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An overview and future prospects of recombinant protein production in Bacillus subtilis
Bacillus subtilis is a well-characterized Gram-positive bacterium and a valuable host for recombinant protein production because of its efficient...
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A cold shock protein promotes high-temperature microbial growth through binding to diverse RNA species
Endowing mesophilic microorganisms with high-temperature resistance is highly desirable for industrial microbial fermentation. Here, we report a...
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Prediction and validation of novel SigB regulon members in Bacillus subtilis and regulon structure comparison to Bacillales members
BackgroundSigma factor B (SigB) is the central regulator of the general stress response in Bacillus subtilis and regulates a group of genes in...
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SigB-regulated antioxidant functions in gram‐positive bacteria
Oxidative stress can have lethal consequences if organisms do not respond and remediate the damage to DNA, proteins and lipids. Bacterial species...
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ATP-Binding Cassette Transporters: Snap-on Complexes?
ATP-binding cassette (ABC) transporters are one of the largest families of membrane proteins in prokaryotic organisms. Much is now understood about...
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Associations of Internal-Migration Status with Maternal Exposure to Stress, Lead, and Selenium Deficiency Among Pregnant Women in Shanghai, China
Internal migration and urbanization are occurring on a global scale. Although the risk of exposure to stress/lead/low selenium is assumed to be high...
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Double promoter expression systems for recombinant protein production by industrial microorganisms
Using double promoter expression systems is a promising approach to increase heterologous protein production. In this review, current double promoter...
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Proteomic Analysis of Normal Expression Differences Exist in Bacillus Subtilis 168 Cultivation
Biological science discovery often involves comparing conditions to a normal state, but little is known about “normal.” Therefore, we used proteomic...
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Exploitation of Bacillus subtilis as a robust workhorse for production of heterologous proteins and beyond
Bacillus subtilis , belonging to the type species of Bacillus , is a type of soil-derived, low %G+C, endospore-forming Gram-positive bacterium. After...
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Ameliorating Salt Stress in Crops Through Plant Growth-Promoting Bacteria
Abiotic stresses are emerging vicious environmental factors limiting agricultural productivity around the world, while food demand is increasing with...
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Characterization and application of endogenous phase-dependent promoters in Bacillus subtilis
Bacillus subtilis as an important host has been widely used in synthetic biology, metabolic engineering, and production of industrial enzymes. To...
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The genome and genetics of a high oxidative stress tolerant Serratia sp. LCN16 isolated from the plant parasitic nematode Bursaphelenchus xylophilus
BackgroundPine wilt disease (PWD) is a worldwide threat to pine forests, and is caused by the pine wood nematode (PWN) Bursaphelenchus xylophilus ....
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Auto-inducible expression system based on the SigB-dependent ohrB promoter in Bacillus subtilis
A reliable production of heterologous proteins is important in the field of industrial biotechnology. This can be achieved by applying auto-inducible...
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Identification of Stringent Response-Related and Potential Serological Proteins Released from Bacillus anthracis Overexpressing the RelA/SpoT Homolog, Rsh Bant
RelA and SpoT synthesize ppGpp, a key effector molecule that facilitates the adaptation of bacteria to nutrient starvation and other stresses, known...
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Group 1 LEA proteins, an ancestral plant protein group, are also present in other eukaryotes, and in the archeae and bacteria domains
Water is an essential element for living organisms, such that various responses have evolved to withstand water deficit in all living species. The...
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Bacterial Stress Response
Bacteria respond to stress by regulatory networks which modulate gene expression. These response mechanisms are essential for co** with the stress...
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Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
BackgroundGene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to...
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Genetic approaches towards overcoming water deficit in plants - special emphasis on LEAs
Water deficit arises as a result of low temperature, salinity and dehydration, thereby affecting plant growth adversely and making it imperative for...
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Computational Prediction of Genomic Functional Cores Specific to Different Microbes
Computational and experimental attempts tried to characterize a universial core of genes representing the minimal set of functional needs for an...
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