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Evolution of gallium applications in medicine and microbiology: a timeline
Characterized as a semi-metal, gallium is a chemical element not found freely in the environment, but extracted as a by-product from other minerals....
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Effect of gallium nitrate on the antibacterial activity of vancomycin in methicillin-sensitive and resistant Staphylococcus aureus
The extension of multidrug-resistant strains of Staphylococcus aureus ( S. aureus ) is one of the main health challenges in the world, which requires...
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Quantitative proteomic reveals gallium maltolate induces an iron-limited stress response and reduced quorum-sensing in Pseudomonas aeruginosa
Gallium-based drugs have been repurposed as antibacterial therapeutic candidates and have shown significant potential as an alternative treatment...
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Relevance of FeoAB system in Rhodanobacter sp. B2A1Ga4 resistance to heavy metals, aluminium, gallium, and indium
AbstractAluminium (Al), gallium (Ga), and indium (In) are metals widely used in diverse applications in industry, which consequently result in a...
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Characterization of gallium resistance induced in a Pseudomonas aeruginosa cystic fibrosis isolate
The repurposing of gallium nitrate as an antibacterial, a drug used previously for the treatment of hypercalcemia, is a plausible alternative to...
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Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68
AbstractIn recent years, clinical imaging with zirconium-89 ( 89 Zr)-labelled monoclonal antibodies (Ab) by positron emission tomography (immunoPET)...
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Novel contrast media based on the liquid metal gallium for in vivo digestive tract radiography: a feasibility study
The barium sulfate has been playing an important role as the contrast medium in gastrointestinal radiography and disease diagnosis. However, its...
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Assessing Metal Toxicity on Crustaceans in Aquatic Ecosystems: A Comprehensive Review
Residual concentrations of some trace elements and lightweight metals, including cadmium, copper, lead, mercury, silver, zinc, nickel, chromium,...
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Investigation of combined photodynamic and radiotherapy effects of gallium phthalocyanine chloride on MCF-7 breast cancer cells
In this study, we evaluated the effect of gallium phthalocyanine chloride (GaPcCl) as a radio- and photosensitizer on MCF-7 breast cancer cell line....
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Exploring the Role of Heavy Metals and Their Derivatives on the Pathophysiology of COVID-19
Many aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been studied to determine its...
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Photoelectrochemistry of metalloporphyrin-modified GaP semiconductors
Photoelectrosynthetic materials provide a bioinspired approach for using the power of the sun to produce fuels and other value-added chemical...
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Ga(III) pyridinecarboxylate complexes: potential analogues of the second generation of therapeutic Ga(III) complexes?
A series of novel Ga(III)—pyridine carboxylates ([Ga(Pic) 3 ]·H 2 O (GaPic; HPic = picolinic acid), H 3 O[Ga(Dpic) 2 ]·H 2 O (GaDpic; H 2 Dpic = dipicolinic...
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Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer
To explore highly selective targeting molecules of colorectal cancer (CRC) is a challenge. We previously identified a twelve-amino acid peptide...
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Distribution of Trophic Resources in a Rodent Community in the High-Mountain Zone of the Republic of Dagestan
AbstractQuantitative and qualitative characteristics of nutrition of some cohabiting rodent species in the High-Mountain Zone of the Republic of...
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Biofilm-specific uptake of a 4-pyridone-based iron chelator by Pseudomonas aeruginosa
Iron is an essential nutrient for virtually all microbes and limiting the concentration of available iron is a potential strategy to be used as an...
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Contrasting Role of Fungal Siderophore in Metal Ion Complex Formation
Siderophores are tiny organic molecules secreted by microbes in iron-restricted environment to make iron available for its functioning and growth.... -
Cryo-Focused Ion Beam Milling of Cells
Cryo-electron tomography (cryo-ET) is a robust technique for bringing structural biology into the cellular context. However, transmission electron... -
A new 68Ga-labeled ornithine derivative for PET imaging of ornithine metabolism in tumors
Ornithine metabolism plays a vital role in tumorigenesis. For cancer cells, ornithine is mainly used as a substrate for ornithine decarboxylase (ODC)...
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Search for new antimicrobials: spectroscopic, spectrometric, and in vitro antimicrobial activity investigation of Ga(III) and Fe(III) complexes with aroylhydrazones
The in vitro antimicrobial activity of Fe(III) and Ga(III) complexes with N '-(2,3-dihydroxy-phenylmethylidene)-3-pyridinecarbohydrazide ( H 2 L 1 ), N '-(2,...
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Algorithm for Modern Electron Microscopic Examination of the Golgi Complex
The Golgi complex (GC) is an essential organelle of the eukaryotic exocytic pathway. It has a very complexed structure and thus localization of its...