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The Grueneberg ganglion controls odor-driven food choices in mice under threat
The ability to efficiently search for food is fundamental for animal survival. Olfactory messages are used to find food while being aware of the...
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Smelling the Basis of Social Connectedness: Chemosensory Communication in Humans
Humans have highly developed social and olfactory competencies. It is the aim of this review to summarize the empirical evidence and theoretical... -
Alarm pheromone and kairomone detection via bitter taste receptors in the mouse Grueneberg ganglion
BackgroundThe mouse Grueneberg ganglion (GG) is an olfactory subsystem specialized in the detection of volatile heterocyclic compounds signalling...
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Avian Chemical Signatures: An Overview
Intraspecific communication in birds can involve the visual, auditory, tactile, and olfactory senses. Although the latter is one of the least studied... -
Drosophila olfaction as a model system for studying human neurological disorders
The fruit fly, Drosophila melanogaster , has been one of the finest systems for decoding myriad puzzles across different domains of biology. Beyond...
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Age-dependent appearance of SARS-CoV-2 entry sites in mouse chemosensory systems reflects COVID-19 anosmia-ageusia symptoms
COVID-19 pandemic has given rise to a collective scientific effort to study its viral causing agent SARS-CoV-2. Research is focusing in particular on...
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The Anatomy and Physiology of Laboratory Mouse
Among the different types of vertebrate and invertebrate animals used in biomedical research, the laboratory mouse is the widely used vertebrate... -
A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers
BackgroundIn most mammals, a vast array of genes coding for chemosensory receptors mediates olfaction. Odorant receptor (OR) genes generally...
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Neural mechanisms of alarm pheromone signaling
Alarm pheromones are important semiochemicals used by many animal species to alert conspecifics or other related species of impending danger. In this...
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The genomic basis of vomeronasal-mediated behaviour
The vomeronasal organ (VNO) is a chemosensory subsystem found in the nose of most mammals. It is principally tasked with detecting pheromones and...
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Testing Smell When It Is Really Vital: Behavioral Assays of Social Odors in the Neonatal Mouse
The initial interactions of mouse newborns with their mother are crucial for their survival. These interactions rapidly end in the pups reaching... -
The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory...
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Genetics of canine olfaction and receptor diversity
Olfaction is a particularly important sense in the dog. Humans selected for this capacity during the domestication process, and selection has...
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The cyclic nucleotide-gated ion channel CNGA3 contributes to coolness-induced responses of Grueneberg ganglion neurons
Localized to the vestibule of the nasal cavity, neurons of the Grueneberg ganglion (GG) respond to cool ambient temperatures. The molecular...
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Receptor guanylyl cyclases in mammalian olfactory function
The contributions of guanylyl cyclases to sensory signaling in the olfactory system have been unclear. Recently, studies of a specialized...
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Immunohistochemical detection of olfactory marker protein in tissues with ectopic expression of olfactory receptor genes
Olfactory marker protein (OMP) is a unique marker of mature olfactory neurons, which specifically express olfactory receptor genes. Widespread...
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Odorant-linked ROS-GC subfamily membrane guanylate cyclase transduction system
This review focuses on the principles of the Ca 2+ -modulated ROS-GC subfamily transduction system linked with the mammalian olfactory transduction...
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Mammalian olfactory receptors: pharmacology, G protein coupling and desensitization
The vertebrate olfactory system recognizes and discriminates between thousands of structurally diverse odorants. Detection of odorants in mammals is...
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Cyclic Nucleotide-Gated Channels
Cyclic nucleotide-gated (CNG) channels are ion channels which are activated by the binding of cGMP or cAMP. The channels are important cellular... -
Neural Computations with Mammalian Infochemicals
The mammalian olfactory system is the most sensitive and discriminating molecular recognition system known, able to detect a few dozen critical...