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Multiple Traits and Genetic Correlation
This chapter introduces the concept of genetic correlation between traits. Causes of genetic correlation between traits are described: (1) pleiotropy...
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Genetic correlation for alcohol consumption between Europeans and East Asians
Genome-wide association studies (GWAS) have identified many genetic variants associated with alcohol consumption in Europeans and East Asians, as...
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Genetic correlation between smoking behavior and gastroesophageal reflux disease: insights from integrative multi-omics data
BackgroundObservational studies have preliminarily revealed an association between smoking and gastroesophageal reflux disease (GERD). However,...
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Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease
Chronic kidney diseases (CKD) have genetic associations with kidney function. Univariate genome-wide association studies (GWAS) have identified...
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Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study
BackgroundLongevity is one of the most complex phenotypes, and its genetic basis remains unclear. This study aimed to explore the genetic correlation...
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Genetic divergence and correlation estimates for quantitative traits in Salix
The study was conducted to estimate the genetic variability and stability in the performance of different Salix clones for important...
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Prediction of heterotic combinations using correlation between genetic distance, heterosis and combining ability in yellow sarson (Brassica rapa var. yellow sarson Prain)
Prediction of heterotic combinations from parental dissimilarity will improve the efficiency of heterosis breeding. This study was conducted to...
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Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits
Although the genetic correlations between complex traits have been estimated for more than a century, only recently we have started to map and...
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Assessing the between-country genetic correlation in maize yield using German and Polish official variety trials
Key messageWe assess the genetic gain and genetic correlation in maize yield using German and Polish official variety trials. The random coefficient...
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Genetic Attributes and Correlation Studies for Important Traits in Wheat Under Irrigated and Rainfed Conditions
Development of new and high yielding cultivars is the main goal of plant breeders. This research was conducted to determine genetic diversity,...
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Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study
BackgroundThe incidence of pulmonary embolism complications in the literature ranges from 10 to 50%, with a 0.5–10% risk of fatal pulmonary embolism....
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Genetic variation, correlation, and association map** of seed yield and its component traits in sesame
Sesame is an important and specific oilseed crop with high quality. Here, we systematically investigated the relationships between plant seed yield...
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Genetic diversity in Stryphnodendron adstringens (Mart.) Coville (Leguminosae, Caesalpinioideae, Clade Mimosoid) and its correlation with species richness of Stryphnodendron Mart. and related genera
Biodiversity is organized in three fundamental hierarchical levels in nature: diversity of genes within species, diversity of species in communities,...
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A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
Frailty is an aging-related clinical phenotype defined as a state in which there is an increase in a person’s vulnerability for dependency and/or...
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Evaluating the estimation of genetic correlation and heritability using summary statistics
While novel statistical methods quantifying the shared heritability of traits and diseases between ancestral distinct populations have been recently...
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SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
Local genetic correlation quantifies the genetic similarity of complex traits in specific genomic regions. However, accurate estimation of local...
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Analysis of genetic parameters of growth and wood traits provides insight into the genetic improvement of Schima superba
Schima superba (Theaceae) is widely distributed in subtropical China, and is the main timber and ecological afforestation tree species. This study...
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Raman Spectroscopy of Blood Serum for Essential Thrombocythemia Diagnosis: Correlation with Genetic Mutations and Optimization of Laser Wavelengths
Essential thrombocythemia (ET) is a type of myeloproliferative neoplasm that increases the risk of thrombosis. To diagnose this disease, the analysis...
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Genetic Studies on Behavior
Animal behavior is one of the most complex phenomena in biology. Understanding the cellular and molecular basis of behavior is one of the critical...
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Genetic and Genomic Resources of Bunium persicum (Boiss.) Fedtsch
Bunium persicum (Boiss.) Fedtsch, also known as black cumin, is an economically important medicinal spice plant growing in cold-temperate regions at...