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In Silico functional and phylogenetic analyses of fungal immunomodulatory proteins of some edible mushrooms
Mushrooms are a well known source of many bioactive and nutritional compounds with immense applicability in both the pharmaceutical and food...
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The potential role of plant secondary metabolites on antifungal and immunomodulatory effect
AbstractWith the widespread use of antibiotic drugs worldwide and the global increase in the number of immunodeficient patients, fungal infections...
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Ganoderma immunomodulatory proteins: mushrooming functional FIPs
AbstractFungal immunomodulatory protein (FIP) is a novel functional protein family with specific immunomodulatory activity identified from several...
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Immunomodulatory Potential of Hedwigia ciliata and Hypnum cupressiforme
Hedwigia ciliata (Hedw.) P. Beauv. and Hypnum cupressiforme Hedw. are two widespread moss representatives, which belong to the second largest group...
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Mining chicken ileal microbiota for immunomodulatory microorganisms
The gut microbiota makes important contributions to host immune system development and resistance to pathogen infections, especially during early...
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Fungal vaccines and adjuvants: a tool to reveal the interaction between host and fungi
Fungal infections are incurring high risks in a range from superficial mucosal discomforts (such as oropharyngeal candidiasis and vulvovaginal...
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Fungal Enzyme-Based Nutraceutical Oligosaccharides
Prebiotic oligosaccharides are receiving immense attention due to their nutraceutical and therapeutic potential associated with the food and...
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Immunomodulatory Potential of Hedwigia ciliata and Hypnum cupressiforme
Hedwigia ciliata (Hedw.) P. Beauv. and Hypnum cupressiforme Hedw. are two widespread moss representatives, which belong to the second largest group...
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Microbiota-derived short chain fatty acids in fermented Kidachi Aloe promote antimicrobial, anticancer, and immunomodulatory activities
BackgroundFermented Aloe leaf juice is a commonly used food supplement in Japan. In a previous study, fermentation of A. arborescence juice was...
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The pathobiology of human fungal infections
Human fungal infections are a historically neglected area of disease research, yet they cause more than 1.5 million deaths every year. Our...
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Bioinformatics Approaches in Studying the Fungal Endophyte-Derived Bioactive Compounds with Pharmacological Relevance
Fungal endophytes (FEs) are endosymbionts that live inside the plant and produce compounds that protect the host from predators like grazing animals,...
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Metabolic profiling, antimicrobial, anticancer, and in vitro and in silico immunomodulatory investigation of Aspergillus niger OR730979 isolated from the Western Desert, Egypt
Ten fungal species were isolated from soil in the Western Desert and Wadi El-Natron in Egypt. All fungal isolates were morphologically recognized...
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Functional evaluation of a recombinant fungal immunomodulatory protein from L. rhinocerus produced in P. pastoris and E. coli host expression systems
AbstractFungal immunomodulatory proteins (FIPs) are bioactive proteins with immunomodulatory properties. We previously reported the heterologous...
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Exploring fungal bioemulsifiers: insights into chemical composition, microbial sources, and cross-field applications
The demand for emulsion-based products is crucial for economic development and societal well-being, spanning diverse industries such as food,...
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Microbial allies: exploring fungal endophytes for biosynthesis of terpenoid indole alkaloids
Terpenoid indole alkaloids (TIAs) are natural compounds found in medicinal plants that exhibit various therapeutic activities, such as antimicrobial,...
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COVID-19-associated fungal infections
Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill,...
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Fungal Polysaccharides as Biosurfactants and Bioemulsifiers
Fungi play a substantial role in tackling major challenges in the world. Applications of fungal processes and materials is directly related to the...
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The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production
Host defense peptides (HDPs) are small molecules with broad-spectrum antimicrobial activities against infectious bacteria, viruses, and fungi....
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Therapeutic and immunomodulatory role of probiotics in breast cancer: A mechanistic review
Breast cancer has become the most prevalent and noxious type of malignancy around the globe (Giaquinto et al., 2022). Multiple clinical strategies...
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Recent drug development and treatments for fungal infections
Fungal infections are now becoming a hazard to individuals which has paved the way for research to expand the therapeutic options available. Recent...
