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A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation
BackgroundThe coordinated transcriptional regulation of activated T-cells is based on a complex dynamic behavior of signaling networks. Given an...
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Identification of drug responsive enhancers by predicting chromatin accessibility change from perturbed gene expression profiles
Individual may response to drug treatment differently due to their genetic variants located in enhancers. These variants can alter transcription...
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A Hands-On Guide to Generate Spatial Gene Expression Profiles by Integrating scRNA-seq and 3D-Reconstructed Microscope-Based Plant Structures
Transcriptome profiles of individual cells in the plant are strongly dependent on their relative position. Cell differentiation is associated with...
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Disruption of Long-Distance Transport Leads to Changes in Gene Expression Profiles of Sugar Transporters in Silver Birch
AbstractKarelian birch is a form of silver birch that is characterized by a violation of the ratio and spatial orientation of the structural elements...
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Dataset including whole blood gene expression profiles and matched leukocyte counts with utility for benchmarking cellular deconvolution pipelines
ObjectivesCellular deconvolution is a valuable computational process that can infer the cellular composition of heterogeneous tissue samples from...
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Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease
Epstein–Barr virus (EBV) is an aetiologic risk factor for the development of multiple sclerosis (MS). However, the role of EBV-infected B cells in...
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Inferring gene expression from cell-free DNA fragmentation profiles
Profiling of circulating tumor DNA (ctDNA) in the bloodstream shows promise for noninvasive cancer detection. Chromatin fragmentation features have...
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High-dimensional gene expression and morphology profiles of cells across 28,000 genetic and chemical perturbations
Cells can be perturbed by various chemical and genetic treatments and the impact on gene expression and morphology can be measured via transcriptomic...
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Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission
It has been proposed that neuroinflammatory response plays an important role in the neurovascular remodeling in the brain after stress. The goal of...
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Omic horizon expression: a database of gene expression based on RNA sequencing data
BackgroundGene expression profiles have important significance for gene expression characteristics and further functional studies. More attention has...
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On triangle inequalities of correlation-based distances for gene expression profiles
BackgroundDistance functions are fundamental for evaluating the differences between gene expression profiles. Such a function would output a low...
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Evolutionary changes in gene expression profiles associated with the coevolution of male and female genital parts among closely related ground beetle species
BackgroundThe coevolutionary dynamics of corresponding male and female sexual traits, including genitalia, may be driven by complex genetic...
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Comparative Transcriptomics Reveals Novel Spatial Gene Expression Profiles in Cotton (Gossypium hirsutum L.) Under Herbivory and Drought Stress
Cotton is the major natural fiber-producing crop, contributing significantly to the global textile economy. However, the cotton crop encounters...
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Genome-wide investigation of NLP gene family members in alfalfa (Medicago sativa L.): evolution and expression profiles during development and stress
BackgroundNIN-like protein (NLP) transcription factors (TFs) compose a plant-specific gene family whose members play vital roles in plant...
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Spaceflight induces changes in gene expression profiles linked to insulin and estrogen
Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans . Here,...
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PEATmoss: A Gene Expression Atlas for Bryophytes
PEATmoss is an interactive gene expression atlas for bryophytes, which originally unified Physcomitrium patens RNA-seq and microarray expression data...
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Integrative Analysis of Gene Expression and Alternative Polyadenylation from Single-Cell RNA-seq Data
Single-cell RNA-seq (scRNA-seq) is a powerful technique for assaying transcriptional profile of individual cells. However, high dropout rate and...
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Characterization and expression profiles of the B-box gene family during plant growth and under low-nitrogen stress in Saccharum
BackgroundB-box (BBX) zinc-finger transcription factors play crucial roles in plant growth, development, and abiotic stress responses. Nevertheless,...
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Gene Expression in Medicinal Plants in Stress Conditions
Medicinal plants have been in use for hundreds of years for the betterment of mankind against a plethora of ailments in different parts of the world....
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Scenarios for the Integration of Microarray Gene Expression Profiles in COVID-19–Related Studies
The COVID-19 pandemic has hit heavily many aspects of our lives. At this time, genomic research is concerned with exploiting available datasets and...