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Conjugated linoleic acid and glucosamine supplements may prevent bone loss in aging by regulating the RANKL/RANK/OPG pathway
The skeleton is a living organ that undergoes constant changes, including bone formation and resorption. It is affected by various diseases, such as...
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An update on the review of microbial synthesis of glucosamine and N-acetylglucosamine
Glucosamine (GlcN) is a natural amino monosaccharide in which a hydroxyl group of glucose is substituted by an amino group. It belongs to functional...
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Efficient production of d-glucosamine by diacetylchitobiose deacetylase catalyzed deacetylation of N-acetyl-d-glucosamine
Objectived -Glucosamine (GlcN) is an important amino sugar with various applications in medicine, food & beverages, nutritional supplements, and...
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Synthesis and Characterization of Novel Biologically Active Pyrano[3,2-c]Chromene-Diones via Multicomponent Avenue on the Surface of Glucosamine Covalented NiFe2O4@Silicapropyl Nanoparticles
AbstractAn efficient, green and new avenue for the synthesis of novel derivatives of pyrano[3,2-c]chromene-diones using the reaction between...
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Anserine and glucosamine supplementation attenuates the levels of inflammatory markers in rats with rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disorder that affects the joint synovium. Anserine is a functional dipeptide containing methylhistidine...
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Map** and identification of CsSF4, a gene encoding a UDP-N-acetyl glucosamine-peptide N-acetylglucosaminyltransferase required for fruit elongation in cucumber (Cucumis sativus L.)
Key messageThe short fruit length phenotype in sf4 is caused by a SNP in Csa1G665390 , which encodes an O -linked N -acetylglucosamine (GlcNAc)...
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Improving enzyme activity of glucosamine-6-phosphate synthase by semi-rational design strategy and computer analysis
ObjectiveTo improve enzyme activity of Glucosamine-6-phosphate synthase (Glms) of Bacillus subtilis by site saturation mutagenesis at Leu 593 , Ala 594 ,...
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Structure and mechanism of lysosome transmembrane acetylation by HGSNAT
Lysosomal transmembrane acetylation of heparan sulfates (HS) is catalyzed by HS acetyl-CoA:α-glucosaminide N -acetyltransferase (HGSNAT), whose...
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Categories and biomanufacturing methods of glucosamine
Glucosamine (GlcN) is an amine sugar, in which a hydroxyl group of glucose is replaced with an amino group. It is an important part of the...
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Increasing outer membrane complexity: the case of the lipopolysaccharide lipid A from marine Cellulophaga pacifica
Gram-negative bacteria living in marine waters have evolved peculiar adaptation strategies to deal with the numerous stress conditions that...
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Metabolic phenotype analysis of Trichophyton rubrum after laser irradiation
BackgroundBiological phenotypes are important characteristics of microorganisms, and often reflect their genotype and genotype changes....
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Escherichia coli BL21(DE3) optimized deletion mutant as the host for whole-cell biotransformation of N‑acetyl‑d‑neuraminic acid
N ‑Acetyl‑ d ‑neuraminic acid (Neu5Ac) is the crucial compound for the chemical synthesis of antiflu medicine Zanamivir. Chemoenzymatic synthesis of...
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Deciphering the role of dissolved oxygen and N-acetyl glucosamine in governing higher molecular weight hyaluronic acid synthesis in Streptococcus zooepidemicus cell factory
The present study is focused on systematic process and kinetic investigation of hyaluronic acid (HA) production strategy unraveling the role of...
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Recombinant production, characterization and industrial application testing of a novel acidic exo/endo-chitinase from Rasamsonia emersonii
An acid-active exo/endo-chitinase; comprising a GH18 catalytic domain and substrate insertion domain; originating from the thermophilic filamentous...
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Nitrogen deposition enhances accumulation of microbial and plant-derived carbon in forest soils: a global meta-analysis
Background and AimsPlant and microbial-derived carbon (C) constitute the soil C pool and determine its response to N deposition. However, the...
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Glycolytic Inhibitors as Caloric Restriction Mimetics (CRM)
Aging is the loss of the physiological integrity of the living system over time, resulting in reduced function and a higher risk of death. In view of...
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Heparan Sulfate Structure: Methods to Study N-Sulfation and NDST Action
Heparan sulfate proteoglycans are important modulators of cellular processes where the negatively charged polysaccharide chains interact with target...
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Chemical Approaches to Prepare Modified Heparin and Heparosan Polymers for Biological Studies
Heparin is a potent clinically used anticoagulant. It is a heterogeneous mixture of polymers that contain a variety of sulfation patterns. Heparin...
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Effects of dissolved organic matter on soil aggregate dynamics using rare earth oxides as tracers in A Japanese Andisol
Background and aimsDissolved organic matter (DOM) stands out as a highly active component within the organic matter pool. It is hypothesized to play...
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Subtractive sequence analysis aided druggable targets mining in Burkholderia cepacia complex and finding inhibitors through bioinformatics approach
Burkholderia cepacia complex (BCC) is a group of gram-negative bacteria composed of at least 20 different species that cause diseases in plants,...
