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Display of Oligo-α-1,6-Glycosidase from Exiguobacterium sibiricum on the Surface of Escherichia coli Cells
AbstractCell-surface display using anchor motifs of outer membrane proteins allows exposure of target peptides and proteins on the surface of...
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Crystal structure of metagenomic β-glycosidase MeBglD2 in complex with various saccharides
AbstractMetagenomic MeBglD2 is a glycoside hydrolase family 1 (GH1) β-glycosidase that has β-glucosidase, β-fucosidase, and β-galactosidase...
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Design and synthesis of phenoxymethybenzoimidazole incorporating different aryl thiazole-triazole acetamide derivatives as α-glycosidase inhibitors
A novel series of phenoxymethybenzoimidazole derivatives ( 9a-n ) were rationally designed, synthesized, and evaluated for their α-glycosidase...
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Novel glycosidase from Paenibacillus lactis 154 hydrolyzing the 28-O-β-d-glucopyranosyl ester bond of oleanane-type saponins
AbstractOleanane-type ginsenosides are a class of compounds with remarkable pharmacological activities. However, the lack of effective preparation...
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A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG
Changes in human IgG galactosylation and sialylation have been associated with several inflammatory diseases which are a major burden on the health...
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Upgrading the accumulation of ginsenoside Rd in Panax notoginseng by a novel glycosidase-producing endophytic fungus G11-7
A novel endophytic fungus producing beta-glucosidase was isolated and characterized from pigeon pea ( Cajanus cajan [L.] Millsp.), which has excellent...
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Incorporation of Pseudouridine into RNA for Biochemical and Biophysical Studies
Modification of RNA molecules has a significant effect on their structure and function. Many different examples of RNA modifications have been...
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Effect of Roundup on the Activities of Glycosidase in the Intestines of Typical and Facultative Ichthyophages as a Function of Temperature and pH
AbstractIn vitro studies of the effect of the herbicide Roundup (25 µg/L) on the activity of glycosidases that hydrolyze starch in the intestinal...
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Enzymes in Brewing and Wine Industries
Enzymes are the bio-catalysts used in breweries and wineries for the biochemical transformation of a substrate to produce finished products. Several...
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Biocatalytic strategies for the production of ginsenosides using glycosidase: current state and perspectives
AbstractPanax ginseng is a traditional Chinese medicine with significant pharmaceutical effects and broad application. Rare ginsenosides with high...
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Comparative evaluation of antioxidant, antiglycation and α-glucosidase inhibitory potential of some indigenous medicinal Trigonella species
The aim of the present study was to comprehensively and comparatively investigate the antioxidant, antiglycation and α-glucosidase inhibitory...
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Biosynthesis of 6-methyl-2,4-dihydroxyphenyl-β-D-glucopyranoside
Abstract6-methyl-2,4-dihydroxyphenyl-4-O-methyl-β-D-glucopyranoside is a strong radical scavenger and antioxidant with potential utilization value,...
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Discovery of enzymes to biotransform ginsenoside Rd into ginsenosides F2 and CK using metagenomics and genomic mining
Ginsenosides are the main active components of ginseng, including many types and different contents. Among them, minor ginsenosides have better...
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Unique properties of prothrombin in the bullhead shark Heterodontus japonicus: the first report of purification and characterization of a blood coagulation factor in Chondrichthyes
Prothrombin is a serine protease precursor of the blood coagulation system. In this study, the primary structure of prothrombin of a cartilaginous...
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Engineering novel S-glycosidase activity into extremo-adapted β-glucosidase by rational design
The breakdown of sulphur glycosidic bonds in thioglycosides can produce isothiocyanate, a chemoprotective agent linked to the prevention of cancers;...
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Priestia flexa KS1: A new bacterial strain isolated from human faeces implicated in mucin degradation
The human gut acts as a habitat for diverse microbial communities, including mucin utilizers that play a significant role in host health and...
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Pre-fertilization approach using α-l-fucosidase modulates zona pellucida hardening during bovine in vitro embryo production
The polyspermy occurrence is considerably lower under in vivo compared to in vitro embryo culture conditions, suggesting that the presence of some...
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Genome assembly of Medicago truncatula accession SA27063 provides insight into spring black stem and leaf spot disease resistance
Medicago truncatula , model legume and alfalfa relative, has served as an essential resource for advancing our understanding of legume physiology,...
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Genotoxicity of a novel thymol bearing oxipropanolamine derivative in human peripheral lymphocytes
[1-(2-isopropyl-5-methylphenoxy)-3-(yridine-3-ylmethylamino)propan-2-ol] is a novel oxipropanolamine derivative. It had been synthesized in a...
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Identification of a Coprinellus strain and its application in Eucommia ulmoides gum extraction by fermenting leaves
White rot fungi is a kind of filamentous fungi which can degrade lignin, hemicellulose and cellulose effectively. In this study, a wild white rot...
