjuvanted parenteral porcine epidemic diarrhea virus trimeric spike subunit vaccine in piglets
Devastating outbreaks of porcine epidemic diarrhea (PED) started in China in late 2010 and rapidly spread to North America and Asia causing severe...
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Exploring Aeromonas dhakensis in Aldabra giant tortoises: a debut report and genetic characterization
Aeromonas dhakensis (A. dhakensis) is becoming an emerging pathogen worldwide, with an increasingly significant role in animals and human health. It...
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Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance
BackgroundBacillus cereus is implicated in severe foodborne infection in humans. This study intended to assess the occurrence, gro EL gene...
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Cholera toxin: mechanisms of entry into host cells
Cholera toxin moves from the plasma membrane to the ER of host cells to cause disease. Trafficking in this pathway depends on toxin binding to... -
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Spatial and temporal modulation of enterotoxigenic E. coli H10407 pathogenesis and interplay with microbiota in human gut models
BackgroundEnterotoxigenic Escherichia coli (ETEC) substantially contributes to the burden of diarrheal illnesses in develo** countries. With the...
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De Novo Designing a Novel Signal Peptide for Secretion of Neurturin to the Periplasmic Space of Escherichia coli
AbstractNeurotrophic factors, including neurturin, increase the life span of the neurons and prevent neuronal destruction. As recombinant expression...
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Molecular mechanism of Escherichia coli H10407 induced diarrhoea and its control through immunomodulatory action of bioactives from Simarouba amara (Aubl.)
Enterotoxigenic Escherichia coli (ETEC) infection is a major cause of death in children under the age of five in develo** countries. ETEC...
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Genomic virulence features of Beauveria bassiana as a biocontrol agent for the mountain pine beetle population
BackgroundThe mountain pine beetle, Dendroctonus ponderosae , is an irruptive bark beetle that causes extensive mortality to many pine species within...
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Protein-Protein Interactions in Host–Pathogen Interactions
Human body is vulnerable to infection by several causative agents like viruses, bacteria, fungi, and protozoa. Currently, a lot of importance has... -
Chitosan-LeoA-DNA Nanoparticles Promoted the Efficacy of Novel LeoA-DNA Vaccination on Mice Against Helicobacter pylori
More than half of the world’s population is infected with Helicobacter pylori ( H. pylori ), which may lead to chronic gastritis, peptic ulcers, and...
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Plant Molecular Farming for Vaccine Development
Vaccines are effective tools for the prophylaxis of infectious diseases. Various diseases have been eradicated using vaccines, and the importance of... -
Prevalence, Toxin Genes, and Antibiotic Resistance Profiles of Bacillus cereus Isolates from Spices in Antalya and Isparta Provinces in Türkiye
Bacillus cereus is a pathogenic bacterium commonly found in nature and can produce toxins that cause food poisoning. This study aimed to detect the...
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Characterization of virulence determinants and phylogenetic background of multiple and extensively drug resistant Escherichia coli isolated from different clinical sources in Egypt
AbstractEscherichia coli is a multifaceted microbe since some are commensals, normally inhabiting the gut of both humans and animals while others...