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Inhibition of WNT/β-catenin signalling during sex-specific gonadal differentiation is essential for normal human fetal testis development
Sex-specific gonadal differentiation is directed by complex signalling promoting development in either male or female direction, while simultaneously...
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Effects of temperature on broodstock conditions, gonadal development and survival of tetraploid and diploid oysters of ‘Haida No. 3’ line (Crassostrea gigas)
Tetraploid oysters are valuable germplasm resources for the production of triploid oysters. However, the broodstock condition and gonadal development...
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Morphology, Histology, and Transcriptome Analysis of Gonadal Development in Octopus minor (Sasaki, 1920)
Octopus minor is an economically important species, but little is known about the histological pattern and regulatory mechanisms during gonadal...
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Effects of exogenous steroid hormones on growth, body color, and gonadal development in the Opsariichthys bidens
To investigate the effects of exogenous steroid hormones on growth, body color, and gonadal development in the Opsariichthys bidens ( O. bidens ),...
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The single-cell chromatin landscape in gonadal cell lineage specification
Gonad development includes sex determination and divergent maturation of the testes and ovaries. Recent advances in measuring gene expression in...
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Characterization of the transcription factor Sox3 regulating the gonadal development of pearlscale angelfish (Centropyge vrolikii)
As a member of the Sox gene family, Sox3 plays a vital role in gonadal development and gametogenesis. Nevertheless, the exact expression pattern of...
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Characterization of Early Gonadal Differentiation and Induction of Sex Reversal in the Rock Bream Oplegnathus fasciatus
Rock bream ( Oplegnathus fasciatus ) is a typical fish that has a unique multiple sex chromosome system (♀X 1 X 1 X 2 X 2 /♂X 1 X 2 Y). We examined the early...
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Comparative transcriptomic analysis of gonadal development and renewal in the ovoviviparous black rockfish (Sebastes schlegelii)
BackgroundThe black rockfish ( Sebastes schlegelii ) has an ovoviviparous reproductive pattern and long-term sperm storage, resulting in asynchronous...
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The effect of thyroxine (T4) and goitrogen on growth, liver, thyroid, and gonadal development of red tilapia (O. mossambicus × O. urolepis hornorum)
This study provides comprehensive results on the growth, thyroid, liver, and gonadal condition, maturity, and sex ratio in red tilapia exposed to...
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Characterization of the Nanog gene involved in the gonadal development in pearlscale angelfish (Centropyge vrolikii)
The homeodomain transcription factor Nanog plays a crucial role in the embryonic and gonadal development and the maintenance of embryonic stem cells...
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The m6A methylation regulates gonadal sex differentiation in chicken embryo
BackgroundAs a ubiquitous reversible epigenetic RNA modification, N6-methyladenosine (m6A) plays crucial regulatory roles in multiple biological...
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Loss of NEDD4 causes complete XY gonadal sex reversal in mice
Gonadogenesis is the process wherein two morphologically distinct organs, the testis and the ovary, arise from a common precursor. In mammals,...
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Analyzing the gonadal transcriptome of the frog Hoplobatrachus rugulosus to identify genes involved in sex development
BackgroundThe tiger frog ( Hoplobatrachus rugulosus ) is listed as a national Class II protected species in China. In the context of global warming,...
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Gonadal sex patterns p21-induced cellular senescence in mouse and human glioblastoma
Males exhibit higher incidence and worse prognosis for the majority of cancers, including glioblastoma (GBM). Disparate survival may be related to...
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The ontogenic gonadal transcriptomes provide insights into sex change in the ricefield eel Monopterus albus
BackgroundThe ricefield eel is a freshwater protogynous hermaphrodite fish and has become an important aquaculture species in China. The sex change...
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RNA sequencing and functional analysis of adult gonadal tissue to identify candidate key genes in Macrobrachium rosenbergii sex development
Macrobrachium rosenbergii is a typical aquatic organism with reversible gonadal development that is regulated by gene expression. The role of...
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dmrt3, nom1, abce1, and pkmyt1 play key roles in gonadal sex determination in Acrossocheilus fasciatus
Acrossocheilus fasciatus is an economically valuable freshwater fish species that inhabits streams. Female A. fasciatus grow faster and taste better...
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The influence of various doses of Moringa oleifera extract on the antioxidant trait, cytokines, reproductive hormones performance, and gonadal histological profiles of Nile tilapia
Moringa oleifera is a highly nutritious and water purifier plant that is widely utilized in the aquaculture sector. Tilapia fish has various...
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Gonadal lipidomics profile of an ovoviviparity teleost, black rockfish, during gonadal development
In order to study the variation of gonad lipidomics during reproductive cycle, black rockfish was employed as the research model in the present...
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Effect of prolonged photoperiod on growth, gonadal development, sex ratio, and skin coloration of red tilapia (O. mossambicus × O. urolepis hornorum)
Farming of red tilapia is one promising direction in aquaculture. The objective of this study was to investigate the impact of long-day photoperiod...