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Genomic Imprinting and Random Monoallelic Expression
AbstractThe review discusses the mechanisms of monoallelic expression, such as genomic imprinting, in which gene transcription depends on the...
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Tools and Techniques for Genomic Imprinting
Genomic imprinting is an epigenetic process in which the parents’ genes impact gene expression. Over the years, researchers have strived to identify...
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Genomic Imprinting
A typical cell contains two sets of chromosomes: one that was inherited from the mother, the other from the father. Usually, autosomal alleles are...
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Genomic Imprinting: A Paradigm for Epigenetics of Human Diseases
Genomic imprinting is a remarkable phenomenon through which certain genes show monoallelic expression depending on their parent of origin. While...
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Transcriptome-wide identification and characterization of genes exhibit allele-specific imprinting in maize embryo and endosperm
BackgroundGenomic imprinting refers to a subset of genes that are expressed from only one parental allele during seed development in plants. Studies...
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Conservation and divergence of canonical and non-canonical imprinting in murids
BackgroundGenomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and...
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Evolutionary Aspects of Genomic Imprinting
Abstract—Genomic imprinting is an epigenetic phenomenon that differentiates maternal and paternal copies of genes in the genome and causes...
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Imprinting at the KBTBD6 locus involves species-specific maternal methylation and monoallelic expression in livestock animals
BackgroundThe primary differentially methylated regions (DMRs) which are maternally hypermethylated serve as imprinting control regions (ICRs) that...
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Genomic dissection of additive and non-additive genetic effects and genomic prediction in an open-pollinated family test of Japanese larch
Genomic dissection of genetic effects on desirable traits and the subsequent use of genomic selection hold great promise for accelerating the rate of...
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Immune imprinting and next-generation coronavirus vaccines
Vaccines based on historical virus isolates provide limited protection from continuously evolving RNA viruses, such as influenza viruses or...
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Cloning, tissue expression and imprinting status analysis of the NDN gene in Dolang sheep
BackgroundGenomic imprinting refers to expressing parent-specific genes in mammalian diploid cells. The NDN gene is maternally imprinted in humans...
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EpiTy**: analysis of epigenetic aberrations in parental imprinting and X-chromosome inactivation using RNA-seq
Human pluripotent stem cells (hPSCs) hold a central role in studying human development, in disease modeling and in regenerative medicine. These cells...
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Epigenetic Regulation Disturbances on Gene Expression in Imprinting Diseases
Abstract—Epigenetic regulation is hereditary and non-hereditary changes in the expression of a particular gene without any corresponding structural...
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Flax Genomic Resources and Databases
Flax is an important crop producing high-quality fiber from its stem and seeds that are rich in omega-3 alpha-linolenic acid (ALA). During the past...
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Along the Bos taurus genome, uncover candidate imprinting control regions
BackgroundIn mammals, Imprinting Control Regions (ICRs) regulate a subset of genes in a parent-of-origin-specific manner. In both human and mouse,...
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The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex
BackgroundImprinting Control Regions (ICRs) are CpG-rich sequences acquiring differential methylation in the female and male germline and maintaining...
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The evolution of imprinting in plants: beyond the seed
Genomic imprinting results in the biased expression of alleles depending on if the allele was inherited from the mother or the father. Despite the...
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Placental imprinting of SLC22A3 in the IGF2R imprinted domain is conserved in therian mammals
BackgroundThe eutherian IGF2R imprinted domain is regulated by an antisense long non-coding RNA, Airn , which is expressed from a differentially...
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FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma
Lung cancer remains one of the most common malignancies and the leading cause of cancer-related death worldwide. Forkhead box protein A1 (FOXA1) is a...
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Nature of Genomic Architecture: A Topological Model of Genome
Our present understanding of genomic architecture is based on incremental addition of the manner in which genes are expressed. At present, there is...