Search
Search Results
-
GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
G protein-coupled receptor 56 (GPR56/ADGRG1) is a multifunctional adhesion GPCR involved in diverse biological processes ranging from development to...
-
A pathway map of signaling events triggered upon SARS-CoV infection
Severe acute respiratory syndrome coronaviruses (SARS-CoVs) caused worldwide epidemics over the past few decades. Extensive studies on various...
-
A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses
BackgroundPandemics, even more than other medical problems, require swift integration of knowledge. When caused by a new virus, understanding the...
-
Fixation of CO2 by soil fungi: contribution to organic carbon pool and destination of fixed carbon products
Dark microbial CO 2 fixation plays a crucial role in soil organic carbon (SOC) sequestration, but the fungus contributions to this process in varying...
-
The global integrative network: integration of signaling and metabolic pathways
The crosstalk between signaling and metabolic pathways has been known to play key roles in human diseases and plant biological processes. The...
-
SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19
Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has been declared a pandemic by...
-
A modular map of Bradykinin-mediated inflammatory signaling network
Bradykinin, a member of the kallikrein-kinin system (KKS), is associated with an inflammatory response pathway with diverse vascular permeability...
-
Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells
Analysis of the transcriptomic alterations upon chemical challenge, provides in depth mechanistic information on the compound’s toxic mode of action,...
-
Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis
Vascular Endothelial Growth Factor-A (VEGFA) signaling is crucial to the cellular processes involved in angiogenesis. Previously, we assembled a...
-
Role and Applications of Bioinformatics in Improvement of Nutritional Quality and Yield of Crops
Bioinformatics has the major role to play in decoding of the genomes of plants and animals. Bioinformatics is making progress in each and every field...
-
Comprehensive network map of interferon gamma signaling
Interferon gamma (IFN-γ), is a cytokine, which is an important regulator of host defense system by mediating both innate and adaptive immune...
-
A network map of thrombopoietin signaling
Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a cytokine involved in the production of platelets. THPO...
-
Data-driven unsupervised clustering of online learner behaviour
The widespread adoption of online courses opens opportunities for analysing learner behaviour and optimising web-based learning adapted to observed...
-
Bacterial endosymbiont Cardinium cSfur genome sequence provides insights for understanding the symbiotic relationship in Sogatella furcifera host
BackgroundSogatella furcifera is a migratory pest that damages rice plants and causes severe economic losses. Due to its ability to annually migrate...
-
Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast
In the unicellular eukaryote Saccharomyces cerevisiae , Cln3–cyclin-dependent kinase activity enables Start, the irreversible commitment to the cell...
-
Fueled by methane: deep-sea sponges from asphalt seeps gain their nutrition from methane-oxidizing symbionts
Sponges host a remarkable diversity of microbial symbionts, however, the benefit their microbes provide is rarely understood. Here, we describe two...
-
A comparative transcriptome analysis of the novel obligate methanotroph Methylomonas sp. DH-1 reveals key differences in transcriptional responses in C1 and secondary metabolite pathways during growth on methane and methanol
BackgroundMethanotrophs play an important role in biotechnological applications, with their ability to utilize single carbon (C1) feedstock such as...
-
A network map of IL-33 signaling pathway
Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central role in the regulation of immune responses. Its release from...
-
VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis
Vascular endothelial growth factor-A (VEGF-A) is essential for endothelial cell functions associated with angiogenesis. Signal transduction networks...
-
Prophages and adaptation of Staphylococcus aureus ST398 to the human clinic
BackgroundIt has been suggested that prophages in the ST398 S. aureus clone are responsible for expanding ST398's spectrum of action and increasing...
