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Production of ginsenoside compound K from American ginseng extract by fed-batch culture of Aspergillus tubingensis
Compound K (C-K), one of the most bioactive ginsenoside, is produced by hydrolyzing the glycoside moieties of protopanaxadiol (PPD)-type glycosylated...
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Production of ginsenoside compound K by microbial cell factory using synthetic biology-based strategy: a review
Ginsenoside compound K (CK) is a major intestinal bacterial metabolite of the protopanaxadiol-type ginsenoside family that can be absorbed in the...
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Novel glycosidase from Paenibacillus lactis 154 hydrolyzing the 28-O-β-d-glucopyranosyl ester bond of oleanane-type saponins
AbstractOleanane-type ginsenosides are a class of compounds with remarkable pharmacological activities. However, the lack of effective preparation...
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Cloning and characterization of thermophilic endoglucanase and its application in the transformation of ginsenosides
A novel endoglucanase (BcelFp) was identified from Fervidobaterium pennivorans DSM9078 which had biotransformation activity for protopanaxadiol...
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Cloning and Characterization of a Ginsenoside-Hydrolyzing α-L-Arabinofuranosidase, CaAraf51, From Cellulosimicrobium aquatile Lyp51
Moutai Jiuqu is a famous aromatic raw material of Maotai flavor liquor in China. It is brewed at high temperature and contains many kinds of...
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Advances in the biosynthesis and metabolic engineering of rare ginsenosides
AbstractRare ginsenosides are the deglycosylated secondary metabolic derivatives of major ginsenosides, and they are more readily absorbed into the...
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Enhancement of biotransformation of ginsenosides in white ginseng roots by aerobic co-cultivation of Bacillus subtilis and Trichoderma reesei
In the present work, the biotransformation of ginsenosides in white ginseng roots was innovatively investigated using the aerobic fermentation by the...
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Gut Microbiome for Ginseng Medicine
In the past few decades, using traditional Chinese medicines (TCMs), including Panax ginseng as pharmaceutical, nutraceutical, and healthcare...
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Synthetic Biology of Ginsenosides
Ginsenosides, a group of triterpenoid saponins, are the signature compounds from plants in the genus Panax. Ginsenosides display a variety of...
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Microbial α-L-arabinofuranosidases: diversity, properties, and biotechnological applications
Arabinoxylans (AXs) are hemicellulosic polysaccharides consisting of a linear backbone of β -1,4-linked xylose residues branched by high content of α -L...
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Efficient production of the anti-aging drug Cycloastragenol: insight from two Glycosidases by enzyme mining
AbstractThe telomerase activator cycloastragenol (CA) is regarded as a potential anti-aging drug with promising applications in the food and medical...
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High-density immobilization of a ginsenoside-transforming β-glucosidase for enhanced food-grade production of minor ginsenosides
Use of recombinant glycosidases is a promising approach for the production of minor ginsenosides, e.g., Compound K (CK) and F 1 , which have potential...
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Withanolides production by the endophytic fungus Penicillium oxalicum associated with Withania somnifera (L.) Dunal
Withanolides are steroidal lactones with diverse bioactive potential and their production from plant sources varies with genotype, age, culture...
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Extraction of Phytoconstituents for Lifestyle Diseases
Diseases whose occurrence is mainly related to an individual's daily living habits are referred to as lifestyle diseases. Some of these diseases...
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Bioactive components to inhibit foam cell formation in atherosclerosis
BackgroundThe production of lipid-laden cells in macrophages after significant ingestion of oxidized low-density lipoprotein is considered the most...
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A novel Lactiplantibacillus plantarum strain: probiotic properties and optimization of the growth conditions by response surface methodology
The objective of this study is to explore the probiotic properties and optimal growth conditions of Lactiplantibacillus plantarum BG24. L. plantarum ...
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Characterization and in-depth genome analysis of a halotolerant probiotic bacterium Paenibacillus sp. S-12, a multifarious bacterium isolated from Rauvolfia serpentina
BackgroundMembers of Paenibacillus genus from diverse habitats have attracted great attention due to their multifarious properties. Considering that...
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Enzymatic transformation of ginsenosides Re, Rg1, and Rf to ginsenosides Rg2 and aglycon PPT by using β-glucosidase from Thermotoga neapolitana
ObjectivesTo enzymatically transform protopanaxatriol by using β -glucosidase from Thermotoga neapolitana ( T. neapolitana ) DSM 4359.
Results ...
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Invisible Inhabitants of Plants and a Sustainable Planet: Diversity of Bacterial Endophytes and their Potential in Sustainable Agriculture
Uncontrolled usage of chemical fertilizers, climate change due to global warming, and the ever-increasing demand for food have necessitated...
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Chironomus riparius Larval Gut Bacteriobiota and Its Potential in Microplastic Degradation
Chironomus riparius are sediment-dwelling invertebrates in freshwater ecosystems and are used as indicators of environmental pollution. Their habitat...
